JP5976986B2 - 調節可能な融合プロモーター - Google Patents

調節可能な融合プロモーター Download PDF

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Publication number
JP5976986B2
JP5976986B2 JP2008533689A JP2008533689A JP5976986B2 JP 5976986 B2 JP5976986 B2 JP 5976986B2 JP 2008533689 A JP2008533689 A JP 2008533689A JP 2008533689 A JP2008533689 A JP 2008533689A JP 5976986 B2 JP5976986 B2 JP 5976986B2
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promoter
cell
pol
construct
dependent
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Expired - Fee Related
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JP2008533689A
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Japanese (ja)
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JP2009509544A (ja
JP2009509544A5 (enExample
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チャールズ スタウト，
チャールズ スタウト，
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2008533689A 2005-10-01 2006-09-29 調節可能な融合プロモーター Expired - Fee Related JP5976986B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72256805P 2005-10-01 2005-10-01
US60/722,568 2005-10-01
PCT/US2006/038154 WO2007041350A2 (en) 2005-10-01 2006-09-29 Regulatable fusion promoters

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2012219504A Division JP2012254098A (ja) 2005-10-01 2012-10-01 調節可能な融合プロモーター
JP2015175115A Division JP6199934B2 (ja) 2005-10-01 2015-09-04 調節可能な融合プロモーター

Publications (3)

Publication Number Publication Date
JP2009509544A JP2009509544A (ja) 2009-03-12
JP2009509544A5 JP2009509544A5 (enExample) 2010-11-18
JP5976986B2 true JP5976986B2 (ja) 2016-08-24

Family

ID=37906746

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2008533689A Expired - Fee Related JP5976986B2 (ja) 2005-10-01 2006-09-29 調節可能な融合プロモーター
JP2012219504A Pending JP2012254098A (ja) 2005-10-01 2012-10-01 調節可能な融合プロモーター
JP2015175115A Expired - Fee Related JP6199934B2 (ja) 2005-10-01 2015-09-04 調節可能な融合プロモーター

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2012219504A Pending JP2012254098A (ja) 2005-10-01 2012-10-01 調節可能な融合プロモーター
JP2015175115A Expired - Fee Related JP6199934B2 (ja) 2005-10-01 2015-09-04 調節可能な融合プロモーター

Country Status (6)

Country Link
US (1) US20090053295A1 (enExample)
EP (2) EP2386564B1 (enExample)
JP (3) JP5976986B2 (enExample)
AU (1) AU2006297112B2 (enExample)
CA (1) CA2665080C (enExample)
WO (1) WO2007041350A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008543281A (ja) * 2005-06-09 2008-12-04 エイジェンシー フォー サイエンス， テクノロジー アンド リサーチ 肝臓星状細胞特異的プロモーターおよびその使用
US20070299029A1 (en) * 2005-06-09 2007-12-27 Agency For Science, Technology And Research Hepatic stellate cell specific promoter and uses thereof
US20100331389A1 (en) * 2008-09-22 2010-12-30 Bob Dale Brown Compositions and methods for the specific inhibition of gene expression by dsRNA containing modified nucleotides
US8829173B2 (en) 2008-09-26 2014-09-09 Tocagen Inc. Recombinant vectors
EP3502256A3 (en) * 2008-09-26 2019-09-25 Tocagen Inc. Recombinant vectors
US8513207B2 (en) * 2008-12-18 2013-08-20 Dicerna Pharmaceuticals, Inc. Extended dicer substrate agents and methods for the specific inhibition of gene expression
EP2909324B1 (en) 2012-10-25 2020-02-26 Tocagen Inc. Retroviral vector with mini-promoter cassette
AU2016317936A1 (en) 2015-09-04 2018-03-08 Tocagen Inc. Recombinant vectors comprising 2A peptide
EP3796934A4 (en) * 2018-05-23 2022-04-06 Manysmart Therapeutics, Inc. BISPECIFIC T-LYMPHOCYTE ACTIVATOR AND USES THEREOF

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US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US5573933A (en) 1987-04-14 1996-11-12 Luminis Pty, Ltd. Transgenic pigs
US5166320A (en) 1987-04-22 1992-11-24 University Of Connecticut Carrier system and method for the introduction of genes into mammalian cells
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
ATE190354T1 (de) * 1990-12-20 2000-03-15 Arch Dev Corp The University O Kontrolle der genexpression durch ionisierende strahlung
US5922854A (en) 1991-06-14 1999-07-13 Kumar; Ramesh Purifying Human Hemogloblin from transgenic pig red cells and plasmids containing pig globin nucleic acids
WO1993025071A1 (en) 1992-06-12 1993-12-23 Dnx Corporation Production of human hemoglobin in transgenic pigs
US5523226A (en) * 1993-05-14 1996-06-04 Biotechnology Research And Development Corp. Transgenic swine compositions and methods
FR2738842B1 (fr) * 1995-09-15 1997-10-31 Rhone Poulenc Rorer Sa Molecule d'adn circulaire a origine de replication conditionnelle, leur procede de preparation et leur utilisation en therapie genique
US5874304A (en) * 1996-01-18 1999-02-23 University Of Florida Research Foundation, Inc. Humanized green fluorescent protein genes and methods
US6818209B1 (en) 1998-05-22 2004-11-16 Oxford Biomedica (Uk) Limited Retroviral delivery system
US6924123B2 (en) * 1996-10-29 2005-08-02 Oxford Biomedica (Uk) Limited Lentiviral LTR-deleted vector
DE19751587A1 (de) * 1997-11-21 1999-07-29 Hoechst Marion Roussel De Gmbh Onkogen- oder virusgesteuerte Expressionssysteme
DE19756975A1 (de) * 1997-12-20 1999-06-24 Hoechst Marion Roussel De Gmbh Bindungspartner für Inhibitoren von cyclinabhängigen Kinasen und ihre Verwendung zur Suche nach Inhibitoren, zur Diagnose oder zur Therapie einer Erkrankung
WO1999065515A2 (en) * 1998-06-15 1999-12-23 Arch Development Corporation Combination of radiotherapy and anti-angiogenic factors
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WO2000055335A1 (en) 1999-03-16 2000-09-21 Dana-Farber Cancer Institute, Inc. Pseudotyped lentiviral vectors and uses thereof
WO2000072886A1 (en) * 1999-05-26 2000-12-07 Dana-Farber Cancer Institute, Inc. Episomally replicating lentiviral vectors
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Also Published As

Publication number Publication date
HK1121165A1 (en) 2009-04-17
EP2386564A1 (en) 2011-11-16
AU2006297112A1 (en) 2007-04-12
JP6199934B2 (ja) 2017-09-20
JP2009509544A (ja) 2009-03-12
JP2016000047A (ja) 2016-01-07
EP2386564B1 (en) 2014-07-16
EP1943265A4 (en) 2009-01-14
CA2665080A1 (en) 2007-04-12
US20090053295A1 (en) 2009-02-26
CA2665080C (en) 2015-11-24
WO2007041350A2 (en) 2007-04-12
JP2012254098A (ja) 2012-12-27
EP1943265A2 (en) 2008-07-16
EP1943265B1 (en) 2012-09-12
AU2006297112B2 (en) 2013-04-18
WO2007041350A3 (en) 2007-10-04

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