JP5902628B2 - 相乗的抗ウイルス組成物及びその使用 - Google Patents
相乗的抗ウイルス組成物及びその使用 Download PDFInfo
- Publication number
- JP5902628B2 JP5902628B2 JP2012545143A JP2012545143A JP5902628B2 JP 5902628 B2 JP5902628 B2 JP 5902628B2 JP 2012545143 A JP2012545143 A JP 2012545143A JP 2012545143 A JP2012545143 A JP 2012545143A JP 5902628 B2 JP5902628 B2 JP 5902628B2
- Authority
- JP
- Japan
- Prior art keywords
- carrageenan
- iota
- infection
- influenza virus
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
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- ZNOZWUKQPJXOIG-XSBHQQIPSA-L [(2r,3s,4r,5r,6s)-6-[[(1r,3s,4r,5r,8s)-3,4-dihydroxy-2,6-dioxabicyclo[3.2.1]octan-8-yl]oxy]-4-[[(1r,3r,4r,5r,8s)-8-[(2s,3r,4r,5r,6r)-3,4-dihydroxy-6-(hydroxymethyl)-5-sulfonatooxyoxan-2-yl]oxy-4-hydroxy-2,6-dioxabicyclo[3.2.1]octan-3-yl]oxy]-5-hydroxy-2-( Chemical compound O[C@@H]1[C@@H](O)[C@@H](OS([O-])(=O)=O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H]2OC[C@H]1O[C@H](O[C@H]1[C@H]([C@@H](CO)O[C@@H](O[C@@H]3[C@@H]4OC[C@H]3O[C@H](O)[C@@H]4O)[C@@H]1O)OS([O-])(=O)=O)[C@@H]2O ZNOZWUKQPJXOIG-XSBHQQIPSA-L 0.000 claims description 30
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/731—Carrageenans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Inorganic Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Otolaryngology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28214809P | 2009-12-22 | 2009-12-22 | |
| US61/282,148 | 2009-12-22 | ||
| PCT/EP2010/007726 WO2011076367A2 (en) | 2009-12-22 | 2010-12-17 | Synergistic antiviral composition and use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013515022A JP2013515022A (ja) | 2013-05-02 |
| JP2013515022A5 JP2013515022A5 (enExample) | 2014-04-03 |
| JP5902628B2 true JP5902628B2 (ja) | 2016-04-13 |
Family
ID=44063696
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012545143A Active JP5902628B2 (ja) | 2009-12-22 | 2010-12-17 | 相乗的抗ウイルス組成物及びその使用 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US10022449B2 (enExample) |
| EP (1) | EP2515889B1 (enExample) |
| JP (1) | JP5902628B2 (enExample) |
| KR (1) | KR101862415B1 (enExample) |
| CN (1) | CN102652017A (enExample) |
| AU (1) | AU2010335594B2 (enExample) |
| BR (1) | BR112012015202B1 (enExample) |
| CA (1) | CA2779532C (enExample) |
| CL (1) | CL2012001695A1 (enExample) |
| DK (1) | DK2515889T3 (enExample) |
| EA (1) | EA022840B1 (enExample) |
| ES (1) | ES2531367T3 (enExample) |
| IL (1) | IL219552A (enExample) |
| MX (1) | MX2012007166A (enExample) |
| NZ (1) | NZ599839A (enExample) |
| PL (1) | PL2515889T3 (enExample) |
| PT (1) | PT2515889E (enExample) |
| SG (1) | SG181421A1 (enExample) |
| SI (1) | SI2515889T1 (enExample) |
| WO (1) | WO2011076367A2 (enExample) |
| ZA (1) | ZA201202482B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012126777A1 (en) * | 2011-03-18 | 2012-09-27 | Marinomed Biotechnologie Gmbh | Inhibition of neuraminidase activity |
| RU2469020C1 (ru) * | 2011-11-08 | 2012-12-10 | Александр Васильевич Иващенко | (3r,4r,5s)-5-амино-4-ациламино-3-(1-этил-пропокси)-циклогекс-1-ен-карбоновые кислоты, их эфиры и способ применения |
| RU2520836C1 (ru) * | 2013-02-27 | 2014-06-27 | Александр Васильевич Иващенко | (3r,4r,5s)-4-амино-5-(2,2-дифторацетиламино)-3-(1-этилпропокси)-циклогекс-1-енкарбоновая кислота и ее эфиры, способ их получения и применения |
