JP5967756B2 - 分光用基板 - Google Patents
分光用基板 Download PDFInfo
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- JP5967756B2 JP5967756B2 JP2012103029A JP2012103029A JP5967756B2 JP 5967756 B2 JP5967756 B2 JP 5967756B2 JP 2012103029 A JP2012103029 A JP 2012103029A JP 2012103029 A JP2012103029 A JP 2012103029A JP 5967756 B2 JP5967756 B2 JP 5967756B2
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- Investigating Or Analysing Materials By Optical Means (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Description
(実施例1)
図2は、分光用基板の具体的な作製方法を示す。まず、基板としてガラス基板11を用い、ガラス基板11の上に微粒子としてシリカナノ粒子12を吸着させる。このために、ガラス基板11表面の化学修飾を行う。アミノプロピルトリメトキシシランもしくはアミノプロピルトリエトキシシラン等のシランカップリング試薬の水溶液を重量比で0.1%〜10%のものを用意し、ガラス基板11を水溶液中に10秒から1分の間浸漬する。
次に、被検体及び溶媒が油性物質の場合の分光用基板の作製例を以下に示す。水と油とは混ざらない性質があるので、分光測定領域となる表面増強領域を疎水性、表面増強領域以外の周辺の領域を親水性にすることで、油性サンプルを滴下すると、サンプルは球状の液滴を形成する。
2 微粒子
3 金属層
4 金属層
10 金属付着微粒子
13 シラン分子
14 シラン分子
15 チオール分子
Claims (4)
- 基板上に吸着された疎水性又は親水性を有する微粒子群と、分光測定領域のみ前記各微粒子の表面に形成された表面増強用の第1の金属層とを備え、前記分光測定領域以外の前記基板表面には前記疎水性又は親水性を有する微粒子が配置されていることを特徴とする分光用基板。
- 前記疎水性又は親水性を有する微粒子は、シランカップリング処理が施されていることを特徴とする請求項1に記載の分光用基板。
- 前記微粒子群の各微粒子は、粒径5nm〜1000nmのシリカ、酸化チタン、ポリスチレンのいずれかの材料で構成されていることを特徴とする請求項1又は請求項2に記載の分光用基板。
- 前記第1の金属層は、膜厚5nm〜1000nmの銀あるいは金で構成されていることを特徴とする請求項1〜請求項3のいずれか1項に記載の分光用基板。
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JP2012103029A JP5967756B2 (ja) | 2012-04-27 | 2012-04-27 | 分光用基板 |
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JP2012103029A JP5967756B2 (ja) | 2012-04-27 | 2012-04-27 | 分光用基板 |
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JP2013231641A JP2013231641A (ja) | 2013-11-14 |
JP5967756B2 true JP5967756B2 (ja) | 2016-08-10 |
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JP2012103029A Expired - Fee Related JP5967756B2 (ja) | 2012-04-27 | 2012-04-27 | 分光用基板 |
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Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6337127B2 (ja) * | 2014-08-27 | 2018-06-06 | 富士フイルム株式会社 | 光電場増強デバイスおよび光電場増強デバイスの製造方法 |
CN105424677B (zh) * | 2015-12-02 | 2018-01-12 | 公安部上海消防研究所 | 基于表面增强拉曼光谱检测火灾现场残留有机物的方法 |
CN105499602B (zh) * | 2015-12-21 | 2018-11-16 | 上海交通大学 | 一种基于还原法合成金纳米颗粒的sers基底制备方法 |
WO2017171087A1 (ja) * | 2016-03-31 | 2017-10-05 | 積水化成品工業株式会社 | 金属被覆異形樹脂粒子及びその製造方法、金属被覆異形樹脂粒子の配列膜及びその製造方法、粒子群、並びに粒子配列膜の製造方法 |
CN109856116B (zh) * | 2019-02-28 | 2021-06-29 | 吉林大学 | 一种利用表面增强拉曼散射原位监测化学反应的分级纳米锥阵列及其制备方法 |
KR102274582B1 (ko) * | 2019-12-27 | 2021-07-08 | (주)광림정공 | 국부적 친수성을 지닌 표면증강 라만산란기판 및 그 제조방법 |
JPWO2022123968A1 (ja) * | 2020-12-07 | 2022-06-16 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
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JP2003042947A (ja) * | 2001-07-31 | 2003-02-13 | Mitsubishi Chemicals Corp | 表面プラズモン共鳴セル及びそれを利用した試料流体の分析方法 |
JP2005144569A (ja) * | 2003-11-12 | 2005-06-09 | Hitachi Ltd | 二次元配列構造体基板および該基板から剥離した微粒子 |
JP4418705B2 (ja) * | 2004-04-27 | 2010-02-24 | 富士フイルム株式会社 | バイオセンサー |
JP2006047153A (ja) * | 2004-08-05 | 2006-02-16 | Sony Corp | Dnaチップの製造方法と製造システム、ハイブリダイゼーション検出方法と検出システム、並びに基板処理装置と基板処理方法 |
EP1715326A1 (en) * | 2005-04-22 | 2006-10-25 | Universität Heidelberg | Sensor chip with connected non-metallic particles comprising a metallic coating |
JP5500571B2 (ja) * | 2009-03-26 | 2014-05-21 | 株式会社ニデック | 試験片,該試験片の製造方法 |
JP5494954B2 (ja) * | 2010-03-29 | 2014-05-21 | 学校法人 東洋大学 | 分析用基板及びその製造方法 |
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