JP5921235B2 - ３−ヒドロキシ−６Ｈ−ベンゾ［ｃ］クロメン−６−オン誘導体およびその製造方法 - Google Patents

３−ヒドロキシ−６Ｈ−ベンゾ［ｃ］クロメン−６−オン誘導体およびその製造方法 Download PDF

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Publication number
JP5921235B2
JP5921235B2 JP2012024721A JP2012024721A JP5921235B2 JP 5921235 B2 JP5921235 B2 JP 5921235B2 JP 2012024721 A JP2012024721 A JP 2012024721A JP 2012024721 A JP2012024721 A JP 2012024721A JP 5921235 B2 JP5921235 B2 JP 5921235B2
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group
salt
formula
hydrogen atom
carbonate
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Japanese (ja)
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JP2012180345A (ja
JP2012180345A5 (enExample
Inventor
一弘 工藤
一弘 工藤
悟功 山本
悟功 山本
正和 伴
正和 伴
敦嗣 大野
敦嗣 大野
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Ayumi Pharmaceutical Corp
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Ayumi Pharmaceutical Corp
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
JP2012024721A 2011-02-09 2012-02-08 ３−ヒドロキシ−６Ｈ−ベンゾ［ｃ］クロメン−６−オン誘導体およびその製造方法 Expired - Fee Related JP5921235B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2012024721A JP5921235B2 (ja) 2011-02-09 2012-02-08 ３−ヒドロキシ−６Ｈ−ベンゾ［ｃ］クロメン−６−オン誘導体およびその製造方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2011026188 2011-02-09
JP2011026188 2011-02-09
JP2012024721A JP5921235B2 (ja) 2011-02-09 2012-02-08 ３−ヒドロキシ−６Ｈ−ベンゾ［ｃ］クロメン−６−オン誘導体およびその製造方法

Publications (3)

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JP2012180345A JP2012180345A (ja) 2012-09-20
JP2012180345A5 JP2012180345A5 (enExample) 2015-03-12
JP5921235B2 true JP5921235B2 (ja) 2016-05-24

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JP2012024721A Expired - Fee Related JP5921235B2 (ja) 2011-02-09 2012-02-08 ３−ヒドロキシ−６Ｈ−ベンゾ［ｃ］クロメン−６−オン誘導体およびその製造方法

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US (2) US8802869B2 (enExample)
EP (1) EP2674422A4 (enExample)
JP (1) JP5921235B2 (enExample)
KR (1) KR20140002735A (enExample)
CN (1) CN103370310A (enExample)
CA (1) CA2826871A1 (enExample)
TW (1) TW201309663A (enExample)
WO (1) WO2012108455A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012112791A1 (en) 2011-02-16 2012-08-23 Paloma Pharmaceuticals, Inc. Radiation countermeasure agents
US9394269B2 (en) 2013-12-23 2016-07-19 Amazentis Sa Process-scale synthesis of urolithins
WO2015154047A1 (en) * 2014-04-03 2015-10-08 Restorgenex Corporation Novel methods
CN105884739B (zh) * 2016-04-14 2018-04-27 广西大学 一种苯并香豆素多环化合物的合成方法
EP3639854A4 (en) 2017-06-16 2021-03-03 The Doshisha MTOR INHIBITIVE MEDICINAL PRODUCT FOR THE TREATMENT OR PREVENTION OF OPHTHALMIC SYMPTOMS, DISORDERS, OR DISEASES AND USE THEREOF
US20200121652A1 (en) 2017-06-16 2020-04-23 The Doshisha Compounds having caspase inhibitory activity, pharmaceutical agent containing said compounds and for treating or preventing corneal endothelial symptoms, disorders, or diseases, and application of said pharmaceutical agent
CN112074510A (zh) * 2018-02-27 2020-12-11 阿马曾提斯公司 尿石素a的工业规模合成
CN111039913A (zh) * 2018-10-15 2020-04-21 韦忠友 一种具有抗肿瘤作用的化合物的制备方法
AU2022212883A1 (en) 2021-01-27 2023-08-17 Vandria Sa Urolithin derivatives and methods of use thereof
WO2024091983A1 (en) 2022-10-25 2024-05-02 Artus Therapeutics, Inc. Therapeutic agents for enhancing epithelial and/or endothelial barrier function
CN119661547A (zh) * 2023-09-20 2025-03-21 科辉智药(深圳)新药研究中心有限公司 作为sarm1酶活性抑制剂的三环吡啶类化合物及其应用
CN117756766A (zh) * 2023-12-20 2024-03-26 常州大学 3-羟基-8-氟-6H-苯并[c]色烯-6-酮类衍生物及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004073612A2 (en) * 2003-02-13 2004-09-02 Merck & Co. Inc. Estrogen receptor modulators
US20050282781A1 (en) * 2004-06-18 2005-12-22 Shibnath Ghosal Compositions of stable bioactive metabolites of docosahexaenoic (DHA) and eicosapentaenoic (EPA) acids
CA2621292C (en) 2005-09-14 2014-05-27 Santen Pharmaceutical Co., Ltd. 1-2-dihydroquinoline derivative having glucocorticoid receptor binding actvity
PL2085387T3 (pl) 2006-11-14 2013-09-30 Ayumi Pharmaceutical Corp Nowe pochodne 1,2-dihydrochinoliny zawierające jako podstawniki fenylochalkogeno-podstawioną niższą grupę alkilową oraz wprowadzoną przez ester grupę fenylową
GEP20146061B (en) * 2008-05-12 2014-03-25 Santen Pharmaceutical Co Ltd Glucocorticoid receptor agonist composed of 2,2,4-trimethyl-6-phenyl- 1,2-dihydroquinoline derivative having substituted oxy group

Also Published As

Publication number Publication date
CN103370310A (zh) 2013-10-23
US8802869B2 (en) 2014-08-12
EP2674422A1 (en) 2013-12-18
JP2012180345A (ja) 2012-09-20
WO2012108455A1 (ja) 2012-08-16
TW201309663A (zh) 2013-03-01
US20140296540A1 (en) 2014-10-02
US20130310576A1 (en) 2013-11-21
CA2826871A1 (en) 2012-08-16
EP2674422A4 (en) 2015-01-21
KR20140002735A (ko) 2014-01-08
US9029572B2 (en) 2015-05-12

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