AU2011329668B2 - Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response - Google Patents
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response Download PDFInfo
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- AU2011329668B2 AU2011329668B2 AU2011329668A AU2011329668A AU2011329668B2 AU 2011329668 B2 AU2011329668 B2 AU 2011329668B2 AU 2011329668 A AU2011329668 A AU 2011329668A AU 2011329668 A AU2011329668 A AU 2011329668A AU 2011329668 B2 AU2011329668 B2 AU 2011329668B2
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- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
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- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7115—Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
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- A61K31/7125—Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters
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Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2016250372A AU2016250372B2 (en) | 2010-11-19 | 2016-10-26 | Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response |
| AU2018204878A AU2018204878A1 (en) | 2010-11-19 | 2018-07-04 | Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response |
| AU2020202827A AU2020202827B2 (en) | 2010-11-19 | 2020-04-29 | Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41549410P | 2010-11-19 | 2010-11-19 | |
| US61/415,494 | 2010-11-19 | ||
| US201161511709P | 2011-07-26 | 2011-07-26 | |
| US61/511,709 | 2011-07-26 | ||
| PCT/US2011/061412 WO2012068470A2 (en) | 2010-11-19 | 2011-11-18 | Immune regulatory oligonucleotide (iro) compounds to modulate toll-like receptor based immune response |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2016250372A Division AU2016250372B2 (en) | 2010-11-19 | 2016-10-26 | Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| AU2011329668A1 AU2011329668A1 (en) | 2013-06-13 |
| AU2011329668A2 AU2011329668A2 (en) | 2013-06-27 |
| AU2011329668B2 true AU2011329668B2 (en) | 2016-07-28 |
Family
ID=46064566
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2011329668A Ceased AU2011329668B2 (en) | 2010-11-19 | 2011-11-18 | Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response |
| AU2016250372A Ceased AU2016250372B2 (en) | 2010-11-19 | 2016-10-26 | Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response |
| AU2018204878A Abandoned AU2018204878A1 (en) | 2010-11-19 | 2018-07-04 | Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response |
| AU2020202827A Ceased AU2020202827B2 (en) | 2010-11-19 | 2020-04-29 | Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2016250372A Ceased AU2016250372B2 (en) | 2010-11-19 | 2016-10-26 | Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response |
| AU2018204878A Abandoned AU2018204878A1 (en) | 2010-11-19 | 2018-07-04 | Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response |
| AU2020202827A Ceased AU2020202827B2 (en) | 2010-11-19 | 2020-04-29 | Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US8486908B2 (enExample) |
| EP (2) | EP2640420B1 (enExample) |
| JP (1) | JP5813778B2 (enExample) |
| KR (2) | KR101985382B1 (enExample) |
| CN (2) | CN107012149A (enExample) |
| AU (4) | AU2011329668B2 (enExample) |
| CA (1) | CA2817891C (enExample) |
| ES (1) | ES2697606T3 (enExample) |
| MX (1) | MX340363B (enExample) |
| WO (1) | WO2012068470A2 (enExample) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4874801B2 (ja) * | 2003-06-11 | 2012-02-15 | イデラ ファーマシューティカルズ インコーポレイテッド | 安定化免疫調節オリゴヌクレオチド |
| EP2525780B1 (en) | 2010-01-19 | 2022-09-07 | Northwestern University | Synthetic nanostructures including nucleic acids and/or other entities |
| CA2807552A1 (en) | 2010-08-06 | 2012-02-09 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| EP2857499A1 (en) | 2010-10-01 | 2015-04-08 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| CN107012149A (zh) * | 2010-11-19 | 2017-08-04 | 艾德拉药物股份有限公司 | 调控基于toll‑样受体的免疫应答的免疫调节寡核苷酸(iro)化合物 |
| CA2831613A1 (en) | 2011-03-31 | 2012-10-04 | Moderna Therapeutics, Inc. | Delivery and formulation of engineered nucleic acids |
| US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| PT3682905T (pt) | 2011-10-03 | 2022-04-07 | Modernatx Inc | Nucleósidos, nucleótidos e ácidos nucleicos modificados e respetivas utilizações |
| ES2923757T3 (es) | 2011-12-16 | 2022-09-30 | Modernatx Inc | Composiciones de ARNm modificado |
| WO2013151664A1 (en) | 2012-04-02 | 2013-10-10 | modeRNA Therapeutics | Modified polynucleotides for the production of proteins |
| US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
| US10501512B2 (en) | 2012-04-02 | 2019-12-10 | Modernatx, Inc. | Modified polynucleotides |
| US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
| PT2922554T (pt) | 2012-11-26 | 2022-06-28 | Modernatx Inc | Arn modificado nas porções terminais |
| CN103880941B (zh) * | 2012-12-21 | 2016-02-10 | 苏州偲聚生物材料有限公司 | 多肽、包含该多肽的检测器件和检测试剂盒 |
| AU2014205544B2 (en) * | 2013-01-08 | 2018-07-12 | Idera Pharmaceuticals, Inc. | Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response |
| EP2754714A1 (en) * | 2013-01-14 | 2014-07-16 | Sarepta Therapeutics, Inc. | Inhibitory oligonucleotides and their use in therapy |
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| CN104098671A (zh) * | 2013-04-03 | 2014-10-15 | 苏州偲聚生物材料有限公司 | 多肽、包含该多肽的检测器件和检测试剂盒 |
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