AU2010281391B2 - Method of preventing renal disease and treating symptoms thereof - Google Patents
Method of preventing renal disease and treating symptoms thereof Download PDFInfo
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- AU2010281391B2 AU2010281391B2 AU2010281391A AU2010281391A AU2010281391B2 AU 2010281391 B2 AU2010281391 B2 AU 2010281391B2 AU 2010281391 A AU2010281391 A AU 2010281391A AU 2010281391 A AU2010281391 A AU 2010281391A AU 2010281391 B2 AU2010281391 B2 AU 2010281391B2
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23086109P | 2009-08-03 | 2009-08-03 | |
| US61/230,861 | 2009-08-03 | ||
| US25366709P | 2009-10-21 | 2009-10-21 | |
| US61/253,667 | 2009-10-21 | ||
| PCT/US2010/043551 WO2011017165A1 (en) | 2009-08-03 | 2010-07-28 | Method of preventing renal disease and treating symptoms thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2010281391A1 AU2010281391A1 (en) | 2011-12-22 |
| AU2010281391B2 true AU2010281391B2 (en) | 2015-05-07 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2010281391A Ceased AU2010281391B2 (en) | 2009-08-03 | 2010-07-28 | Method of preventing renal disease and treating symptoms thereof |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20110034426A1 (enExample) |
| EP (1) | EP2461815B1 (enExample) |
| JP (1) | JP5908402B2 (enExample) |
| AU (1) | AU2010281391B2 (enExample) |
| CA (1) | CA2764577C (enExample) |
| ES (1) | ES2524335T3 (enExample) |
| WO (1) | WO2011017165A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2556053B1 (en) * | 2010-03-23 | 2015-07-29 | Wisconsin Alumni Research Foundation | (20s)-2-methylene-19-nor-22-dimethyl-1alpha,25- dihydroxyvitamin d3 and (20r)-2-methylene-19-nor-22-dimethyl-1alpha,25-hydroxyvitamin d3 |
| JP5931845B2 (ja) * | 2010-03-23 | 2016-06-08 | ウイスコンシン アラムニ リサーチ ファンデーション | ２−メチレン−１９−ノル−２２−メチル−１α，２５−ジヒドロキシビタミンＤ３のジアステレオマー |
| US8664206B2 (en) | 2010-03-23 | 2014-03-04 | Wisconsin Alumni Research Foundation | Diastereomers of 2-methylene-19-nor-22-methyl-1α,25-dihydroxyvitamin D3 |
| EP2866811A1 (en) * | 2012-06-29 | 2015-05-06 | Wisconsin Alumni Research Foundation | USE OF 2-METHYLENE-19-NOR-(20S)-1 alpha,25-DIHYDROXYVITAMIN D³ TO TREAT SECONDARY HYPERPARATHYROIDISM |
| US9539264B2 (en) | 2014-12-30 | 2017-01-10 | Wisconsin Alumni Research Foundation | Use of 2-methylene-19-nor-(20S)-1-alpha,25-dihydroxyvitamin D3 to treat secondary hyperparathyroidism in patients previously treated with calcimimetics |
| US10369161B2 (en) | 2014-12-30 | 2019-08-06 | Wisconsin Alumni Research Foundation | Use of 2-methylene-19-NOR-(20S)-1-alpha,25-dihydroxyvitamin D3 to treat primary hyperparathyroidism |
| US20170296558A1 (en) * | 2016-04-18 | 2017-10-19 | Wisconsin Alumni Research Foundation | Use of 2amd and 2md to treat fibrosis |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020028830A1 (en) * | 1999-04-29 | 2002-03-07 | Deluca Hector F. | Treatment fo systemic lupus erythematosis |
| US20050187201A1 (en) * | 2004-02-19 | 2005-08-25 | Deluca Hector F. | Use of 2-methylene-19-nor-20(S)-1alpha,25-dihydroxyvitamin D3 for the prophylaxis of bone diseases |
| US20060003973A1 (en) * | 1997-03-17 | 2006-01-05 | Deluca Hector F | Use of 2alpha-methyl-19-nor-20(S)-1alpha,25-dihydroxyvitamin D3 to increase bone strength |
