JP5841952B2 - 腫瘍性疾患の治療的処置にて用いるための成体幹細胞由来の微細小胞（ｍｖ） - Google Patents
腫瘍性疾患の治療的処置にて用いるための成体幹細胞由来の微細小胞（ｍｖ） Download PDFInfo
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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| EP10425052A EP2363136A1 (en) | 2010-03-02 | 2010-03-02 | Microvesicles (MVs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease |
| EP10425052.7 | 2010-03-02 | ||
| PCT/EP2011/052945 WO2011107437A1 (en) | 2010-03-02 | 2011-02-28 | Microvesicles (mvs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease |
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| JP2013520971A JP2013520971A (ja) | 2013-06-10 |
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| JP5841952B2 true JP5841952B2 (ja) | 2016-01-13 |
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| EP2363136A1 (en) * | 2010-03-02 | 2011-09-07 | Fresenius Medical Care Deutschland GmbH | Microvesicles (MVs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease |
| ES2906750T3 (es) | 2010-05-12 | 2022-04-20 | Prokidney | Células renales bioactivas |
| ITRM20110403A1 (it) * | 2011-07-28 | 2013-01-29 | Ospedale Pediatrico Bambino Gesu | Microvescicole isolate da cellule mesenchimali come agenti immunosoppressori. |
| CN102357071B (zh) * | 2011-10-26 | 2013-10-23 | 重庆医科大学附属儿童医院 | 载紫杉醇纳米微泡及其制备方法 |
| PL2785359T3 (pl) * | 2011-11-30 | 2018-12-31 | Astellas Institute For Regenerative Medicine | Mezenchymalne komórki zrębowe i związane z nimi zastosowania |
| US8961956B2 (en) | 2011-11-30 | 2015-02-24 | Ocata Therapeutics, Inc. | Mesenchymal stromal cells and uses related thereto |
| US11286463B2 (en) | 2012-03-08 | 2022-03-29 | Advanced ReGen Medical Technologies, LLC | Reprogramming of aged adult stem cells |
| CN104471059B (zh) | 2012-07-12 | 2018-04-17 | 珠海横琴爱姆斯坦生物科技有限公司 | 人胚胎干细胞衍生的间充质样干细胞、方法及其应用 |
| US10772911B2 (en) | 2013-12-20 | 2020-09-15 | Advanced ReGen Medical Technologies, LLC | Cell free compositions for cellular restoration and methods of making and using same |
| US20150174166A1 (en) | 2013-12-20 | 2015-06-25 | Advanced ReGen Medical Technologies, LLC | Compositions for Cellular Restoration and Methods of Making and Using Same |
| EP3122333A4 (en) * | 2014-03-24 | 2017-11-29 | Advanced Regen Medical Technologies, LLC | Cell free compositions for cellular restoration and methods of making and using same |
| US10538738B2 (en) * | 2014-05-19 | 2020-01-21 | Eleftherios Papoutsakis | Megakaryocytic particles and microparticles for cell therapy and fate modification of stem and progenitor cells |
| CN109475645A (zh) | 2016-04-29 | 2019-03-15 | 先进瑞金医疗技术有限公司 | 微rna组合物及其制备和使用方法 |
| CA3085662A1 (en) | 2017-12-14 | 2019-06-20 | Unicyte Ev Ag | Pharmaceutical carriers containing mirnas for use in the treatment of renal cancer |
| EP3740576A4 (en) | 2018-01-18 | 2021-10-20 | Advanced Regen Medical Technologies, LLC | THERAPEUTIC COMPOSITIONS AND THEIR PREPARATION AND USE METHODS |
| WO2019197442A1 (en) * | 2018-04-12 | 2019-10-17 | Unicyte Ev Ag | A combination of active ingredients for the treatment of tumor |
| CN111494417B (zh) * | 2020-02-10 | 2024-04-09 | 寇晓星 | 诱导性细胞外囊泡在制备治疗肿瘤药物中的应用 |
| US12697307B2 (en) | 2020-05-11 | 2026-08-04 | Strm.Bio Incorporated | Compositions and methods related to megakaryocyte-derived extracellular vesicles |
| KR102601831B1 (ko) * | 2020-09-23 | 2023-11-14 | 대한민국 | 고형암 증식 억제 효과를 갖는 개과동물의 엑소좀 |
| WO2022087505A1 (en) | 2020-10-23 | 2022-04-28 | Strm.Bio Incorporated | Compositions and methods related to megakaryocyte-derived extracellular vesicles for treating myeloproliferative neoplasms |
| AU2022264498A1 (en) | 2021-04-26 | 2023-09-28 | Strm.Bio Incorporated | Compositions and methods related to megakaryocyte-derived extracellular vesicles for fanconi anemia |
| EP4534649A1 (en) * | 2023-10-03 | 2025-04-09 | Unicyte AG | A method of qualifying as pharmaceutically active a batch of undifferentiated adult stem cells having the potential to differentiate along the hepatic lineage |
