JP5819835B2 - 中空糸型バイオリアクタの組立方法 - Google Patents

中空糸型バイオリアクタの組立方法 Download PDF

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Publication number
JP5819835B2
JP5819835B2 JP2012533706A JP2012533706A JP5819835B2 JP 5819835 B2 JP5819835 B2 JP 5819835B2 JP 2012533706 A JP2012533706 A JP 2012533706A JP 2012533706 A JP2012533706 A JP 2012533706A JP 5819835 B2 JP5819835 B2 JP 5819835B2
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JP
Japan
Prior art keywords
cell growth
growth module
assembling
membrane
module according
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Expired - Fee Related
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JP2012533706A
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English (en)
Japanese (ja)
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JP2013507143A (ja
JP2013507143A5 (enExample
Inventor
ダルボルグ、フレドリク
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Terumo BCT Inc
Original Assignee
Terumo BCT Inc
Gambro BCT Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/10—Hollow fibers or tubes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02—Hollow fibre modules
    • B01D63/021—Manufacturing thereof
    • B01D63/0233—Manufacturing thereof forming the bundle
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02—Hollow fibre modules
    • B01D63/031—Two or more types of hollow fibres within one bundle or within one potting or tube-sheet
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0081—After-treatment of organic or inorganic membranes
    • B01D67/009—After-treatment of organic or inorganic membranes with wave-energy, particle-radiation or plasma
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
    • B01D71/06—Organic material
    • B01D71/44—Polymers obtained by reactions only involving carbon-to-carbon unsaturated bonds, not provided for in a single one of groups B01D71/26-B01D71/42
    • B01D71/441—Polyvinylpyrrolidone
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
    • B01D71/06—Organic material
    • B01D71/66—Polymers having sulfur in the main chain, with or without nitrogen, oxygen or carbon only
    • B01D71/68—Polysulfones; Polyethersulfones
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2313/00—Details relating to membrane modules or apparatus
    • B01D2313/04—Specific sealing means

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Manufacturing & Machinery (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Immunology (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Plasma & Fusion (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • External Artificial Organs (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
JP2012533706A 2009-10-12 2010-10-04 中空糸型バイオリアクタの組立方法 Expired - Fee Related JP5819835B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25075809P 2009-10-12 2009-10-12
US61/250,758 2009-10-12
PCT/IB2010/002517 WO2011045644A1 (en) 2009-10-12 2010-10-04 Method of assembling a hollow fiber bioreactor

Publications (3)

Publication Number Publication Date
JP2013507143A JP2013507143A (ja) 2013-03-04
JP2013507143A5 JP2013507143A5 (enExample) 2013-11-21
JP5819835B2 true JP5819835B2 (ja) 2015-11-24

Family

ID=43640470

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012533706A Expired - Fee Related JP5819835B2 (ja) 2009-10-12 2010-10-04 中空糸型バイオリアクタの組立方法

Country Status (5)

Country Link
US (1) US20120205041A1 (enExample)
EP (1) EP2488629B1 (enExample)
JP (1) JP5819835B2 (enExample)
CN (1) CN102639688B (enExample)
WO (1) WO2011045644A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2013142684A (ru) 2011-02-22 2015-03-27 Реджентс Оф Юниверсити Оф Миннесота (Сша) Инкапсулированные в диоксиде кремния биоматериалы
US9534236B2 (en) * 2013-03-08 2017-01-03 Regents Of The University Of Minnesota Membranes for wastewater-generated energy and gas
US10035719B2 (en) 2014-10-15 2018-07-31 Regents Of The University Of Minnesota System and membrane for wastewater-generated energy and gas
EP3830236A2 (en) 2018-08-16 2021-06-09 TERUMO Kabushiki Kaisha Cell culture substrate
EP3830237A1 (en) 2018-08-16 2021-06-09 TERUMO Kabushiki Kaisha Cell culture substrate
EP3830239A1 (en) 2018-08-16 2021-06-09 TERUMO Kabushiki Kaisha Cell culture substrate
JP7319349B2 (ja) 2018-08-16 2023-08-01 テルモ株式会社 細胞培養基材
WO2020130032A1 (en) 2018-12-20 2020-06-25 Terumo Kabushiki Kaisha Cell culture substrate
US12404485B2 (en) 2018-12-20 2025-09-02 Terumo Kabushiki Kaisha Cell culture substrate
JP7595066B2 (ja) 2019-09-20 2024-12-05 テルモ株式会社 タンパク質吸着剤の被覆状態またはタンパク質の吸着状態の評価方法
JP2023072702A (ja) 2020-06-18 2023-05-25 テルモ株式会社 細胞培養基材
KR20230042266A (ko) * 2020-07-29 2023-03-28 엘지전자 주식회사 나노셀룰로오스 지지체 및 그의 제조 방법
WO2023120710A1 (ja) * 2021-12-23 2023-06-29 国立大学法人東京大学 人工三次元組織製造方法、人工三次元組織製造装置、および人工三次元組織体

