JP5781090B2 - チアゾロ［５，４−ｄ］ピリミジン及び農薬としてのそれらの使用 - Google Patents
チアゾロ［５，４−ｄ］ピリミジン及び農薬としてのそれらの使用 Download PDFInfo
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- JP5781090B2 JP5781090B2 JP2012548116A JP2012548116A JP5781090B2 JP 5781090 B2 JP5781090 B2 JP 5781090B2 JP 2012548116 A JP2012548116 A JP 2012548116A JP 2012548116 A JP2012548116 A JP 2012548116A JP 5781090 B2 JP5781090 B2 JP 5781090B2
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- Prior art keywords
- alkyl
- spp
- compound
- phenyl
- alkoxy
- Prior art date
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- 239000000575 pesticide Substances 0.000 title claims description 25
- CDGFEINVQHEUQV-UHFFFAOYSA-N [1,3]thiazolo[5,4-d]pyrimidine Chemical class N1=CN=C2SC=NC2=C1 CDGFEINVQHEUQV-UHFFFAOYSA-N 0.000 title description 2
- 150000001875 compounds Chemical class 0.000 claims description 171
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- 125000000217 alkyl group Chemical group 0.000 claims description 76
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- 125000003545 alkoxy group Chemical group 0.000 claims description 31
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- 125000001188 haloalkyl group Chemical group 0.000 claims description 25
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- WCLDITPGPXSPGV-UHFFFAOYSA-N tricamba Chemical compound COC1=C(Cl)C=C(Cl)C(Cl)=C1C(O)=O WCLDITPGPXSPGV-UHFFFAOYSA-N 0.000 description 1
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- HSMVPDGQOIQYSR-KGENOOAVSA-N triflumizole Chemical compound C1=CN=CN1C(/COCCC)=N/C1=CC=C(Cl)C=C1C(F)(F)F HSMVPDGQOIQYSR-KGENOOAVSA-N 0.000 description 1
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- ZSDSQXJSNMTJDA-UHFFFAOYSA-N trifluralin Chemical compound CCCN(CCC)C1=C([N+]([O-])=O)C=C(C(F)(F)F)C=C1[N+]([O-])=O ZSDSQXJSNMTJDA-UHFFFAOYSA-N 0.000 description 1
- AKTQJCBOGPBERP-UHFFFAOYSA-N triflusulfuron Chemical compound FC(F)(F)COC1=NC(N(C)C)=NC(NC(=O)NS(=O)(=O)C=2C(=CC=CC=2C)C(O)=O)=N1 AKTQJCBOGPBERP-UHFFFAOYSA-N 0.000 description 1
- KVEQCVKVIFQSGC-UHFFFAOYSA-N tritosulfuron Chemical compound FC(F)(F)C1=NC(OC)=NC(NC(=O)NS(=O)(=O)C=2C(=CC=CC=2)C(F)(F)F)=N1 KVEQCVKVIFQSGC-UHFFFAOYSA-N 0.000 description 1
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- UNJPMQYPLYFGJD-UHFFFAOYSA-L zinc cadmium(2+) dioxido(dioxo)chromium sulfate Chemical compound S(=O)(=O)([O-])[O-].[Cr](=O)(=O)([O-])[O-].[Zn+2].[Cd+2] UNJPMQYPLYFGJD-UHFFFAOYSA-L 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
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- General Chemical & Material Sciences (AREA)
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- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
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- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
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| US29301410P | 2010-01-07 | 2010-01-07 | |
| US61/293,014 | 2010-01-07 | ||
| PCT/US2011/020351 WO2011085084A1 (en) | 2010-01-07 | 2011-01-06 | THIAZOLO[5,4-d] PYRIMIDINES AND THEIR USE AS AGROCHEMICALS |
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| JP2013516476A JP2013516476A (ja) | 2013-05-13 |
| JP5781090B2 true JP5781090B2 (ja) | 2015-09-16 |
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| UA (1) | UA109780C2 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20140754T2 (hr) | 2009-06-29 | 2015-07-17 | Incyte Corporation | Pirimidinoni kao inhibitori pi3k |
