JP5815746B2 - Ｃ型肝炎ウイルス阻害剤 - Google Patents

Ｃ型肝炎ウイルス阻害剤 Download PDF

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Publication number
JP5815746B2
JP5815746B2 JP2013552620A JP2013552620A JP5815746B2 JP 5815746 B2 JP5815746 B2 JP 5815746B2 JP 2013552620 A JP2013552620 A JP 2013552620A JP 2013552620 A JP2013552620 A JP 2013552620A JP 5815746 B2 JP5815746 B2 JP 5815746B2
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JP
Japan
Prior art keywords
hcv
mmol
pharmaceutically acceptable
interferon
acceptable salt
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Expired - Fee Related
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JP2013552620A
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English (en)
Japanese (ja)
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JP2014504643A5 (enExample
JP2014504643A (ja
Inventor
ジョン・エイ・ベンダー
オマール・ディ・ロペス
ガン・ワン
マコネン・ベレマ
ジョン・エフ・カドウ
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Bristol Myers Squibb Co
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Bristol Myers Squibb Co
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Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
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Publication of JP2014504643A5 publication Critical patent/JP2014504643A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/04—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D309/06—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
JP2013552620A 2011-02-07 2012-02-02 Ｃ型肝炎ウイルス阻害剤 Expired - Fee Related JP5815746B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161440086P 2011-02-07 2011-02-07
US61/440,086 2011-02-07
US201161467602P 2011-03-25 2011-03-25
US61/467,602 2011-03-25
PCT/US2012/023595 WO2012109080A1 (en) 2011-02-07 2012-02-02 Hepatitis c virus inhibitors

Publications (3)

Publication Number Publication Date
JP2014504643A JP2014504643A (ja) 2014-02-24
JP2014504643A5 JP2014504643A5 (enExample) 2015-03-05
JP5815746B2 true JP5815746B2 (ja) 2015-11-17

Family

ID=45688244

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013552620A Expired - Fee Related JP5815746B2 (ja) 2011-02-07 2012-02-02 Ｃ型肝炎ウイルス阻害剤

Country Status (23)

Country Link
US (2) US8552047B2 (enExample)
EP (1) EP2673271B1 (enExample)
JP (1) JP5815746B2 (enExample)
KR (1) KR20140048848A (enExample)
CN (1) CN103347878B (enExample)
AR (1) AR085327A1 (enExample)
AU (1) AU2012214767B2 (enExample)
BR (1) BR112013020042A2 (enExample)
CA (1) CA2826774A1 (enExample)
CL (1) CL2013002241A1 (enExample)
CO (1) CO6761335A2 (enExample)
EA (1) EA021538B1 (enExample)
ES (1) ES2540052T3 (enExample)
IL (1) IL227789A0 (enExample)
MA (1) MA34896B1 (enExample)
MX (1) MX2013008419A (enExample)
PE (1) PE20140302A1 (enExample)
PH (1) PH12013501543A1 (enExample)
SG (1) SG192267A1 (enExample)
TW (1) TWI542585B (enExample)
UY (1) UY33897A (enExample)
WO (1) WO2012109080A1 (enExample)
ZA (1) ZA201306720B (enExample)

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AR085327A1 (es) 2013-09-25
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CO6761335A2 (es) 2013-09-30
EA021538B1 (ru) 2015-07-30
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CL2013002241A1 (es) 2013-12-13
PH12013501543A1 (en) 2013-09-23
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KR20140048848A (ko) 2014-04-24
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UY33897A (es) 2012-08-31
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