JP5965927B2 - デコリン組成物およびその使用 - Google Patents

デコリン組成物およびその使用 Download PDF

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Publication number
JP5965927B2
JP5965927B2 JP2013558110A JP2013558110A JP5965927B2 JP 5965927 B2 JP5965927 B2 JP 5965927B2 JP 2013558110 A JP2013558110 A JP 2013558110A JP 2013558110 A JP2013558110 A JP 2013558110A JP 5965927 B2 JP5965927 B2 JP 5965927B2
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Prior art keywords
decorin
medium
core protein
cell
gag
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JP2013558110A
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Japanese (ja)
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JP2014518508A5 (enExample
JP2014518508A (ja
Inventor
トーマス ブレック，グレゴリー
トーマス ブレック，グレゴリー
ジョン コリンズ，イアン
ジョン コリンズ，イアン
ジョセフ フライ，マーク
ジョセフ フライ，マーク
Original Assignee
キャタレント ファーマ ソリューションズ リミテッド ライアビリティ カンパニー
キャタレント ファーマ ソリューションズ リミテッド ライアビリティ カンパニー
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4725—Proteoglycans, e.g. aggreccan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2013558110A 2011-03-14 2012-03-13 デコリン組成物およびその使用 Active JP5965927B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161452299P 2011-03-14 2011-03-14
US61/452,299 2011-03-14
PCT/US2012/028911 WO2012125626A2 (en) 2011-03-14 2012-03-13 Decorin compositions and use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016082308A Division JP2016185952A (ja) 2011-03-14 2016-04-15 デコリン組成物およびその使用

Publications (3)

Publication Number Publication Date
JP2014518508A JP2014518508A (ja) 2014-07-31
JP2014518508A5 JP2014518508A5 (enExample) 2014-09-11
JP5965927B2 true JP5965927B2 (ja) 2016-08-10

Family

ID=46828968

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2013558110A Active JP5965927B2 (ja) 2011-03-14 2012-03-13 デコリン組成物およびその使用
JP2016082308A Pending JP2016185952A (ja) 2011-03-14 2016-04-15 デコリン組成物およびその使用
JP2018146607A Active JP6831813B2 (ja) 2011-03-14 2018-08-03 デコリン組成物およびその使用

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2016082308A Pending JP2016185952A (ja) 2011-03-14 2016-04-15 デコリン組成物およびその使用
JP2018146607A Active JP6831813B2 (ja) 2011-03-14 2018-08-03 デコリン組成物およびその使用

Country Status (6)

Country Link
US (2) US20120238727A1 (enExample)
EP (2) EP2686335B1 (enExample)
JP (3) JP5965927B2 (enExample)
CN (1) CN103917655B (enExample)
DK (1) DK2686335T3 (enExample)
WO (1) WO2012125626A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2014257267B2 (en) * 2013-04-22 2017-03-16 Catalent Pharma Solutions, Llc Veterinary decorin compositions and use thereof
AU2014265632B2 (en) 2013-05-14 2019-09-19 Medimmune, Llc Synthetic oligosaccharide subunits of the psl exopolysaccharide of pseudomonas aeruginosa and uses thereof
JP2018048053A (ja) 2016-09-23 2018-03-29 昭和電工株式会社 ＳｉＣ単結晶成長用坩堝
US11377488B2 (en) * 2018-07-03 2022-07-05 Catalent Pharma Solutions, Llc Multifunctional protein molecules comprising decorin and use thereof
US11725043B2 (en) 2020-03-05 2023-08-15 DiaMedica USA Inc. Ulinastatin polypeptides

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6509314B1 (en) * 1988-06-28 2003-01-21 The Burnham Institute Methods of preventing or reducing scarring with decorin or biglycan
JP2887325B2 (ja) * 1988-06-28 1999-04-26 ラ ホヤ キャンサー リサーチ ファウンデーション デコリンによる細胞増殖の抑制
US5654270A (en) * 1988-06-28 1997-08-05 La Jolla Cancer Research Foundation Use of fibromodulin to prevent or reduce dermal scarring
JPH07504886A (ja) * 1991-11-14 1995-06-01 ラ　ホヤ　キャンサー　リサーチ　ファウンデーション 細胞調節因子のインヒビターおよびはん痕形成を予防または緩和する方法
FI944575A7 (fi) * 1992-04-03 1994-11-29 La Jolla Cancer Res Foundation Dekoriinigragmentteja ja menetelmiä solunsäätelytekijöiden inhiboimise ksi
US5567807A (en) * 1994-07-08 1996-10-22 La Jolla Cancer Research Foundation Processes for the purification of human recombinant decorin and the detection of guanidinium ions
AU2001259465B2 (en) * 2000-05-05 2006-12-07 Gtc Biotherapeutics, Inc. Transgenically produced decorin
US6852510B2 (en) 2000-07-03 2005-02-08 Gala Design Inc Host cells containing multiple integrating vectors
US20030224415A1 (en) 2001-06-29 2003-12-04 Gala Design, Inc. Selection free growth of host cells containing multiple integrating vectors
US20040235173A1 (en) 2000-07-03 2004-11-25 Gala Design, Inc. Production of host cells containing multiple integrating vectors by serial transduction
US20030124152A1 (en) * 2001-11-02 2003-07-03 Pang Danny Zhong Der Use of decorin in a cosmetic or dermatologic composition
KR100495126B1 (ko) * 2002-04-16 2005-06-14 한국생명공학연구원 Ｎ-아세틸갈락토스아미닐트랜스퍼라제 활성을 갖는 융합 단백질, 이를 코딩하는 유전자 및 상기 유전자가 도입된 형질전환 세포주
US8258269B2 (en) * 2007-03-23 2012-09-04 Asahi Kasei Pharma Corporation Method for producing high-purity soluble thrombomodulin
US8945895B2 (en) * 2009-07-31 2015-02-03 Baxter International Inc. Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof

Also Published As

Publication number Publication date
EP2686335A2 (en) 2014-01-22
CN103917655B (zh) 2016-05-25
DK2686335T3 (en) 2018-07-30
WO2012125626A3 (en) 2014-04-24
US20220073579A1 (en) 2022-03-10
US20120238727A1 (en) 2012-09-20
EP3456837A3 (en) 2019-04-24
WO2012125626A2 (en) 2012-09-20
EP2686335B1 (en) 2018-04-25
EP2686335A4 (en) 2015-11-25
JP2018191647A (ja) 2018-12-06
CN103917655A (zh) 2014-07-09
JP6831813B2 (ja) 2021-02-17
JP2014518508A (ja) 2014-07-31
EP3456837A2 (en) 2019-03-20
JP2016185952A (ja) 2016-10-27

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