JP5791895B2 - 遺伝子操作されたウサギ抗体可変ドメイン及びその使用 - Google Patents

遺伝子操作されたウサギ抗体可変ドメイン及びその使用 Download PDF

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JP5791895B2
JP5791895B2 JP2010506111A JP2010506111A JP5791895B2 JP 5791895 B2 JP5791895 B2 JP 5791895B2 JP 2010506111 A JP2010506111 A JP 2010506111A JP 2010506111 A JP2010506111 A JP 2010506111A JP 5791895 B2 JP5791895 B2 JP 5791895B2
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rabbit
antigen
amino acid
immunospecific
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JP2010525808A (ja
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ゴンカルベス ジョアン マヌエル ブラス
ゴンカルベス ジョアン マヌエル ブラス
アイレス ダ シルバ フレデリコ ヌノ カスタニェイラ
アイレス ダ シルバ フレデリコ ヌノ カスタニェイラ
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テクノファージ， インベスティガサン エ デセンボルビメント エム ビオテクノロジア，エスエー
テクノファージ， インベスティガサン エ デセンボルビメント エム ビオテクノロジア，エスエー
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567—Framework region [FR]

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2010506111A 2007-05-04 2008-04-30 遺伝子操作されたウサギ抗体可変ドメイン及びその使用 Active JP5791895B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US91622607P 2007-05-04 2007-05-04
US60/916,226 2007-05-04
PCT/PT2008/000018 WO2008136694A1 (en) 2007-05-04 2008-04-30 Engineered rabbit antibody variable domains and uses thereof

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2014185553A Division JP2015012869A (ja) 2007-05-04 2014-09-11 遺伝子操作されたウサギ抗体可変ドメイン及びその使用
JP2015094546A Division JP2015164940A (ja) 2007-05-04 2015-05-07 遺伝子操作されたウサギ抗体可変ドメイン及びその使用

Publications (2)

Publication Number Publication Date
JP2010525808A JP2010525808A (ja) 2010-07-29
JP5791895B2 true JP5791895B2 (ja) 2015-10-07

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ID=39735911

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2010506111A Active JP5791895B2 (ja) 2007-05-04 2008-04-30 遺伝子操作されたウサギ抗体可変ドメイン及びその使用
JP2014185553A Pending JP2015012869A (ja) 2007-05-04 2014-09-11 遺伝子操作されたウサギ抗体可変ドメイン及びその使用
JP2015094546A Ceased JP2015164940A (ja) 2007-05-04 2015-05-07 遺伝子操作されたウサギ抗体可変ドメイン及びその使用

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2014185553A Pending JP2015012869A (ja) 2007-05-04 2014-09-11 遺伝子操作されたウサギ抗体可変ドメイン及びその使用
JP2015094546A Ceased JP2015164940A (ja) 2007-05-04 2015-05-07 遺伝子操作されたウサギ抗体可変ドメイン及びその使用

Country Status (9)

Country Link
US (2) US10280211B2 (enExample)
EP (1) EP2164868B1 (enExample)
JP (3) JP5791895B2 (enExample)
AU (1) AU2008246442B2 (enExample)
CA (1) CA2685213C (enExample)
ES (1) ES2540807T3 (enExample)
PT (1) PT2164868E (enExample)
SG (1) SG194368A1 (enExample)
WO (1) WO2008136694A1 (enExample)

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US11685773B2 (en) 2015-04-30 2023-06-27 Abcheck S.R.O. Method for mass humanization of rabbit antibodies
EP3795591B1 (en) * 2015-06-19 2023-09-27 Eisai R&D Management Co., Ltd. Cys80 conjugated immunoglobulins
WO2019233984A1 (en) * 2018-06-08 2019-12-12 Ventana Medical Systems, Inc. Universal or normalized antibody frameworks for improved functionality and manufacturability
WO2023039612A1 (en) * 2021-09-13 2023-03-16 The Board Of Regents Of The University Of Texas System Trem2 antigen binding proteins and uses thereof

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Also Published As

Publication number Publication date
ES2540807T3 (es) 2015-07-13
JP2015164940A (ja) 2015-09-17
SG194368A1 (en) 2013-11-29
CA2685213A1 (en) 2008-11-13
AU2008246442B2 (en) 2014-07-03
PT2164868E (pt) 2015-08-04
JP2015012869A (ja) 2015-01-22
US20190256578A1 (en) 2019-08-22
WO2008136694A1 (en) 2008-11-13
JP2010525808A (ja) 2010-07-29
EP2164868A1 (en) 2010-03-24
WO2008136694A9 (en) 2010-09-02
EP2164868B1 (en) 2015-03-25
CA2685213C (en) 2017-02-21
AU2008246442A1 (en) 2008-11-13
US10280211B2 (en) 2019-05-07
US20100136627A1 (en) 2010-06-03

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