|
US598520A
(en)
|
|
1898-02-08 |
|
Marker s record for laundrymen |
|
US4741900A
(en)
|
1982-11-16 |
1988-05-03 |
Cytogen Corporation |
Antibody-metal ion complexes
|
|
GB8308235D0
(en)
|
1983-03-25 |
1983-05-05 |
Celltech Ltd |
Polypeptides
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
GB8314362D0
(en)
|
1983-05-24 |
1983-06-29 |
Celltech Ltd |
Polypeptide and protein products
|
|
US4544545A
(en)
|
1983-06-20 |
1985-10-01 |
Trustees University Of Massachusetts |
Liposomes containing modified cholesterol for organ targeting
|
|
US5807715A
(en)
|
1984-08-27 |
1998-09-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
|
|
US4676980A
(en)
|
1985-09-23 |
1987-06-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Target specific cross-linked heteroantibodies
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
GB8607679D0
(en)
|
1986-03-27 |
1986-04-30 |
Winter G P |
Recombinant dna product
|
|
AU600575B2
(en)
|
1987-03-18 |
1990-08-16 |
Sb2, Inc. |
Altered antibodies
|
|
US4880078A
(en)
|
1987-06-29 |
1989-11-14 |
Honda Giken Kogyo Kabushiki Kaisha |
Exhaust muffler
|
|
US5336603A
(en)
|
1987-10-02 |
1994-08-09 |
Genentech, Inc. |
CD4 adheson variants
|
|
EP1997891A1
(en)
|
1988-09-02 |
2008-12-03 |
Dyax Corporation |
Generation and selection of recombinant varied binding proteins
|
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
KR900005995A
(ko)
|
1988-10-31 |
1990-05-07 |
우메모또 요시마사 |
변형 인터류킨-2 및 그의 제조방법
|
|
US20040049014A1
(en)
|
1988-12-28 |
2004-03-11 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5112946A
(en)
|
1989-07-06 |
1992-05-12 |
Repligen Corporation |
Modified pf4 compositions and methods of use
|
|
US5013556A
(en)
|
1989-10-20 |
1991-05-07 |
Liposome Technology, Inc. |
Liposomes with enhanced circulation time
|
|
WO1991006570A1
(en)
|
1989-10-25 |
1991-05-16 |
The University Of Melbourne |
HYBRID Fc RECEPTOR MOLECULES
|
|
GB8928874D0
(en)
|
1989-12-21 |
1990-02-28 |
Celltech Ltd |
Humanised antibodies
|
|
WO1991010737A1
(en)
|
1990-01-11 |
1991-07-25 |
Molecular Affinities Corporation |
Production of antibodies using gene libraries
|
|
US5780225A
(en)
|
1990-01-12 |
1998-07-14 |
Stratagene |
Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules
|
|
US5314995A
(en)
|
1990-01-22 |
1994-05-24 |
Oncogen |
Therapeutic interleukin-2-antibody based fusion proteins
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
US5349053A
(en)
|
1990-06-01 |
1994-09-20 |
Protein Design Labs, Inc. |
Chimeric ligand/immunoglobulin molecules and their uses
|
|
FI85768C
(fi)
|
1990-07-04 |
1992-05-25 |
Valtion Teknillinen |
Foerfarande foer utfoerning av ytplasmonresonansmaetning samt i foerfarandet anvaendbar givare.
