AU2011329668B2 - Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response - Google Patents

Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Download PDF

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Publication number
AU2011329668B2
AU2011329668B2 AU2011329668A AU2011329668A AU2011329668B2 AU 2011329668 B2 AU2011329668 B2 AU 2011329668B2 AU 2011329668 A AU2011329668 A AU 2011329668A AU 2011329668 A AU2011329668 A AU 2011329668A AU 2011329668 B2 AU2011329668 B2 AU 2011329668B2
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Prior art keywords
disease
syndrome
tlr7
tlr9
autoimmune
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AU2011329668A2 (en
AU2011329668A1 (en
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Sudhir Agrawal
Ekambar R. Kandimalla
Ireneusz Nowak
Daqing Wang
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Aceragen Inc
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Idera Pharmaceuticals Inc
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Priority to AU2016250372A priority Critical patent/AU2016250372B2/en
Priority to AU2018204878A priority patent/AU2018204878A1/en
Priority to AU2020202827A priority patent/AU2020202827B2/en
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    • C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
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    • A61K31/7115—Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
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AU2011329668A 2010-11-19 2011-11-18 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Ceased AU2011329668B2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2016250372A AU2016250372B2 (en) 2010-11-19 2016-10-26 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
AU2018204878A AU2018204878A1 (en) 2010-11-19 2018-07-04 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
AU2020202827A AU2020202827B2 (en) 2010-11-19 2020-04-29 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US41549410P 2010-11-19 2010-11-19
US61/415,494 2010-11-19
US201161511709P 2011-07-26 2011-07-26
US61/511,709 2011-07-26
PCT/US2011/061412 WO2012068470A2 (en) 2010-11-19 2011-11-18 Immune regulatory oligonucleotide (iro) compounds to modulate toll-like receptor based immune response

Related Child Applications (1)

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AU2016250372A Division AU2016250372B2 (en) 2010-11-19 2016-10-26 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response

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AU2011329668A1 AU2011329668A1 (en) 2013-06-13
AU2011329668A2 AU2011329668A2 (en) 2013-06-27
AU2011329668B2 true AU2011329668B2 (en) 2016-07-28

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Application Number Title Priority Date Filing Date
AU2011329668A Ceased AU2011329668B2 (en) 2010-11-19 2011-11-18 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
AU2016250372A Ceased AU2016250372B2 (en) 2010-11-19 2016-10-26 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
AU2018204878A Abandoned AU2018204878A1 (en) 2010-11-19 2018-07-04 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
AU2020202827A Ceased AU2020202827B2 (en) 2010-11-19 2020-04-29 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response

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AU2016250372A Ceased AU2016250372B2 (en) 2010-11-19 2016-10-26 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
AU2018204878A Abandoned AU2018204878A1 (en) 2010-11-19 2018-07-04 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
AU2020202827A Ceased AU2020202827B2 (en) 2010-11-19 2020-04-29 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response

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US (5) US8486908B2 (enExample)
EP (2) EP2640420B1 (enExample)
JP (1) JP5813778B2 (enExample)
KR (2) KR101985382B1 (enExample)
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AU (4) AU2011329668B2 (enExample)
CA (1) CA2817891C (enExample)
ES (1) ES2697606T3 (enExample)
MX (1) MX340363B (enExample)
WO (1) WO2012068470A2 (enExample)

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MXPA05013658A (es) * 2003-06-11 2006-03-02 Hybridon Inc Oligonucleotidos inmunomoduladores estabilizados.
JP5863670B2 (ja) 2010-01-19 2016-02-17 ノースウェスタン ユニバーシティ 核酸および／または他の構成要素を含有している合成ナノ構造体
CA2807552A1 (en) 2010-08-06 2012-02-09 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
ES3005233T3 (en) 2010-10-01 2025-03-14 Modernatx Inc Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
JP5813778B2 (ja) * 2010-11-19 2015-11-17 イデラ ファーマシューティカルズ インコーポレイテッドＩｄｅｒａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． トール様受容体に基づく免疫反応を調節するための免疫調節オリゴヌクレオチド（ｉｒｏ）化合物
JP2014511687A (ja) 2011-03-31 2014-05-19 モデルナ セラピューティクス インコーポレイテッド 工学操作された核酸の送達および製剤
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
EP2763701B1 (en) 2011-10-03 2018-12-19 Moderna Therapeutics, Inc. Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
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