JP5963207B2 - 上皮形成方法、ドレッシング、およびシステム - Google Patents
上皮形成方法、ドレッシング、およびシステム Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/90—Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
- A61M1/91—Suction aspects of the dressing
- A61M1/915—Constructional details of the pressure distribution manifold
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/00051—Accessories for dressings
- A61F13/00063—Accessories for dressings comprising medicaments or additives, e.g. odor control, PH control, debriding, antimicrobic
-
- A61F13/01021—
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A61F13/05—
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F2013/00089—Wound bandages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/04—Skin
Description
本発明は、35USC§119(e)下において、2010年3月16日出願の米国仮特許出願第61/314,236号(「Epithelialization Methods,Dressings,and Systems」)(あらゆる点において本願明細書に援用する)、および2010年3月16日出願の米国仮特許出願第61/314,274号(「Patterned Neo−Epithelialization Dressings,Systems,and Methods」)(これも、あらゆる点において本願明細書に援用する)の出願の利益を主張する。
Claims (20)
- 新生上皮組織と、隣接する組織層との間にアンカー点を形成する上皮形成ドレッシングにおいて、
第1の側面と第2の組織面側面とを有するドレッシング本体;
近位端部と遠位端部とをそれぞれ有する複数の突起であって、各遠位端部が複数の細孔を有し、各近位端部が前記ドレッシング本体の前記第2の組織面側面に結合されており、および各突起の縦方向長さが、10〜5000ミクロンの範囲にある、複数の突起;
前記ドレッシング本体の前記第1の側面および前記第2の組織面側面を通って配置された複数のアパーチャであって、前記複数の突起が前記複数のアパーチャの間に配置される、複数のアパーチャ;および
前記複数の突起の各々の前記遠位端部に形成されたサブ構造
を含むことを特徴とする、上皮形成ドレッシング。 - 請求項1に記載の上皮形成ドレッシングにおいて、前記サブ構造が、前記複数の突起の各突起の前記遠位端部に形成された溝を含むことを特徴とする、上皮形成ドレッシング。
- 請求項1に記載の上皮形成ドレッシングにおいて、前記サブ構造が、前記複数の突起の各突起の前記遠位端部に形成された複数の隆起を含むことを特徴とする、上皮形成ドレッシング。
- 請求項1に記載の上皮形成ドレッシングにおいて、前記サブ構造が、前記複数の突起の各突起の前記遠位端部に形成された波形を含むことを特徴とする、上皮形成ドレッシング。
- 請求項1または請求項2〜4のいずれか一項に記載の上皮形成ドレッシングにおいて、前記複数のアパーチャが複数のスリットを含むことを特徴とする、上皮形成ドレッシング。
- 請求項1または請求項2〜5のいずれか一項に記載の上皮形成ドレッシングにおいて、各突起が、内部部分と外部部分とを有し、および前記細孔が、前記内部部分と前記外部部分との間に流体連通をもたらすことを特徴とする、上皮形成ドレッシング。
- 請求項1または請求項2〜4のいずれか一項に記載の上皮形成ドレッシングにおいて、前記複数の突起が複数の円錐状の突起を含むことを特徴とする、上皮形成ドレッシング。
- 請求項1または請求項2〜7のいずれか一項に記載の上皮形成ドレッシングにおいて、前記複数の突起が、前記突起の内部部分に形成された供給溜めをさらに含むことを特徴とする、上皮形成ドレッシング。
- 請求項1または請求項2〜8のいずれか一項に記載の上皮形成ドレッシングにおいて、前記複数の突起が、前記突起の内部部分に形成された供給溜めをさらに含み、および前記供給溜めが可溶性因子を含むことを特徴とする、上皮形成ドレッシング。
- 請求項1または請求項2〜8のいずれか一項に記載の上皮形成ドレッシングにおいて、前記複数の突起が、前記突起の内部部分に形成された供給溜めをさらに含み、および前記複数の突起および前記ドレッシング本体が生体再吸収性材料で形成されていることを特徴とする、上皮形成ドレッシング。
- 創傷の上皮形成を促進するシステムにおいて、
上皮形成ドレッシングにおいて、
第1の側面と第2の組織面側面とを有するドレッシング本体、
近位端部と遠位端部とをそれぞれ含む複数の突起であって、前記遠位端部が複数の細孔を有し、前記近位端部が前記ドレッシング本体の前記第2の組織面側面に結合されている、複数の突起、
前記ドレッシング本体の前記第1の側面および前記第2の組織面側面を通って配置された複数のアパーチャであって、前記複数の突起が前記複数のアパーチャの間に配置される、複数のアパーチャ、
を含む上皮形成ドレッシング;
前記創傷および前記上皮形成ドレッシングを覆って流体シールを形成するシール部材;
前記上皮形成ドレッシングに減圧を提供する減圧インターフェース;および
前記減圧インターフェースに流体結合されるよう構成された減圧源
を含むことを特徴とする、システム。 - 請求項11に記載の創傷の上皮形成を促進するシステムにおいて、前記突起の前記遠位端部に形成されたサブ構造を更に含み、前記サブ構造が、溝を含むことを特徴とする、システム。
- 請求項11に記載の創傷の上皮形成を促進するシステムにおいて、前記突起の前記遠位端部に形成されたサブ構造を更に含み、前記サブ構造が、複数の隆起を含むことを特徴とする、システム。
- 請求項11または12または13に記載の創傷の上皮形成を促進するシステムにおいて、前記複数のアパーチャが複数のスリットを含むことを特徴とする、システム。
- 請求項11〜14のいずれか一項に記載の創傷の上皮形成を促進するシステムにおいて、前記複数の突起が複数の円錐状の突起を含むことを特徴とする、システム。
