JP5967861B2 - 分子のグリコシル化 - Google Patents

分子のグリコシル化 Download PDF

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JP5967861B2
JP5967861B2 JP2010501617A JP2010501617A JP5967861B2 JP 5967861 B2 JP5967861 B2 JP 5967861B2 JP 2010501617 A JP2010501617 A JP 2010501617A JP 2010501617 A JP2010501617 A JP 2010501617A JP 5967861 B2 JP5967861 B2 JP 5967861B2
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protein
modified
glycosylation
cells
activity
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JP2010523102A5 (enExample
JP2010523102A (ja
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ニコ ルーク マルク カレヴェルト，
ニコ ルーク マルク カレヴェルト，
ウーテル ベルベッケン，
ウーテル ベルベッケン，
デ プールク， カレン ジャクリーン マルセル
デ プールク， カレン ジャクリーン マルセル
スティーブン クリスチャン ヨゼフ ヘイセンス，
スティーブン クリスチャン ヨゼフ ヘイセンス，
マウナ ハエルファル，
マウナ ハエルファル，
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オキシレイン ユーケー リミテッド
オキシレイン ユーケー リミテッド
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2477—Hemicellulases not provided in a preceding group
    • C12N9/2488—Mannanases
    • A—HUMAN NECESSITIES
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    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
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    • C12N15/09—Recombinant DNA-technology
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    • C12N9/10—Transferases (2.)
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    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
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    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2465—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on alpha-galactose-glycoside bonds, e.g. alpha-galactosidase (3.2.1.22)
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    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
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    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/01—Hexosyltransferases (2.4.1)
    • C12Y204/01232—Initiation-specific alpha-1,6-mannosyltransferase (2.4.1.232)
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    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01024—Alpha-mannosidase (3.2.1.24)
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    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01045—Glucosylceramidase (3.2.1.45), i.e. beta-glucocerebrosidase
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    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01046—Galactosylceramidase (3.2.1.46)
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    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01084—Glucan 1,3-alpha-glucosidase (3.2.1.84), i.e. mutanase
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    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01113—Mannosyl-oligosaccharide 1,2-alpha-mannosidase (3.2.1.113), i.e. alpha-1,2-mannosidase
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JP2010501617A 2007-04-03 2008-04-03 分子のグリコシル化 Expired - Fee Related JP5967861B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US90990407P 2007-04-03 2007-04-03
US60/909,904 2007-04-03
US94021207P 2007-05-25 2007-05-25
US60/940,212 2007-05-25
PCT/IB2008/001814 WO2008120107A2 (en) 2007-04-03 2008-04-03 Glycosylation of molecules

Related Child Applications (1)

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JP2014205471A Division JP6228096B2 (ja) 2007-04-03 2014-10-06 分子のグリコシル化

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JP2010523102A JP2010523102A (ja) 2010-07-15
JP2010523102A5 JP2010523102A5 (enExample) 2011-05-19
JP5967861B2 true JP5967861B2 (ja) 2016-08-10

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JP2010501617A Expired - Fee Related JP5967861B2 (ja) 2007-04-03 2008-04-03 分子のグリコシル化
JP2014205471A Expired - Fee Related JP6228096B2 (ja) 2007-04-03 2014-10-06 分子のグリコシル化
JP2017000348A Expired - Fee Related JP6511476B2 (ja) 2007-04-03 2017-01-05 分子のグリコシル化

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JP2017000348A Expired - Fee Related JP6511476B2 (ja) 2007-04-03 2017-01-05 分子のグリコシル化

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US (5) US8026083B2 (enExample)
EP (4) EP2508613A3 (enExample)
JP (3) JP5967861B2 (enExample)
KR (3) KR101811057B1 (enExample)
CN (2) CN104480140B (enExample)
CA (3) CA2887752C (enExample)
DK (2) DK2508612T3 (enExample)
SG (1) SG177941A1 (enExample)
WO (1) WO2008120107A2 (enExample)

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JP5990102B2 (ja) 2009-09-29 2016-09-07 ユニフェルシテイト ヘント ホスホ−６−マンノースへのマンノース−１−ホスホ−６−マンノース結合の加水分解
BR112012011980A2 (pt) 2009-11-19 2021-09-08 Oxyrane Uk Limited Métodos de produzir células transformadas de yarrowia lipolytica e proteínas-alvocompreendendo n-glicanos, células transformadas de yarrowia lipolytica e suas culturas, bem como composição compreendendo glicoproteínas
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