| HUE044329T2 (hu) * | 2014-01-22 | 2019-10-28 | Visufarma B V | Iota-karragént tartalmazó készítmény vírusos kötõhártya-gyulladás ellen |
| CN117942405A (zh) * | 2016-02-25 | 2024-04-30 | 应用生物实验室公司 | 保护空气传播的病原体和刺激物的组合物和方法 |
| US11304989B2 (en) * | 2017-10-06 | 2022-04-19 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd | Peptides for use in the treatment of viral infections |
| WO2019160261A1 (ko) * | 2018-02-14 | 2019-08-22 | (주)나노메디카 | 항바이러스 처리 방법, 항바이러스 필터, 및 이를 구비한 마스크 |
| KR102316819B1 (ko) * | 2018-04-20 | 2021-10-25 | 한미약품 주식회사 | 카라기난을 유효성분으로 포함하는 보존성이 개선된 액상 제제 |
| GB2579600B (en) | 2018-12-05 | 2023-07-05 | Byotrol Plc | Anti-viral composition |
| US12245754B2 (en) * | 2019-07-03 | 2025-03-11 | Aillis Inc. | Pharmaceutical composition for treating influenza virus infections |
| WO2021184123A1 (en) * | 2020-03-18 | 2021-09-23 | Encyt Technologies, Inc. | Compositions and methods for the treatment of coronavirus infection and respiratory compromise |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6593314B1 (en) * | 1999-10-19 | 2003-07-15 | Abbott Laboratories | Neuraminidase inhibitors |
| JP2001181188A (ja) * | 1999-12-28 | 2001-07-03 | Marine Biotechnol Inst Co Ltd | インフルエンザウイルス感染阻害剤 |
| DE602007005697D1 (de) | 2006-12-05 | 2010-05-12 | Marinomed Biotechnologie Gmbh | Verwendung von carrageenan zur behandlung von rhinovirus-infektionen |
| EP1930015A1 (en) * | 2006-12-05 | 2008-06-11 | Marinomed Biotechnologie GmbH | Use of carrageenan for treating rhinovirus infections |
| CA2673313A1 (en) * | 2006-12-18 | 2008-12-04 | Amcol International | Virus-interacting layered phyllosilicates and methods of use |
| PL2178533T3 (pl) | 2007-08-24 | 2013-08-30 | Marinomed Biotechnologie Gmbh | Kompozycja przeciwwirusowa zawierająca siarczanowany polisacharyd: jota-karagen |
-
2010
- 2010-12-17 DK DK10810910.9T patent/DK2515889T3/en active
- 2010-12-17 ES ES10810910T patent/ES2531367T3/es active Active
- 2010-12-17 MX MX2012007166A patent/MX2012007166A/es active IP Right Grant
- 2010-12-17 WO PCT/EP2010/007726 patent/WO2011076367A2/en not_active Ceased
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- 2010-12-17 NZ NZ599839A patent/NZ599839A/en unknown
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Also Published As
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|---|---|
| NZ599839A (en) | 2014-02-28 |
| KR101862415B1 (ko) | 2018-05-29 |
| SG181421A1 (en) | 2012-07-30 |
| PT2515889E (pt) | 2015-03-20 |
| AU2010335594A1 (en) | 2012-05-24 |
| ES2531367T3 (es) | 2015-03-13 |
| PL2515889T3 (pl) | 2015-05-29 |
| SI2515889T1 (sl) | 2015-04-30 |
| EA022840B1 (ru) | 2016-03-31 |
| CL2012001695A1 (es) | 2013-03-08 |
| US10022449B2 (en) | 2018-07-17 |
| DK2515889T3 (en) | 2015-03-02 |
| EA201290373A1 (ru) | 2012-11-30 |
| JP2013515022A (ja) | 2013-05-02 |
| IL219552A0 (en) | 2012-06-28 |
| CA2779532C (en) | 2018-05-22 |
| CN102652017A (zh) | 2012-08-29 |
| MX2012007166A (es) | 2012-07-23 |
| ZA201202482B (en) | 2012-12-27 |
| EP2515889A2 (en) | 2012-10-31 |
| IL219552A (en) | 2016-11-30 |
| BR112012015202B1 (pt) | 2020-12-08 |
| WO2011076367A2 (en) | 2011-06-30 |
| KR20120107970A (ko) | 2012-10-04 |
| BR112012015202A2 (pt) | 2016-04-05 |
| EP2515889B1 (en) | 2014-12-10 |
| WO2011076367A3 (en) | 2011-09-01 |
| US20120302522A1 (en) | 2012-11-29 |
| AU2010335594B2 (en) | 2015-05-21 |
| CA2779532A1 (en) | 2011-06-30 |
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