JP5973066B2 - プレフィルドシリンジの製造方法及びプレフィルドシリンジ製造装置 - Google Patents

プレフィルドシリンジの製造方法及びプレフィルドシリンジ製造装置 Download PDF

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Publication number
JP5973066B2
JP5973066B2 JP2015515761A JP2015515761A JP5973066B2 JP 5973066 B2 JP5973066 B2 JP 5973066B2 JP 2015515761 A JP2015515761 A JP 2015515761A JP 2015515761 A JP2015515761 A JP 2015515761A JP 5973066 B2 JP5973066 B2 JP 5973066B2
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JP
Japan
Prior art keywords
gasket
outer cylinder
prefilled syringe
peripheral surface
cylinder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP2015515761A
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English (en)
Japanese (ja)
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JPWO2014181474A1 (ja
Inventor
等 沖原
等 沖原
亜莉紗 山下
亜莉紗 山下
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Terumo Corp
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Terumo Corp
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Expired - Fee Related legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B7/00—Closing containers or receptacles after filling
    • B65B7/16—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons
    • B65B7/161—Sealing filled ampoules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/1782—Devices aiding filling of syringes in situ
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B31/00—Packaging articles or materials under special atmospheric or gaseous conditions; Adding propellants to aerosol containers
    • B65B31/02—Filling, closing, or filling and closing, containers or wrappers in chambers maintained under vacuum or superatmospheric pressure or containing a special atmosphere, e.g. of inert gas
    • B65B31/025—Filling, closing, or filling and closing, containers or wrappers in chambers maintained under vacuum or superatmospheric pressure or containing a special atmosphere, e.g. of inert gas specially adapted for rigid or semi-rigid containers
    • B65B31/027—Filling, closing, or filling and closing, containers or wrappers in chambers maintained under vacuum or superatmospheric pressure or containing a special atmosphere, e.g. of inert gas specially adapted for rigid or semi-rigid containers closed by a stopper
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B7/00—Closing containers or receptacles after filling
    • B65B7/16—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons
    • B65B7/28—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons by applying separate preformed closures, e.g. lids, covers
    • B65B7/2821—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons by applying separate preformed closures, e.g. lids, covers applying plugs or threadless stoppers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2207/00—Methods of manufacture, assembly or production
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2207/00—Methods of manufacture, assembly or production
    • A61M2207/10—Device therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2209/00—Ancillary equipment
    • A61M2209/04—Tools for specific apparatus
    • A61M2209/045—Tools for specific apparatus for filling, e.g. for filling reservoirs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/003—Filling medical containers such as ampoules, vials, syringes or the like

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
JP2015515761A 2013-05-10 2013-05-10 プレフィルドシリンジの製造方法及びプレフィルドシリンジ製造装置 Expired - Fee Related JP5973066B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2013/063210 WO2014181474A1 (ja) 2013-05-10 2013-05-10 プレフィルドシリンジの製造方法及びプレフィルドシリンジ製造装置

Publications (2)

Publication Number Publication Date
JP5973066B2 true JP5973066B2 (ja) 2016-08-23
JPWO2014181474A1 JPWO2014181474A1 (ja) 2017-02-23

Family

ID=51866973

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015515761A Expired - Fee Related JP5973066B2 (ja) 2013-05-10 2013-05-10 プレフィルドシリンジの製造方法及びプレフィルドシリンジ製造装置

Country Status (6)

Country Link
US (1) US20150190578A1 (enExample)
EP (1) EP2995333A4 (enExample)
JP (1) JP5973066B2 (enExample)
CN (1) CN104602738B (enExample)
IN (1) IN2015DN02537A (enExample)
WO (1) WO2014181474A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230005155A (ko) * 2020-03-16 2023-01-09 더블유.엘. 고어 앤드 어소시에이트스, 인코포레이티드 무급유 시린지 스토퍼의 삽입을 위한 진공 삽입 방법 및 이를 위한 조립 시스템