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| US6088613A (en) * | 1989-12-22 | 2000-07-11 | Imarx Pharmaceutical Corp. | Method of magnetic resonance focused surgical and therapeutic ultrasound |
| AU5871898A (en) * | 1997-01-30 | 1998-08-25 | Andaris Limited | Microparticles and their use in cancer treatment |
| AU753196B2 (en) * | 1998-02-09 | 2002-10-10 | Bracco Research S.A. | Targeted delivery of biologically active media |
| US20020177551A1 (en) * | 2000-05-31 | 2002-11-28 | Terman David S. | Compositions and methods for treatment of neoplastic disease |
| US7128903B2 (en) * | 2001-10-03 | 2006-10-31 | Innovative Pharmaceutical Concepts (Ipc) Inc. | Pharmaceutical preparations useful for treating tumors and lesions of the skin and the mucous membranes and methods and kits using same |
| WO2005121369A2 (en) * | 2004-06-02 | 2005-12-22 | Sourcepharm, Inc. | Rna-containing microvesicles and methods therefor |
| US8148335B2 (en) * | 2004-06-23 | 2012-04-03 | Children's Hospital & Research Center Oakland | De-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy |
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| WO2006126219A1 (en) | 2005-05-26 | 2006-11-30 | Fresenius Medical Care Deutschland G.M.B.H. | Liver progenitor cells |
| US20090000641A1 (en) | 2007-06-28 | 2009-01-01 | Applied Materials, Inc. | Methods and apparatus for cleaning deposition chamber parts using selective spray etch |
| BRPI0816852A2 (pt) * | 2007-09-14 | 2017-06-06 | Univ Ohio State Res Found | método de diagnosticar ou prognosticar doença ou desordem em sujeito, biomarcador, método para determinar e/ou prever se sujeito tem diferenciação da desordem, biomarcador para desordem pulmonar, método para diagnosticar se sujeito tem, ou está em risco de desenvolver doença ou desordem, método de inibir a proliferação de doença ou desordem e método para identificar agente terapêutico do câncer. |
| JP5719171B2 (ja) * | 2007-10-15 | 2015-05-13 | フレゼニウス メディカル ケア ドイッチェランド ゲゼルシャフト ミット ベシュレンクテル ハフツング | 内皮細胞移植、特に膵島移植による糖尿病の処置におけるアジュバント活性を有する医薬を調製するための微小胞（ｍｖ）の使用、および関連方法 |
| CN101854941B (zh) * | 2007-10-29 | 2013-03-27 | 弗雷森纽斯医疗护理德国有限责任公司 | 衍生自干细胞的微泡(MVs)用于制备用于受损或损伤组织或器官的内皮/上皮再生的药物的用途、以及相关体外和体内方法 |
| NZ586497A (en) * | 2008-01-04 | 2012-07-27 | Lydac Neuroscience Ltd | Microvesicles |
| PT2254586E (pt) * | 2008-02-22 | 2015-05-18 | Agency Science Tech & Res | Partículas de células estaminais mesenquimais |
| EP2186883A1 (en) | 2008-11-04 | 2010-05-19 | Fresenius Medical Care | An isolated multipotent mesenchymal stem cell from human adult glomeruli (hGL-MSC), a method of preparing thereof and uses thereof in the regenerative medicine of the kidney |
| EP2363136A1 (en) * | 2010-03-02 | 2011-09-07 | Fresenius Medical Care Deutschland GmbH | Microvesicles (MVs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease |
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2010
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2011
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- 2011-02-28 WO PCT/EP2011/052945 patent/WO2011107437A1/en not_active Ceased
- 2011-02-28 PT PT117055855T patent/PT2542250E/pt unknown
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- 2011-02-28 PL PL11705585T patent/PL2542250T3/pl unknown
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2017
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2018
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| Publication number | Publication date |
|---|---|
| WO2011107437A1 (en) | 2011-09-09 |
| DK2542250T3 (en) | 2015-12-07 |
| EP2542250B1 (en) | 2015-08-26 |
| EP2542250A1 (en) | 2013-01-09 |
| CN102781454B (zh) | 2015-12-16 |
| PT2542250E (pt) | 2015-12-09 |
| US20230248774A1 (en) | 2023-08-10 |
| HUE026292T2 (en) | 2016-05-30 |
| CN102781454A (zh) | 2012-11-14 |
| JP2013520971A (ja) | 2013-06-10 |
| US10105395B2 (en) | 2018-10-23 |
| US9717760B2 (en) | 2017-08-01 |
| EP2363136A1 (en) | 2011-09-07 |
| US20120321723A1 (en) | 2012-12-20 |
| US20170348356A1 (en) | 2017-12-07 |
| PL2542250T3 (pl) | 2016-04-29 |
| ES2554492T3 (es) | 2015-12-21 |
| US20190060369A1 (en) | 2019-02-28 |
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