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US5698426A
(en)
|
1990-09-28 |
1997-12-16 |
Ixsys, Incorporated |
Surface expression libraries of heteromeric receptors
|
|
WO1992009690A2
(en)
|
1990-12-03 |
1992-06-11 |
Genentech, Inc. |
Enrichment method for variant proteins with altered binding properties
|
|
AU643109B2
(en)
|
1990-12-14 |
1993-11-04 |
Cell Genesys, Inc. |
Chimeric chains for receptor-associated signal transduction pathways
|
|
DE69233750D1
(de)
|
1991-04-10 |
2009-01-02 |
Scripps Research Inst |
Bibliotheken heterodimerer Rezeptoren mittels Phagemiden
|
|
JPH06507404A
(ja)
|
1991-05-01 |
1994-08-25 |
ヘンリー エム.ジャクソン ファウンデイション フォー ザ アドバンスメント オブ ミリタリー メディスン |
感染性の呼吸性疾患の治療方法
|
|
DE69233482T2
(de)
|
1991-05-17 |
2006-01-12 |
Merck & Co., Inc. |
Verfahren zur Verminderung der Immunogenität der variablen Antikörperdomänen
|
|
DE69110032T2
(de)
|
1991-06-08 |
1995-12-21 |
Hewlett Packard Gmbh |
Verfahren und Gerät zur Feststellung und/oder Konzentrationsbestimmung von Biomolekülen.
|
|
EP0590058B1
(en)
|
1991-06-14 |
2003-11-26 |
Genentech, Inc. |
HUMANIZED Heregulin ANTIBODy
|
|
US5565332A
(en)
|
1991-09-23 |
1996-10-15 |
Medical Research Council |
Production of chimeric antibodies - a combinatorial approach
|
|
ATE408012T1
(de)
|
1991-12-02 |
2008-09-15 |
Medical Res Council |
Herstellung von autoantikörpern auf phagenoberflächen ausgehend von antikörpersegmentbibliotheken
|
|
DE69233204T2
(de)
|
1991-12-13 |
2004-07-15 |
Xoma Corp., Berkeley |
Verfahren und materialien zur herstellung von modifizierten variablen antikörperdomänen und ihre therapeutische verwendung
|
|
US5622929A
(en)
|
1992-01-23 |
1997-04-22 |
Bristol-Myers Squibb Company |
Thioether conjugates
|
|
GB9203459D0
(en)
|
1992-02-19 |
1992-04-08 |
Scotgen Ltd |
Antibodies with germ-line variable regions
|
|
US5714350A
(en)
|
1992-03-09 |
1998-02-03 |
Protein Design Labs, Inc. |
Increasing antibody affinity by altering glycosylation in the immunoglobulin variable region
|
|
US5733743A
(en)
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
|
US5447851B1
(en)
|
1992-04-02 |
1999-07-06 |
Univ Texas System Board Of |
Dna encoding a chimeric polypeptide comprising the extracellular domain of tnf receptor fused to igg vectors and host cells
|
|
ZA932522B
(en)
|
1992-04-10 |
1993-12-20 |
Res Dev Foundation |
Immunotoxins directed against c-erbB-2(HER/neu) related surface antigens
|
|
WO1993023434A2
(en)
|
1992-05-19 |
1993-11-25 |
Xoma Corporation |
Bpi-immunoglobulin fusion proteins
|
|
US6005079A
(en)
|
1992-08-21 |
1999-12-21 |
Vrije Universiteit Brussels |
Immunoglobulins devoid of light chains
|
|
EP0656946B2
(en)
|
1992-08-21 |
2010-03-31 |
Vrije Universiteit Brussel |
Immunoglobulins devoid of light chains
|
|
EP0749475A4
(en)
|
1992-08-26 |
1997-05-07 |
Harvard College |
USE OF CYTOKINE IP-10 AS ANTI-TUMOR AGENT
|
|
US5639641A
(en)
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
|
WO1994009817A1
(en)
|
1992-11-04 |
1994-05-11 |
City Of Hope |
Novel antibody construct
|
|
US5934272A
(en)
|
1993-01-29 |
1999-08-10 |
Aradigm Corporation |
Device and method of creating aerosolized mist of respiratory drug