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63196286A (ja) * 1987-02-12 1988-08-15 Sumitomo Electric Ind Ltd 細胞培養用基材
JPS63198980A (ja) * 1987-02-13 1988-08-17 Sumitomo Electric Ind Ltd 細胞培養用基材
US5015585A (en) * 1988-02-23 1991-05-14 Robinson James R Method and apparatus for culturing and diffusively oxygenating cells on isotropic membranes
JPH0315382A (ja) * 1989-06-14 1991-01-23 Terumo Corp 細胞培養用基材、細胞培養用基材ユニット、バイオリアクターおよび体外循環式治療器
US5369012A (en) * 1992-03-26 1994-11-29 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Method of making a membrane having hydrophilic and hydrophobic surfaces for adhering cells or antibodies by using atomic oxygen or hydroxyl radicals
JPH05308953A (ja) * 1992-05-13 1993-11-22 Asahi Medical Co Ltd 細胞培養膜
DE19932439C2 (de) * 1999-07-12 2002-06-13 Sefar Ag Rueschlikon Bioreaktor
JP2002065246A (ja) * 2000-06-15 2002-03-05 Sumitomo Bakelite Co Ltd 細胞培養基質、その製造方法及び細胞培養方法
US6617152B2 (en) * 2001-09-04 2003-09-09 Corning Inc Method for creating a cell growth surface on a polymeric substrate
JP4453248B2 (ja) * 2001-12-19 2010-04-21 東レ株式会社 中空糸膜および中空糸膜モジュールの製造方法
US20050273031A1 (en) * 2002-08-21 2005-12-08 Tory Industries, Inc. Modified substrate and process for producing modified substrate
JP2004208692A (ja) * 2002-12-17 2004-07-29 Toray Ind Inc 三次元細胞培養基材および細胞製剤の製造方法
JP2004305840A (ja) * 2003-04-03 2004-11-04 Toyobo Co Ltd 中空糸膜の保存方法
US7837042B2 (en) * 2004-08-10 2010-11-23 Nipro Corporation Polysulfone type selectively permeable hollow fiber membrane module and process for manufacturing the same
CA2783759C (en) * 2005-03-24 2015-12-15 Xyleco, Inc. Fibrous materials and composites
US20080299337A1 (en) * 2006-02-09 2008-12-04 Isoflux, Inc. Method for the formation of surfaces on the inside of medical devices
US20100227372A1 (en) * 2007-07-27 2010-09-09 The University Of Sydney Biological functionalisation of substrates
EP2168666A1 (en) * 2008-09-25 2010-03-31 Gambro Lundia AB Irradiated membrane for cell expansion
EP2314672B1 (en) * 2008-09-25 2015-04-15 Gambro Lundia AB Hybrid bioartificial kidney
CN101549179B (zh) * 2009-04-30 2011-09-14 浙江大学 人工肝用多孔砖式填充支架型反应器

Also Published As

Publication number Publication date
EP2488629B1 (en) 2020-03-11
US20120205041A1 (en) 2012-08-16
WO2011045644A1 (en) 2011-04-21
CN102639688B (zh) 2014-12-31
JP2013507143A (ja) 2013-03-04
EP2488629A1 (en) 2012-08-22
CN102639688A (zh) 2012-08-15

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