JP5908402B2 - 腎疾患の予防方法およびその症状を処置する方法 - Google Patents

腎疾患の予防方法およびその症状を処置する方法 Download PDF

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Publication number
JP5908402B2
JP5908402B2 JP2012523654A JP2012523654A JP5908402B2 JP 5908402 B2 JP5908402 B2 JP 5908402B2 JP 2012523654 A JP2012523654 A JP 2012523654A JP 2012523654 A JP2012523654 A JP 2012523654A JP 5908402 B2 JP5908402 B2 JP 5908402B2
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disease
renal
kidney
proteinuria
drug
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Japanese (ja)
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JP2013501049A5 (enExample
JP2013501049A (ja
Inventor
マーガレット、クラゲット‐デイム
ローリー、プラム
ヘクター、エフ．デルーカ
キム、ジェームズ、ウォンキー
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Wisconsin Alumni Research Foundation
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Wisconsin Alumni Research Foundation
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2012523654A 2009-08-03 2010-07-28 腎疾患の予防方法およびその症状を処置する方法 Active JP5908402B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US23086109P 2009-08-03 2009-08-03
US61/230,861 2009-08-03
US25366709P 2009-10-21 2009-10-21
US61/253,667 2009-10-21
PCT/US2010/043551 WO2011017165A1 (en) 2009-08-03 2010-07-28 Method of preventing renal disease and treating symptoms thereof

Publications (3)

Publication Number Publication Date
JP2013501049A JP2013501049A (ja) 2013-01-10
JP2013501049A5 JP2013501049A5 (enExample) 2013-09-12
JP5908402B2 true JP5908402B2 (ja) 2016-04-26

Family

ID=42983794

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012523654A Active JP5908402B2 (ja) 2009-08-03 2010-07-28 腎疾患の予防方法およびその症状を処置する方法

Country Status (7)

Country Link
US (1) US20110034426A1 (enExample)
EP (1) EP2461815B1 (enExample)
JP (1) JP5908402B2 (enExample)
AU (1) AU2010281391B2 (enExample)
CA (1) CA2764577C (enExample)
ES (1) ES2524335T3 (enExample)
WO (1) WO2011017165A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110237557A1 (en) * 2010-03-23 2011-09-29 Deluca Hector F Diastereomers of 2-methylene-19-nor-22-methyl-1alpha,25-dihydroxyvitamin d3
US8664206B2 (en) 2010-03-23 2014-03-04 Wisconsin Alumni Research Foundation Diastereomers of 2-methylene-19-nor-22-methyl-1α,25-dihydroxyvitamin D3
US8604009B2 (en) * 2010-03-23 2013-12-10 Wisconsin Alumni Research Foundation (20S)-2-methylene-19-nor-22-dimethyl-1α,25-dihydroxyvitamin D3 and (20R)-2-methylene-19-nor-22-dimethyl-1α,25-hydroxyvitamin D3
HK1206600A1 (en) * 2012-06-29 2016-01-15 Wisconsin Alumni Research Foundation USE OF 2-METHYLENE-19-NOR-(20S)-1α,25-DIHYDROXYVITAMIN D3 TO TREAT SECONDARY HYPERPARATHYROIDISM
US10369161B2 (en) 2014-12-30 2019-08-06 Wisconsin Alumni Research Foundation Use of 2-methylene-19-NOR-(20S)-1-alpha,25-dihydroxyvitamin D3 to treat primary hyperparathyroidism
US9539264B2 (en) 2014-12-30 2017-01-10 Wisconsin Alumni Research Foundation Use of 2-methylene-19-nor-(20S)-1-alpha,25-dihydroxyvitamin D3 to treat secondary hyperparathyroidism in patients previously treated with calcimimetics
WO2017184262A1 (en) * 2016-04-18 2017-10-26 Wisconsin Alumni Research Foundation Use of 2amd and 2md to treat fibrosis

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843928A (en) 1997-03-17 1998-12-01 Wisconsin Alumni Research Foundation 2-alkylidene-19-nor-vitamin D compounds
US6306844B1 (en) * 1997-03-17 2001-10-23 Wisconsin Alumni Research Foundation Use of 2α-methyl-19-nor-20(S)-1α, 25-dihydroxyvitamin D3 to increase bone strength
US6673782B2 (en) * 1999-04-29 2004-01-06 Wisconsin Alumni Research Foundation Treatment of systemic lupus erythematosis
AU2001247619A1 (en) * 2000-03-27 2001-10-08 Wisconsin Alumni Research Foundation Vitamin d compounds used to stabilize kidney transplants
EP1301189A2 (en) * 2000-07-14 2003-04-16 Wisconsin Alumni Research Foundation USE OF 2-METHYLENE-19-NOR-20(S)-1$g(a),25-DIHYDROXYVITAMIN D 3? TO INCREASE BONE STRENGTH
US20050124591A1 (en) * 2003-07-29 2005-06-09 Jin Tian Use of vitamin Ds to treat kidney disease
US20060171983A1 (en) * 2003-07-30 2006-08-03 Jin Tian Use of Vitamin D receptor activators or Vitamin D analogs to treat cardiovascular disease
US7704980B2 (en) * 2003-10-08 2010-04-27 Wisconsin Alumni Research Foundation Treatment of inflammatory bowel disease with 2-methylene-19-nor-vitamin D compounds
US7214671B2 (en) * 2004-02-19 2007-05-08 Wisconsin Alumni Research Foundation Use of 2-methylene-19-nor-20(S)-1α,25-dihydroxyvitamin D3 for the prophylaxis of bone diseases
CA2597624C (en) * 2005-02-11 2012-08-14 Wisconsin Alumni Research Foundation 2-methylene-19-nor-(20s-24s)-1.alpha.,25-dihydroxyvitamin-d2
ES3047207T3 (en) * 2007-04-25 2025-12-03 Opko Renal Llc Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease

Also Published As

Publication number Publication date
EP2461815A1 (en) 2012-06-13
AU2010281391B2 (en) 2015-05-07
WO2011017165A1 (en) 2011-02-10
AU2010281391A1 (en) 2011-12-22
EP2461815B1 (en) 2014-10-22
CA2764577C (en) 2017-12-19
US20110034426A1 (en) 2011-02-10
ES2524335T3 (es) 2014-12-05
JP2013501049A (ja) 2013-01-10
CA2764577A1 (en) 2011-02-10
WO2011017165A8 (en) 2011-09-15

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