JP5860409B2 - 徐放性核酸マトリックス組成物 - Google Patents

徐放性核酸マトリックス組成物 Download PDF

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JP5860409B2
JP5860409B2 JP2012548536A JP2012548536A JP5860409B2 JP 5860409 B2 JP5860409 B2 JP 5860409B2 JP 2012548536 A JP2012548536 A JP 2012548536A JP 2012548536 A JP2012548536 A JP 2012548536A JP 5860409 B2 JP5860409 B2 JP 5860409B2
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another embodiment
matrix composition
nucleic acid
lipid
matrix
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JP2013517265A5 (OSRAM
JP2013517265A (ja
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エマヌエル,ノアム
ローゼンフェルド,ヨセフ
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ポリピッド リミテッド
ポリピッド リミテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007Drug-containing films, membranes or sheets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
JP2012548536A 2010-01-19 2011-01-18 徐放性核酸マトリックス組成物 Active JP5860409B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29604010P 2010-01-19 2010-01-19
US61/296,040 2010-01-19
PCT/IL2011/000054 WO2011089595A2 (en) 2010-01-19 2011-01-18 Sustained-release nucleic acid matrix compositions

Publications (3)

Publication Number Publication Date
JP2013517265A JP2013517265A (ja) 2013-05-16
JP2013517265A5 JP2013517265A5 (OSRAM) 2014-03-06
JP5860409B2 true JP5860409B2 (ja) 2016-02-16

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ID=44307336

Family Applications (1)

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JP2012548536A Active JP5860409B2 (ja) 2010-01-19 2011-01-18 徐放性核酸マトリックス組成物

Country Status (7)

Country Link
US (2) US8795726B2 (OSRAM)
EP (1) EP2525778B1 (OSRAM)
JP (1) JP5860409B2 (OSRAM)
CN (1) CN102892406B (OSRAM)
AU (1) AU2011208374B2 (OSRAM)
CA (1) CA2783001C (OSRAM)
WO (1) WO2011089595A2 (OSRAM)

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CN103500847B (zh) * 2013-10-02 2016-08-17 中国地质大学(武汉) 锂硫电池添加剂、含有该添加剂的正极材料及其制备方法
WO2015069870A1 (en) * 2013-11-07 2015-05-14 The University Of North Carolina At Chapel Hill Particles containing phospholipids or bioactive fatty acid
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JP2016023148A (ja) * 2014-07-17 2016-02-08 富士フイルム株式会社 脂質粒子の製造法および脂質粒子を有する核酸送達キャリア
KR20170063638A (ko) * 2014-10-02 2017-06-08 폴리피드 엘티디. 수술 부위 감염의 치료 및 예방을 위한 조성물 및 방법
AU2018341389A1 (en) * 2017-09-26 2020-04-23 Nanomi B.V. Method for preparing micro-particles by double emulsion technique
CN107823725B (zh) * 2017-10-11 2020-10-09 上海君联医疗设备有限公司 一种可延期回收的血栓滤器及其制作方法
JP6388700B2 (ja) * 2017-10-20 2018-09-12 富士フイルム株式会社 脂質粒子の製造法および脂質粒子を有する核酸送達キャリア
US11464860B2 (en) 2017-10-27 2022-10-11 Massachusetts Institute Of Technology Poly (beta-amino esters) and uses thereof
EP4379053A3 (en) 2018-10-09 2024-09-18 The University of British Columbia Compositions and systems comprising transfection-competent vesicles free of organic-solvents and detergents and methods related thereto
WO2020086965A1 (en) * 2018-10-26 2020-04-30 Massachusetts Institute Of Technology Polymer-lipids and compositions
US12433847B2 (en) 2021-03-09 2025-10-07 Massachusetts Institute Of Technology Branched poly(-amino esters) for the delivery of nucleic acids

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Also Published As

Publication number Publication date
CA2783001C (en) 2017-12-12
CN102892406B (zh) 2015-04-08
WO2011089595A3 (en) 2011-10-20
US20120294944A1 (en) 2012-11-22
CA2783001A1 (en) 2011-07-28
US20140335165A1 (en) 2014-11-13
US8795726B2 (en) 2014-08-05
EP2525778A2 (en) 2012-11-28
AU2011208374A1 (en) 2012-06-21
AU2011208374B2 (en) 2016-09-08
CN102892406A (zh) 2013-01-23
JP2013517265A (ja) 2013-05-16
EP2525778A4 (en) 2013-07-03
WO2011089595A2 (en) 2011-07-28
US9616032B2 (en) 2017-04-11
EP2525778B1 (en) 2018-08-01

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