| WO2013012918A1 (en) | 2011-07-19 | 2013-01-24 | Infinity Pharmaceuticals Inc. | Heterocyclic compounds and uses thereof |
| JPWO2013031694A1 (ja) * | 2011-08-26 | 2015-03-23 | 富山化学工業株式会社 | アミン化合物またはその塩 |
| LT3196202T (lt) | 2011-09-02 | 2019-07-10 | Incyte Holdings Corporation | Heterociklilaminai, kaip pi3k slopikliai |
| CA2862346A1 (en) | 2012-02-03 | 2013-08-08 | Basf Se | Fungicidal pyrimidine compounds |
| JP2015511940A (ja) | 2012-02-03 | 2015-04-23 | ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ | 殺菌性ピリミジン化合物 |
| WO2013135672A1 (en) | 2012-03-13 | 2013-09-19 | Basf Se | Fungicidal pyrimidine compounds |
| AR090548A1 (es) | 2012-04-02 | 2014-11-19 | Incyte Corp | Azaheterociclobencilaminas biciclicas como inhibidores de pi3k |
| CN103668956B (zh) * | 2012-09-21 | 2015-08-12 | 上海韬鸿化工科技有限公司 | 防螨虫整理剂、织物的防螨虫整理方法及防螨虫织物 |
| EP3409115A3 (en) * | 2013-03-15 | 2019-02-27 | The Regents of The University of California | Methods for identifying arthropod repellents, and compounds and compositions identified by such methods |
| US10077277B2 (en) | 2014-06-11 | 2018-09-18 | Incyte Corporation | Bicyclic heteroarylaminoalkyl phenyl derivatives as PI3K inhibitors |
| CN105594748A (zh) * | 2014-10-15 | 2016-05-25 | 浙江新安化工集团股份有限公司 | 一种精准定向、高效的防治鳞翅目害虫的杀虫组合物及其使用方法 |
| CN104391070B (zh) * | 2014-12-05 | 2016-06-08 | 山东省城市供排水水质监测中心 | 一种水中烷基汞的检测方法 |
| CN117736209A (zh) | 2015-02-27 | 2024-03-22 | 因赛特控股公司 | Pi3k抑制剂的盐及其制备方法 |
| US20160272612A1 (en) | 2015-03-18 | 2016-09-22 | The Regents Of The University Of California | Anthropod repellent chemicals |
| WO2016183063A1 (en) | 2015-05-11 | 2016-11-17 | Incyte Corporation | Crystalline forms of a pi3k inhibitor |
| CN105606755A (zh) * | 2016-01-30 | 2016-05-25 | 郭庆龙 | 一种胺苯吡唑酮残留量的gc-nci-ms测定方法 |
| EP3575286B1 (en) | 2017-01-26 | 2022-05-11 | Mitsui Chemicals Agro, Inc. | Pyridone compound and bactericide for agricultural and horticultural use, which uses said compound as active ingredient |
| WO2018190351A1 (ja) | 2017-04-10 | 2018-10-18 | 三井化学アグロ株式会社 | ピリドン化合物およびそれを有効成分とする農園芸用殺菌剤 |
| CA3059675A1 (en) | 2017-04-10 | 2018-10-18 | Mitsui Chemicals Agro, Inc. | Pyridone compounds and agricultural and horticultural fungicides comprising the same as active ingredients |
| US11178870B2 (en) | 2017-04-11 | 2021-11-23 | Mitsui Chemicals Agro, Inc. | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients |
| EP3636636B1 (en) | 2017-06-08 | 2022-07-06 | Mitsui Chemicals Agro, Inc. | Pyridone compound and agricultural and horticultural fungicide |
| PE20211208A1 (es) | 2018-06-01 | 2021-07-05 | Incyte Corp | Regimen de dosificacion para el tratamiento de trastornos relacionados con pi3k |
| US12114658B2 (en) | 2018-07-25 | 2024-10-15 | Mitsui Chemicals Crop & Life Solutions, Inc. | Compounds having a nitrogen-containing unsaturated six-membered ring and agricultural and horticultural fungicides containing the same as active ingredients |
| CN115003160B (zh) | 2020-02-11 | 2024-04-30 | 先正达农作物保护股份公司 | 控制真菌的方法 |
| CN112010848B (zh) * | 2020-09-29 | 2021-12-24 | 南通大学 | 含三氟甲基吡啶联芳氧基结构的1,3,4-噁二唑类化合物的制备方法和应用 |
| CN116250525B (zh) * | 2023-03-08 | 2024-12-24 | 内蒙古民族大学 | 一种小型哺乳类剥制标本安全防腐剂及其制备方法 |
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| US3309359A (en) | 1965-10-22 | 1967-03-14 | Hoffmann La Roche | N-mono-acyl-5-fluorocytosine derivatives and process |