- 請求項11または請求項12〜15のいずれか一項に記載の創傷の上皮形成を促進するシステムにおいて、前記複数の突起が、前記突起の内部部分に形成された供給溜めをさらに含むことを特徴とする、システム。
- 請求項11または請求項12〜15のいずれか一項に記載の創傷の上皮形成を促進するシステムにおいて、前記複数の突起が、前記突起の内部部分に形成された供給溜めをさらに含み、および前記供給溜めが可溶性因子を含むことを特徴とする、システム。
- 請求項11または請求項12〜15のいずれか一項に記載の創傷の上皮形成を促進するシステムにおいて、前記複数の突起が、前記突起の内部部分に形成された供給溜めをさらに含み、および前記複数の突起および前記ドレッシング本体が生体再吸収性材料で形成されていることを特徴とする、システム。
- 上皮形成ドレッシングの製造方法において、
医療グレードのポリマーから、第1の側面と第2の側面とを有するドレッシング本体を形成するステップと;
医療グレードのポリマーから複数の突起を形成するステップにおいて、前記突起が、内部部分と、前記突起の前記内部部分と外部部分とを流体的に結合する複数の細孔とを有して形成されるステップと;
前記ドレッシング本体の前記第2の側面に前記複数の突起を結合させるステップと;
前記複数の突起の間で前記ドレッシング本体にアパーチャを形成するステップと
を含むことを特徴とする、方法。 - 請求項19に記載の製造方法において、ドレッシング本体を形成する前記ステップ、複数の突起を形成する前記ステップ、および前記複数の突起を結合させる前記ステップが、前記複数の突起を備える前記ドレッシング本体を成形することを含むことを特徴とする、方法。
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31427410P | 2010-03-16 | 2010-03-16 | |
US31423610P | 2010-03-16 | 2010-03-16 | |
US61/314,274 | 2010-03-16 | ||
US61/314,236 | 2010-03-16 | ||
US13/045,663 US8808258B2 (en) | 2010-03-16 | 2011-03-11 | Epithelialization methods, dressings, and systems |
US13/045,663 | 2011-03-11 | ||
PCT/US2011/028352 WO2011115911A1 (en) | 2010-03-16 | 2011-03-14 | Epithelialization methods, dressings, and systems |
Publications (3)
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JP2013521940A JP2013521940A (ja) | 2013-06-13 |
JP2013521940A5 JP2013521940A5 (ja) | 2014-05-15 |
JP5963207B2 true JP5963207B2 (ja) | 2016-08-03 |
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JP2013500111A Expired - Fee Related JP5968867B2 (ja) | 2010-03-16 | 2011-03-11 | パターン化された新生上皮形成ドレッシング、システム、および方法 |
JP2013500126A Expired - Fee Related JP5963207B2 (ja) | 2010-03-16 | 2011-03-14 | 上皮形成方法、ドレッシング、およびシステム |
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Country Status (8)
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US (6) | US9358158B2 (ja) |
EP (3) | EP2547301B1 (ja) |
JP (2) | JP5968867B2 (ja) |
CN (2) | CN102781382B (ja) |
AU (2) | AU2011227598B2 (ja) |
CA (2) | CA2790413C (ja) |
TW (1) | TW201138878A (ja) |
WO (2) | WO2011115851A1 (ja) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0808376D0 (en) | 2008-05-08 | 2008-06-18 | Bristol Myers Squibb Co | Wound dressing |
GB0817796D0 (en) | 2008-09-29 | 2008-11-05 | Convatec Inc | wound dressing |
US8690844B2 (en) * | 2009-08-27 | 2014-04-08 | Kci Licensing, Inc. | Re-epithelialization wound dressings and systems |
US20110054420A1 (en) * | 2009-08-27 | 2011-03-03 | Christopher Brian Locke | Reduced-pressure wound dressings and systems for re-epithelialization and granulation |
US9358158B2 (en) * | 2010-03-16 | 2016-06-07 | Kci Licensing, Inc. | Patterned neo-epithelialization dressings, systems, and methods |
US8790699B2 (en) * | 2010-04-23 | 2014-07-29 | Warsaw Orthpedic, Inc. | Foam-formed collagen strand |
GB201015656D0 (en) | 2010-09-20 | 2010-10-27 | Smith & Nephew | Pressure control apparatus |
GB201020236D0 (en) | 2010-11-30 | 2011-01-12 | Convatec Technologies Inc | A composition for detecting biofilms on viable tissues |
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