|
|
DE69427974T2
(de)
|
1993-04-29 |
2001-12-06 |
Unilever N.V., Rotterdam |
Herstellung von antikörpern oder funktionstüchtig gemachten teilen davon, abgeleitet von schweren ketten von immunglobulinen von camelidae
|
|
WO1995015982A2
(en)
|
1993-12-08 |
1995-06-15 |
Genzyme Corporation |
Process for generating specific antibodies
|
|
DK1231268T3
(da)
|
1994-01-31 |
2005-11-21 |
Univ Boston |
Polyklonale antistofbiblioteker
|
|
US5837458A
(en)
|
1994-02-17 |
1998-11-17 |
Maxygen, Inc. |
Methods and compositions for cellular and metabolic engineering
|
|
US5834252A
(en)
|
1995-04-18 |
1998-11-10 |
Glaxo Group Limited |
End-complementary polymerase reaction
|
|
US5605793A
(en)
|
1994-02-17 |
1997-02-25 |
Affymax Technologies N.V. |
Methods for in vitro recombination
|
|
US5516637A
(en)
|
1994-06-10 |
1996-05-14 |
Dade International Inc. |
Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage
|
|
AU3382595A
(en)
|
1994-07-29 |
1996-03-04 |
Smithkline Beecham Corporation |
Novel compounds
|
|
US6962686B2
(en)
|
1994-10-12 |
2005-11-08 |
California Institute Of Technology |
Cell-specific gene delivery vehicles
|
|
US6019968A
(en)
|
1995-04-14 |
2000-02-01 |
Inhale Therapeutic Systems, Inc. |
Dispersible antibody compositions and methods for their preparation and use
|
|
JP3517495B2
(ja)
|
1995-10-12 |
2004-04-12 |
トヨタ自動車株式会社 |
金型鋳造用離型剤
|
|
JP2978435B2
(ja)
|
1996-01-24 |
1999-11-15 |
チッソ株式会社 |
アクリロキシプロピルシランの製造方法
|
|
ATE508733T1
(de)
|
1996-03-04 |
2011-05-15 |
Penn State Res Found |
Materialien und verfahren zur steigerung der zellulären internalisierung
|
|
WO1997033899A1
(en)
|
1996-03-14 |
1997-09-18 |
Human Genome Sciences, Inc. |
Apoptosis inducing molecule i
|
|
WO1997034631A1
(en)
|
1996-03-18 |
1997-09-25 |
Board Of Regents, The University Of Texas System |
Immunoglobin-like domains with increased half lives
|
|
EP0904278A4
(en)
|
1996-03-22 |
1999-09-15 |
Human Genome Sciences Inc |
MOLECULE II INDUCER OF APOPTOSIS
|
|
US5985309A
(en)
|
1996-05-24 |
1999-11-16 |
Massachusetts Institute Of Technology |
Preparation of particles for inhalation
|
|
US5855913A
(en)
|
1997-01-16 |
1999-01-05 |
Massachusetts Instite Of Technology |
Particles incorporating surfactants for pulmonary drug delivery
|
|
US5874064A
(en)
|
1996-05-24 |
1999-02-23 |
Massachusetts Institute Of Technology |
Aerodynamically light particles for pulmonary drug delivery
|
|
GB9623820D0
(en)
|
1996-11-16 |
1997-01-08 |
Secr Defence |
Surface plasma resonance sensor
|
|
WO1998023289A1
(en)
|
1996-11-27 |
1998-06-04 |
The General Hospital Corporation |
MODULATION OF IgG BINDING TO FcRn
|
|
WO1998031346A1
(en)
|
1997-01-16 |
1998-07-23 |
Massachusetts Institute Of Technology |
Preparation of particles for inhalation
|
|
US6277375B1
(en)
|
1997-03-03 |
2001-08-21 |
Board Of Regents, The University Of Texas System |
Immunoglobulin-like domains with increased half-lives
|
|
US5896619A
(en)
|
1997-08-29 |
1999-04-27 |
General Electric Company |
Refrigerator door hinge and closure mechanism
|
|
ES2303358T3
(es)
|
1997-11-03 |
2008-08-01 |
Human Genome Sciences, Inc. |
Vegi, un inhibidor de la angiogenesis y el crecimiento tumoral.
