JP5813778B2 - トール様受容体に基づく免疫反応を調節するための免疫調節オリゴヌクレオチド（ｉｒｏ）化合物 - Google Patents

トール様受容体に基づく免疫反応を調節するための免疫調節オリゴヌクレオチド（ｉｒｏ）化合物 Download PDF

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JP5813778B2
JP5813778B2 JP2013540054A JP2013540054A JP5813778B2 JP 5813778 B2 JP5813778 B2 JP 5813778B2 JP 2013540054 A JP2013540054 A JP 2013540054A JP 2013540054 A JP2013540054 A JP 2013540054A JP 5813778 B2 JP5813778 B2 JP 5813778B2
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JP2013544816A5 (enExample
JP2013544816A (ja
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エカンバー・アール・カンディマラ
ダチン・ワン
イレネウシュ・ノヴァク
スディール・アグラワル
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Aceragen Inc
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Idera Pharmaceuticals Inc
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JP2013540054A 2010-11-19 2011-11-18 トール様受容体に基づく免疫反応を調節するための免疫調節オリゴヌクレオチド（ｉｒｏ）化合物 Expired - Fee Related JP5813778B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US41549410P 2010-11-19 2010-11-19
US61/415,494 2010-11-19
US201161511709P 2011-07-26 2011-07-26
US61/511,709 2011-07-26
PCT/US2011/061412 WO2012068470A2 (en) 2010-11-19 2011-11-18 Immune regulatory oligonucleotide (iro) compounds to modulate toll-like receptor based immune response

Publications (3)

Publication Number Publication Date
JP2013544816A JP2013544816A (ja) 2013-12-19
JP2013544816A5 JP2013544816A5 (enExample) 2015-02-26
JP5813778B2 true JP5813778B2 (ja) 2015-11-17

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JP2013540054A Expired - Fee Related JP5813778B2 (ja) 2010-11-19 2011-11-18 トール様受容体に基づく免疫反応を調節するための免疫調節オリゴヌクレオチド（ｉｒｏ）化合物

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US (5) US8486908B2 (enExample)
EP (2) EP2640420B1 (enExample)
JP (1) JP5813778B2 (enExample)
KR (2) KR101985382B1 (enExample)
CN (2) CN107012149A (enExample)
AU (4) AU2011329668B2 (enExample)
CA (1) CA2817891C (enExample)
ES (1) ES2697606T3 (enExample)
MX (1) MX340363B (enExample)
WO (1) WO2012068470A2 (enExample)

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JP4874801B2 (ja) * 2003-06-11 2012-02-15 イデラ ファーマシューティカルズ インコーポレイテッド 安定化免疫調節オリゴヌクレオチド
EP2525780B1 (en) 2010-01-19 2022-09-07 Northwestern University Synthetic nanostructures including nucleic acids and/or other entities
CA2807552A1 (en) 2010-08-06 2012-02-09 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
EP2857499A1 (en) 2010-10-01 2015-04-08 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
CN107012149A (zh) * 2010-11-19 2017-08-04 艾德拉药物股份有限公司 调控基于toll‑样受体的免疫应答的免疫调节寡核苷酸(iro)化合物
CA2831613A1 (en) 2011-03-31 2012-10-04 Moderna Therapeutics, Inc. Delivery and formulation of engineered nucleic acids
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
PT3682905T (pt) 2011-10-03 2022-04-07 Modernatx Inc Nucleósidos, nucleótidos e ácidos nucleicos modificados e respetivas utilizações
ES2923757T3 (es) 2011-12-16 2022-09-30 Modernatx Inc Composiciones de ARNm modificado
WO2013151664A1 (en) 2012-04-02 2013-10-10 modeRNA Therapeutics Modified polynucleotides for the production of proteins
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
US10501512B2 (en) 2012-04-02 2019-12-10 Modernatx, Inc. Modified polynucleotides
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
PT2922554T (pt) 2012-11-26 2022-06-28 Modernatx Inc Arn modificado nas porções terminais
CN103880941B (zh) * 2012-12-21 2016-02-10 苏州偲聚生物材料有限公司 多肽、包含该多肽的检测器件和检测试剂盒
AU2014205544B2 (en) * 2013-01-08 2018-07-12 Idera Pharmaceuticals, Inc. Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
EP2754714A1 (en) * 2013-01-14 2014-07-16 Sarepta Therapeutics, Inc. Inhibitory oligonucleotides and their use in therapy
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
CN104098671A (zh) * 2013-04-03 2014-10-15 苏州偲聚生物材料有限公司 多肽、包含该多肽的检测器件和检测试剂盒
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