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TW201900138A (zh) * 2013-08-16 2019-01-01 加拿大商凡爾克斯醫藥系統公司 用於裝填藥物容器的方法
US12515832B2 (en) 2013-08-16 2026-01-06 Vanrx Pharmasystems Inc. Method, device and system for filling pharmaceutical containers
US10266293B1 (en) * 2014-09-15 2019-04-23 Automated Systems of Tacoma LLC Method and system for vacuum stoppering of fluid containers
WO2017044112A1 (en) * 2015-09-11 2017-03-16 West Pharmaceutical Services, Inc. Medical administration barrel with grooves and method of sealing same
CN109641099B (zh) * 2016-08-23 2021-12-03 泰尔茂株式会社 注射器包装体
US10781001B2 (en) * 2016-12-01 2020-09-22 Fenwal, Inc. Fill and finish systems and methods
AU2017420758A1 (en) * 2017-06-29 2020-01-02 Regeneron Pharmaceuticals Inc. Devices and methods for overfilling drug containers
WO2019011961A1 (en) * 2017-07-11 2019-01-17 Becton Dickinson France DEVICE FOR VACUUM BLOCKING OF A MEDICAL CONTAINER
CN110914161B (zh) * 2017-07-11 2021-09-28 贝克顿迪金森法国公司 用于对医用容器进行真空和通气管加塞的设备
DE102017128957A1 (de) * 2017-12-06 2019-06-06 3lmed GmbH Kolben und System zum luftfreien Einsetzen des Kolbens mit einem Setzwerkzeug in einen Behälter
CN113164687B (zh) * 2018-11-27 2023-02-17 W.L.戈尔及同仁股份有限公司 将无润滑剂止挡件插入无润滑剂针筒的方法及组装系统
CN113811488B (zh) * 2019-05-23 2024-05-03 吉第联合股份公司 用制药工业的液体产品填充容器的填充单元
IT201900007551A1 (it) * 2019-05-30 2020-11-30 Gd Spa Unità di riempimento di un contenitore per prodotti liquidi, in particolare una carpula del settore farmaceutico
DE102019214071A1 (de) * 2019-09-16 2021-03-18 Rentschler Biopharma SE Vorrichtung und Verfahren zum Verschließen von Spritzenkörpern
CN115666687A (zh) * 2020-05-22 2023-01-31 W.L.戈尔及同仁股份有限公司 将无润滑剂止挡件插入无润滑剂针筒或无润滑剂药筒管的方法及用于组装其的系统
CN111806776B (zh) * 2020-07-15 2022-04-05 长沙一星制药机械有限公司 预充式注射器灌封机
WO2022049006A1 (en) * 2020-09-02 2022-03-10 Janssen Pharmaceutica Nv Pre-filled syringe with optimized stopper placement
DE102020131098A1 (de) * 2020-11-24 2022-05-25 Syntegon Technology Gmbh Vorrichtung zum Verschließen von pharmazeutischen Behältnissen
DE102021104302A1 (de) * 2021-02-23 2022-08-25 Syntegon Technology Gmbh Vorrichtung und Verfahren zum kraftgesteuerten Verschließen von pharmazeutischen Behältnissen
EP4144653A1 (en) * 2021-09-02 2023-03-08 Steriline S.r.l. Control method of an electromechanical apparatus for installing a bung element of a pharmaceutical container
US20250009976A1 (en) * 2021-12-03 2025-01-09 Amgen Inc. Stopper placement in a syringe
JP2025507945A (ja) * 2022-03-04 2025-03-21 エスアイオーツー・メディカル・プロダクツ・インコーポレイテッド 低摩擦オイルフリーシリンジプランジャー供給管およびプランジャーをシリンジ内に供給するためにそれを使用する方法
CN119451894A (zh) * 2022-06-26 2025-02-14 凡尔克斯医药系统公司 用于将药物真空密封到容器中的设备和方法
WO2024242865A1 (en) * 2023-05-24 2024-11-28 Becton, Dickinson And Company Stoppering tool system for installing a valved stopper in a syringe barrel

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0428386B2 (enExample) * 1989-04-21 1992-05-14 Akyuretsukusu Kk
JPH09299480A (ja) * 1996-05-16 1997-11-25 Eisai Co Ltd 打栓方法と装置、既充填シリンジおよびその製造方法と装置
JP2008212213A (ja) * 2007-02-28 2008-09-18 Hisamitsu Pharmaceut Co Inc 真空打栓用治具

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JP2583720B2 (ja) * 1992-09-09 1997-02-19 渋谷工業株式会社 真空打栓機
JP3282322B2 (ja) * 1993-10-29 2002-05-13 澁谷工業株式会社 密封容器とその製造方法
DE19647694C1 (de) * 1996-11-05 1998-06-04 Schering Ag Verfahren zur Herstellung einer vorgefüllten, sterilen Spritze
JP3387775B2 (ja) * 1997-05-22 2003-03-17 株式会社大協精工 注射器用密封栓及びプレフィルド注射器
DE19909995A1 (de) * 1999-03-06 2000-09-07 Inova Pac Systeme Gmbh Verfahren und Vorrichtung zum Befüllen und/oder Evakuieren von Behältern
JP2002089717A (ja) * 2000-09-14 2002-03-27 Terumo Corp ガスケット
US20060168916A1 (en) * 2004-11-05 2006-08-03 Griebel Robert A E Method and apparatus to insert stoppers into prefilled syringes
WO2010064667A1 (ja) * 2008-12-03 2010-06-10 電気化学工業株式会社 シリンジ

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0428386B2 (enExample) * 1989-04-21 1992-05-14 Akyuretsukusu Kk
JPH09299480A (ja) * 1996-05-16 1997-11-25 Eisai Co Ltd 打栓方法と装置、既充填シリンジおよびその製造方法と装置
JP2008212213A (ja) * 2007-02-28 2008-09-18 Hisamitsu Pharmaceut Co Inc 真空打栓用治具

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230005155A (ko) * 2020-03-16 2023-01-09 더블유.엘. 고어 앤드 어소시에이트스, 인코포레이티드 무급유 시린지 스토퍼의 삽입을 위한 진공 삽입 방법 및 이를 위한 조립 시스템
KR102817044B1 (ko) * 2020-03-16 2025-06-04 더블유. 엘. 고어 앤드 어소시에이트스, 인코포레이티드 무급유 시린지 스토퍼의 삽입을 위한 진공 삽입 방법 및 이를 위한 조립 시스템

Also Published As

Publication number Publication date
WO2014181474A1 (ja) 2014-11-13
US20150190578A1 (en) 2015-07-09
EP2995333A1 (en) 2016-03-16
JPWO2014181474A1 (ja) 2017-02-23
EP2995333A4 (en) 2017-01-04
CN104602738B (zh) 2017-03-08
CN104602738A (zh) 2015-05-06
IN2015DN02537A (enExample) 2015-09-11

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