|
|
DE19923820C2
(de)
|
1998-05-20 |
2001-05-10 |
Graffinity Pharm Design Gmbh |
SPR-Sensor zur gleichzeitigen Erfassung einer Vielzahl von in fluider Form vorliegenden Proben
|
|
US6289286B1
(en)
|
1998-05-29 |
2001-09-11 |
Biacore Ab |
Surface regeneration of biosensors and characterization of biomolecules associated therewith
|
|
CA2336139C
(en)
|
1998-06-24 |
2008-10-14 |
Advanced Inhalation Research, Inc. |
Large porous particles emitted from an inhaler
|
|
US6311415B1
(en)
|
1998-09-14 |
2001-11-06 |
Lind Shoe Company |
Bowling shoe with replaceable tip
|
|
US6319691B1
(en)
|
1999-06-15 |
2001-11-20 |
Usa Universe Bioengineering, Inc. |
Fusion proteins comprising IFN-alpha2b and TM-alpha1
|
|
US6346249B1
(en)
*
|
1999-10-22 |
2002-02-12 |
Ludwig Institute For Cancer Research |
Methods for reducing the effects of cancers that express A33 antigen using A33 antigen specific immunoglobulin products
|
|
AU1102401A
(en)
|
1999-10-22 |
2001-05-08 |
Ludwig Institute For Cancer Research |
Methods for reducing the effects of cancers that express a33 antigen using a33 antigen specific immunoglobulin products
|
|
DK1517921T3
(da)
*
|
2002-06-28 |
2006-10-09 |
Domantis Ltd |
Immunglobulin-enkeltvariable antigen-bindende domæner og dobbeltspecifikke konstruktioner deraf
|
|
JP2005535341A
(ja)
*
|
2002-08-15 |
2005-11-24 |
エピトミスク インコーポレーティッド |
ヒト化ウサギ抗体
|
|
JP3803790B2
(ja)
|
2003-02-17 |
2006-08-02 |
株式会社東北テクノアーチ |
新規なダイアボディ型二重特異性抗体
|
|
US20050281828A1
(en)
*
|
2003-03-04 |
2005-12-22 |
Bowdish Katherine S |
Method of treating autoimmune disease by inducing antigen presentation by tolerance inducing antigen presenting cells
|
|
EP1605974B1
(en)
|
2003-03-04 |
2014-11-12 |
Alexion Pharmaceuticals, Inc. |
Method of treating autoimmune disease by inducing antigen presentation by tolerance inducing antigen presenting cells
|
|
JPWO2004087763A1
(ja)
|
2003-03-31 |
2006-07-27 |
中外製薬株式会社 |
Cd22に対する改変抗体およびその利用
|
|
US20050048578A1
(en)
*
|
2003-06-26 |
2005-03-03 |
Epitomics, Inc. |
Methods of screening for monoclonal antibodies with desirable activity
|
|
CA2533830A1
(en)
|
2003-08-07 |
2005-02-24 |
Epitomics, Inc. |
Methods for humanizing rabbit monoclonal antibodies
|
|
US7217348B2
(en)
|
2003-08-21 |
2007-05-15 |
Rensselaer Polytechnic Institute |
Methods of identifying kinetically stable proteins
|
|
US7431927B2
(en)
*
|
2005-03-24 |
2008-10-07 |
Epitomics, Inc. |
TNFα-neutralizing antibodies
|
|
AU2006236439B2
(en)
|
2005-04-15 |
2012-05-03 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
|
WO2008004834A1
(en)
|
2006-07-06 |
2008-01-10 |
Isu Abxis Co., Ltd |
Humanized monoclonal antibody highly binding to epidermal growth factor receptor, egf receptor
|
|
TWI345791B
(en)
*
|
2006-07-31 |
2011-07-21 |
Sandisk 3D Llc |
Method and apparatus for memory array incorporating two data busses for memory array block selection
|