JP5927506B2 - １−メチル−２’，６’−ピペコロキシリダイドの皮膚医薬組成物および使用方法 - Google Patents

１−メチル−２’，６’−ピペコロキシリダイドの皮膚医薬組成物および使用方法 Download PDF

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JP5927506B2
JP5927506B2 JP2013505118A JP2013505118A JP5927506B2 JP 5927506 B2 JP5927506 B2 JP 5927506B2 JP 2013505118 A JP2013505118 A JP 2013505118A JP 2013505118 A JP2013505118 A JP 2013505118A JP 5927506 B2 JP5927506 B2 JP 5927506B2
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pain
mepivacaine
dosage form
skin
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JP2013523893A5 (cg-RX-API-DMAC7.html
JP2013523893A (ja
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バブル、ナジブ
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レルマダ セラピューティクス、インク．
レルマダ セラピューティクス、インク．
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4458—Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
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    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
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    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A—HUMAN NECESSITIES
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dispersion Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2013505118A 2010-04-13 2011-04-13 １−メチル−２’，６’−ピペコロキシリダイドの皮膚医薬組成物および使用方法 Active JP5927506B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32378010P 2010-04-13 2010-04-13
US61/323,780 2010-04-13
PCT/US2011/032381 WO2011130455A1 (en) 2010-04-13 2011-04-13 Dermal pharmaceutical compositions of 1-methyl-2',6'-pipecoloxylidide and method of use

Publications (3)

Publication Number Publication Date
JP2013523893A JP2013523893A (ja) 2013-06-17
JP2013523893A5 JP2013523893A5 (cg-RX-API-DMAC7.html) 2014-06-19
JP5927506B2 true JP5927506B2 (ja) 2016-06-01

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US (1) US11607407B2 (cg-RX-API-DMAC7.html)
EP (1) EP2557924B1 (cg-RX-API-DMAC7.html)
JP (1) JP5927506B2 (cg-RX-API-DMAC7.html)
KR (3) KR20150036825A (cg-RX-API-DMAC7.html)
CN (2) CN103491778B (cg-RX-API-DMAC7.html)
AU (1) AU2011239636A1 (cg-RX-API-DMAC7.html)
CA (1) CA2796575C (cg-RX-API-DMAC7.html)
DK (1) DK2557924T3 (cg-RX-API-DMAC7.html)
WO (1) WO2011130455A1 (cg-RX-API-DMAC7.html)

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EP2921184A1 (de) * 2014-03-19 2015-09-23 LTS LOHMANN Therapie-Systeme AG Überpflaster mit verbesserter Verträglichkeit und einer langen Haftungsdauer und Verfahren zu seiner Herstellung
CN104107210B (zh) * 2014-05-21 2017-11-17 安徽康缘药业有限公司 一种抗疲劳微乳液及其制备方法
CN105902494A (zh) * 2016-06-07 2016-08-31 东莞市麦亘生物科技有限公司 一种新型气冷喷雾剂及其使用方法
JP6801554B2 (ja) * 2017-03-29 2020-12-16 東洋インキＳｃホールディングス株式会社 皮膚貼付用粘着剤、皮膚用貼付剤、および剥離用シート状部材付き皮膚用貼付剤の製造方法
CA3072016C (en) * 2017-08-10 2022-06-14 Avro Life Sciences, Inc. Transdermal drug delivery system
KR20200102978A (ko) * 2017-12-26 2020-09-01 히로타로 후쿠오카 증모, 두피 혹은 피부의 개질, 창상 치유, 뼈 형성 촉진, 또는 모발의 개질에 이용하기 위한 의약 조성물
WO2022007917A1 (zh) * 2020-07-10 2022-01-13 江苏恒瑞医药股份有限公司 一种含麻醉药物活性成分的透皮制剂及其制备方法
CN112915072A (zh) * 2021-03-31 2021-06-08 重庆彭铿生物科技有限公司 一种用于骨质增生的膏药
EP4320204A1 (en) * 2021-04-09 2024-02-14 Dow Silicones Corporation Process for preparing a solventless polyorganosiloxane pellet and a waterborne dispersion of a silicone pressure sensitive adhesive base
WO2024062423A1 (en) * 2022-09-21 2024-03-28 Masek Josef Oromucosal film compositions
WO2025175174A1 (en) * 2024-02-14 2025-08-21 The Children's Medical Center Corporation 2'-6'-pipecoloxylidide as a sensory-selective anesthetic

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EP2557924B1 (en) 2019-06-12
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AU2011239636A1 (en) 2012-11-22
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CA2796575A1 (en) 2011-10-20
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