| US3368938A (en) | 1966-01-13 | 1968-02-13 | Hoffmann La Roche | Controlling fungi with 5-fluorocytosine |
| US3868373A (en) | 1970-01-27 | 1975-02-25 | Hoffmann La Roche | 4-Amino-5-fluoro-2-tri(lower alkyl) silyloxypyrimidines |
| CH579057A5 (enExample) | 1973-09-07 | 1976-08-31 | Hoffmann La Roche | |
| FR2530636A1 (fr) | 1982-07-23 | 1984-01-27 | Rhone Poulenc Agrochimie | Nouveaux derives de la tetrahydro-2,3,6,7 5h-thiazolo (3,2-a) pyrimidine, leur preparation et leur utilisation comme herbicides |
| EP0139613A1 (de) | 1983-08-29 | 1985-05-02 | Ciba-Geigy Ag | N-(2-Nitrophenyl)-4-aminopyrimidin-Derivate, deren Herstellung und Verwendung |
| US4845081A (en) | 1984-10-18 | 1989-07-04 | University Of Florida | Aminomethyl derivatives of biologically active substances, and enhanced delivery thereof across topical membranes |
| EP0332579B1 (de) | 1988-03-09 | 1994-08-10 | Ciba-Geigy Ag | Mittel zum Schutz von Pflanzen gegen Krankheiten |
| DE3821711A1 (de) * | 1988-06-28 | 1990-02-08 | Bayer Ag | Thiazolopyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als schaedlingsbekaempfungsmittel |
| US5034393A (en) | 1989-07-27 | 1991-07-23 | Dowelanco | Fungicidal use of pyridopyrimidine, pteridine, pyrimidopyrimidine, pyrimidopyridazine, and pyrimido-1,2,4-triazine derivatives |
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| US5326766A (en) | 1992-08-19 | 1994-07-05 | Dreikorn Barry A | 4-(2-(4-(2-pyridinyloxy)phenyl)ethoxy)quinazoline and analogues thereof |
| CN1105113C (zh) | 1995-07-05 | 2003-04-09 | 纳幕尔杜邦公司 | 杀真菌嘧啶酮 |
| TR199801813T2 (xx) | 1996-03-11 | 1998-12-21 | Novartis Ag | B�cek �ld�r�c� olarak pirimidin-4- on t�revleri. |
| HRP970239B1 (en) | 1997-05-09 | 2004-04-30 | Inst Ru Er Bouekovic | Process for the preparation of sulfonyl-pyrimidine derivatives with antitumor activity |
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| SI2389375T1 (sl) | 2009-01-23 | 2015-11-30 | Euro-Celtique S.A. | Derivati hidroksamske kisline |
| CN101613362B (zh) * | 2009-07-31 | 2011-11-16 | 南京工业大学 | 3-羰基-6-乙氧甲酰基-噻唑并嘧啶类化合物及其合成方法和用途 |
| AU2010279411B2 (en) | 2009-08-07 | 2014-10-23 | Adama Makhteshim Ltd. | N1-sulfonyl-5-fluoropyrimidinone derivatives |
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- 2011-01-06 CA CA2786250A patent/CA2786250A1/en not_active Abandoned
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Also Published As
| Publication number | Publication date |
|---|---|
| PL2521452T3 (pl) | 2015-05-29 |
| JP2013516476A (ja) | 2013-05-13 |
| EP2521452A1 (en) | 2012-11-14 |
| RU2012133570A (ru) | 2014-02-20 |
| EP2521452A4 (en) | 2013-07-03 |
| US20110166164A1 (en) | 2011-07-07 |
| IN2012DN06323A (enExample) | 2015-10-02 |
| RU2547721C2 (ru) | 2015-04-10 |
| US8921382B2 (en) | 2014-12-30 |
| EP2521452B1 (en) | 2014-12-24 |
| BR112012016866A2 (pt) | 2015-09-01 |
| HK1176236A1 (en) | 2013-07-26 |
| PT2521452E (pt) | 2015-02-24 |
| CA2786250A1 (en) | 2011-07-14 |
| CO6612238A2 (es) | 2013-02-01 |
| ZA201204871B (en) | 2013-09-25 |
| CL2012001851A1 (es) | 2012-12-14 |
| KR20120115538A (ko) | 2012-10-18 |
| MX2012007954A (es) | 2012-08-03 |
| KR101814835B1 (ko) | 2018-01-04 |
| UA109780C2 (uk) | 2015-10-12 |
| ES2529247T3 (es) | 2015-02-18 |
| CN102791135B (zh) | 2015-05-20 |
| CN102791135A (zh) | 2012-11-21 |
| WO2011085084A1 (en) | 2011-07-14 |
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