| US20060135492A1 (en) * | 2000-07-14 | 2006-06-22 | Wisconsin Alumni Research Foundation | Use of 2-methylene-19-nor-20(S)-1alpha,25-dihydroxyvitamin D3 to increase bone strength |
| US7563783B2 (en) * | 2005-02-11 | 2009-07-21 | Wisconsin Alumni Research Foundation | 2-methylene-19-nor-(20S-24S)-1α,25-dihydroxyvitamin-D2 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5843928A (en) * | 1997-03-17 | 1998-12-01 | Wisconsin Alumni Research Foundation | 2-alkylidene-19-nor-vitamin D compounds |
| EP1267886B1 (en) * | 2000-03-27 | 2006-03-08 | Wisconsin Alumni Research Foundation | Vitamin d compounds for the treatment of chronic allograft nephropathy in kidney transplant patients |
| US20050124591A1 (en) | 2003-07-29 | 2005-06-09 | Jin Tian | Use of vitamin Ds to treat kidney disease |
| US20060171983A1 (en) * | 2003-07-30 | 2006-08-03 | Jin Tian | Use of Vitamin D receptor activators or Vitamin D analogs to treat cardiovascular disease |
| US7704980B2 (en) * | 2003-10-08 | 2010-04-27 | Wisconsin Alumni Research Foundation | Treatment of inflammatory bowel disease with 2-methylene-19-nor-vitamin D compounds |
| EP3225243B1 (en) * | 2007-04-25 | 2025-09-03 | Opko Renal, LLC | Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease |
-
2010
- 2010-07-28 CA CA2764577A patent/CA2764577C/en not_active Expired - Fee Related
- 2010-07-28 WO PCT/US2010/043551 patent/WO2011017165A1/en not_active Ceased
- 2010-07-28 EP EP10744767.4A patent/EP2461815B1/en not_active Not-in-force
- 2010-07-28 JP JP2012523654A patent/JP5908402B2/ja active Active
- 2010-07-28 ES ES10744767.4T patent/ES2524335T3/es active Active
- 2010-07-28 US US12/845,173 patent/US20110034426A1/en not_active Abandoned
- 2010-07-28 AU AU2010281391A patent/AU2010281391B2/en not_active Ceased
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060003973A1 (en) * | 1997-03-17 | 2006-01-05 | Deluca Hector F | Use of 2alpha-methyl-19-nor-20(S)-1alpha,25-dihydroxyvitamin D3 to increase bone strength |
| US20020028830A1 (en) * | 1999-04-29 | 2002-03-07 | Deluca Hector F. | Treatment fo systemic lupus erythematosis |
| US20060135492A1 (en) * | 2000-07-14 | 2006-06-22 | Wisconsin Alumni Research Foundation | Use of 2-methylene-19-nor-20(S)-1alpha,25-dihydroxyvitamin D3 to increase bone strength |
| US20050187201A1 (en) * | 2004-02-19 | 2005-08-25 | Deluca Hector F. | Use of 2-methylene-19-nor-20(S)-1alpha,25-dihydroxyvitamin D3 for the prophylaxis of bone diseases |
| US7563783B2 (en) * | 2005-02-11 | 2009-07-21 | Wisconsin Alumni Research Foundation | 2-methylene-19-nor-(20S-24S)-1α,25-dihydroxyvitamin-D2 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2013501049A (ja) | 2013-01-10 |
| CA2764577C (en) | 2017-12-19 |
| ES2524335T3 (es) | 2014-12-05 |
| CA2764577A1 (en) | 2011-02-10 |
| WO2011017165A8 (en) | 2011-09-15 |
| EP2461815B1 (en) | 2014-10-22 |
| JP5908402B2 (ja) | 2016-04-26 |
| AU2010281391A1 (en) | 2011-12-22 |
| US20110034426A1 (en) | 2011-02-10 |
| EP2461815A1 (en) | 2012-06-13 |
| WO2011017165A1 (en) | 2011-02-10 |
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| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |