JP5771696B2 - フロー式粒子分析器のための二重フィードバック真空流体工学 - Google Patents

フロー式粒子分析器のための二重フィードバック真空流体工学 Download PDF

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JP5771696B2
JP5771696B2 JP2013536693A JP2013536693A JP5771696B2 JP 5771696 B2 JP5771696 B2 JP 5771696B2 JP 2013536693 A JP2013536693 A JP 2013536693A JP 2013536693 A JP2013536693 A JP 2013536693A JP 5771696 B2 JP5771696 B2 JP 5771696B2
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fluid
flow
sample
resistance
sheath
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JP2014503792A (ja
JP2014503792A5 (https=
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バレーン デービッド
バレーン デービッド
オー．ノートン ピアス
オー．ノートン ピアス
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Becton Dickinson and Co
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G01N15/1409—Handling samples, e.g. injecting samples
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/0318—Processes
    • Y10T137/0324—With control of flow by a condition or characteristic of a fluid
    • Y10T137/0379—By fluid pressure

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  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Immunology (AREA)
  • Health & Medical Sciences (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Optical Measuring Cells (AREA)
  • Fluid Mechanics (AREA)
  • Engineering & Computer Science (AREA)
  • Automation & Control Theory (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
JP2013536693A 2010-10-29 2011-10-24 フロー式粒子分析器のための二重フィードバック真空流体工学 Active JP5771696B2 (ja)

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US40799010P 2010-10-29 2010-10-29
PCT/US2011/057445 WO2012058142A1 (en) 2010-10-29 2011-10-24 Dual feedback vacuum fluidics for a flow-type particle analyzer

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JP2014503792A JP2014503792A (ja) 2014-02-13
JP2014503792A5 JP2014503792A5 (https=) 2014-10-16
JP5771696B2 true JP5771696B2 (ja) 2015-09-02

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US (2) US8528427B2 (https=)
EP (1) EP2633283B1 (https=)
JP (1) JP5771696B2 (https=)
CN (1) CN103201611B (https=)
AU (1) AU2011320713B2 (https=)
ES (1) ES2732355T3 (https=)
SG (1) SG189532A1 (https=)
WO (1) WO2012058142A1 (https=)
ZA (1) ZA201302955B (https=)

Families Citing this family (115)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004285960A1 (en) 2003-10-30 2005-05-12 Cytonome/St, Llc Multilayer hydrodynamic sheath flow structure
CA2764522C (en) * 2009-07-02 2015-09-15 The Governors Of The University Of Alberta Particle classifier
CN102792147B (zh) * 2010-03-10 2015-05-13 贝克曼考尔特公司 在颗粒分析器中产生脉冲参数
CN104813157A (zh) * 2012-11-29 2015-07-29 细胞流有限责任公司 流体系统和方法
NZ711384A (en) 2013-03-14 2018-06-29 Cytonome St Llc Hydrodynamic focusing apparatus and methods
US9279750B2 (en) * 2013-03-15 2016-03-08 Iris International, Inc. Method and composition for staining and sample processing
US9372143B2 (en) * 2013-05-15 2016-06-21 Captl Llc Scanning image flow cytometer
US20150107711A1 (en) * 2013-10-21 2015-04-23 Cytoflow, Llc Cytometer flowcell
CN103837462B (zh) * 2014-03-03 2016-10-05 中国科学院苏州生物医学工程技术研究所 一种小型流式细胞仪液路系统
JP5873126B2 (ja) * 2014-04-04 2016-03-01 日本電信電話株式会社 送液方法および送液システム
CN107003225B (zh) 2014-12-04 2020-08-18 贝克顿·迪金森公司 流式细胞术细胞分选系统及其使用方法
WO2016093970A1 (en) 2014-12-10 2016-06-16 Becton, Dickinson And Company Methods for optically aligning light collection components and optically aligned light collection systems thereof
WO2016100954A1 (en) 2014-12-19 2016-06-23 Captl Llc Flow cytometry using hydrodynamically planar flow
ES2987551T3 (es) 2015-02-18 2024-11-15 Becton Dickinson Co Sistemas de detección óptica y métodos de uso de los mismos
EP3311135B1 (en) 2015-06-17 2023-11-01 Becton, Dickinson and Company Optical detector scatter cap assembly having a removable scatter bar and methods of using the same
US10036698B2 (en) 2015-06-19 2018-07-31 Captl Llc Time-sequential cytometry
CN108474728B (zh) 2015-10-13 2022-04-26 贝克顿·迪金森公司 多模态荧光成像流式细胞术系统
EP3426296A4 (en) 2016-03-10 2019-11-20 Becton, Dickinson and Company METHOD OF EVALUATING A CELLULAR SAMPLE FOR HER-2 / NEU EXPRESSION AND COMPOSITIONS FOR IMPLEMENTING THEREOF
JP7130562B2 (ja) 2016-03-17 2022-09-05 ベクトン・ディキンソン・アンド・カンパニー ハイスループット蛍光フローサイトメーターを用いる細胞選別
CN109070083A (zh) 2016-04-22 2018-12-21 贝克顿迪金森公司 用于阵列产生的高密度沉积
CN109477784B (zh) 2016-05-12 2022-04-01 Bd生物科学公司 具有增强图像分辨率的荧光成像流式细胞术
CN109477785B (zh) 2016-09-13 2022-09-27 贝克顿·迪金森公司 具有光学均衡的流式细胞仪
CN109073530B (zh) 2016-10-03 2022-04-26 贝克顿·迪金森公司 用于确定流式细胞仪中的流体流的液滴延迟的方法和系统
EP3541536B1 (en) 2016-11-19 2025-10-22 Cytek Biosciences, Inc. Flow cytometry systems with stepper flow control valve
US10436697B2 (en) * 2016-11-19 2019-10-08 Cytek Biosciences, Inc. Flow cytometery system with fluidics control system
WO2018111536A1 (en) 2016-12-14 2018-06-21 Becton, Dickinson And Company Methods and compositions for obtaining a tuberculosis assessment in a subject
EP3579974A4 (en) 2017-02-08 2020-12-30 Becton, Dickinson and Company REACTIVE DEVICES FOR DRIED COLORANT AND THEIR MANUFACTURING AND USE PROCEDURES
EP3586104A4 (en) 2017-02-27 2020-12-16 Becton, Dickinson and Company LIGHT DETECTION SYSTEMS AND THEIR OPERATING PROCEDURES
US10613020B2 (en) * 2017-08-10 2020-04-07 The Boeing Company Burr detection systems and methods
US10801617B2 (en) 2018-01-05 2020-10-13 Cnh Industrial America Llc Propel system with active pump displacement control for balancing propel pump pressures in agricultural vehicles
AU2019212778A1 (en) 2018-01-23 2020-08-13 Becton, Dickinson And Company Systems for dynamic light detection obscuration and methods for using thereof
CN119220109A (zh) 2018-03-30 2024-12-31 贝克顿·迪金森公司 含侧基发色团的水溶性聚合染料
US11275075B2 (en) 2018-04-27 2022-03-15 Becton, Dickinson And Company Collection systems for flow cytometrically sorted samples and methods of using the same
EP3811055A4 (en) 2018-06-19 2022-08-10 Becton, Dickinson and Company VARIABLE MULTIPLEXER SWITCHES FOR DETECTOR ARRAYS, SYSTEMS, AND METHODS OF USE THEREOF
WO2020005430A1 (en) 2018-06-28 2020-01-02 Becton, Dickinson And Company Integrated pre-amplification light detection systems and methods of use thereof
JP7500540B2 (ja) * 2018-08-15 2024-06-17 ベクトン・ディキンソン・アンド・カンパニー フロー式粒子分析器のための流量および真空制御式流体管理システム
US11327003B2 (en) 2018-08-30 2022-05-10 Becton, Dickinson And Company Characterization and sorting for particle analyzers
CN109357991B (zh) * 2018-09-27 2020-05-26 清华大学 一种免标记原理的质谱流式细胞进样与离子化装置
EP3874254B1 (en) 2018-10-30 2025-04-30 Becton, Dickinson and Company Particle sorting module with alignment window, systems and methods of use thereof
US11237093B2 (en) 2018-12-10 2022-02-01 Bio-Rad Laboratories, Inc. External fluidics system for flow cytometer
JP7528087B2 (ja) 2018-12-28 2024-08-05 ベクトン・ディキンソン・アンド・カンパニー サンプルの蛍光物質をスペクトル的に分解する方法及びシステム
CN113302470B (zh) 2019-02-08 2024-11-08 贝克顿·迪金森公司 液滴分选决策模块、系统及其使用方法
JP7416821B2 (ja) 2019-03-22 2024-01-17 ベクトン・ディキンソン・アンド・カンパニー 高周波多重励起データを使用した蛍光イメージングのスペクトルアンミックス
JP7466563B2 (ja) 2019-03-29 2024-04-15 ベクトン・ディキンソン・アンド・カンパニー 粒子の区別に使用するためのパラメータ
JP7175231B2 (ja) * 2019-04-08 2022-11-18 アークレイ株式会社 検体の分析方法及び検体の分析装置
CN111796111B (zh) * 2019-04-08 2025-11-21 爱科来株式会社 送液方法和分析装置
JP7312135B2 (ja) * 2019-04-08 2023-07-20 アークレイ株式会社 送液方法及び分析装置
JP7504127B2 (ja) 2019-05-14 2024-06-21 ベクトン・ディキンソン・アンド・カンパニー イメージングフローサイトメトリーのための位相キャリブレーション
IL287195B2 (en) 2019-05-30 2025-07-01 Becton Dickinson Co Phase correction of multiplexed radio frequency signals
EP3997439A4 (en) 2019-07-10 2023-07-19 Becton, Dickinson and Company Reconfigurable integrated circuits for adjusting cell sorting classification
US12571718B2 (en) * 2019-09-20 2026-03-10 Kansas State University Research Foundation Methods and apparatus for contactless orthographic imaging of aerosol particles
WO2021101692A1 (en) 2019-11-20 2021-05-27 Becton, Dickinson And Company A light detection module with adjustable sensitivity
CN115053135B (zh) 2019-12-20 2026-03-27 贝克顿·迪金森公司 用于对细胞外囊泡表面标志物进行定量的方法及用于实施该方法的组合物
JP7663587B2 (ja) 2020-01-31 2025-04-16 ベクトン・ディキンソン・アンド・カンパニー 訓練ゲートを調整してフローサイトメータデータに適応させるための方法およびシステム
JP2023513217A (ja) 2020-02-07 2023-03-30 ベクトン・ディキンソン・アンド・カンパニー クラスタ化波長分割光検出システム及びその使用方法
US11709125B2 (en) 2020-02-19 2023-07-25 Becton, Dickinson And Company Strobed laser excitation systems and methods of use thereof
CN115151811B (zh) 2020-02-26 2026-04-03 贝克顿·迪金森公司 具有辅助光散射检测器的光检测系统及其使用方法
EP4111169A4 (en) 2020-02-27 2023-08-09 Becton, Dickinson and Company METHODS FOR IDENTIFYING SATURATED DATA SIGNALS IN CELL SORTING AND RELATED SYSTEMS
US11874213B2 (en) 2020-03-17 2024-01-16 Becton, Dickinson And Company Gain matched amplifiers for light detection
US12510461B2 (en) 2020-04-16 2025-12-30 Becton, Dickinson And Company Systems for light detection array multiplexing and methods for same
WO2021221884A1 (en) 2020-04-28 2021-11-04 Becton, Dickinson And Company Method for index sorting unique phenotypes and systems for same
EP4143536B1 (en) 2020-04-29 2025-08-20 Becton, Dickinson and Company Methods for modulation and synchronous detection in a flow cytometer and systems for same
CN115917315A (zh) 2020-05-05 2023-04-04 贝克顿·迪金森公司 用于确定流式细胞仪中检测器增益的方法
US11674879B2 (en) 2020-05-06 2023-06-13 Becton, Dickinson And Company Methods and systems for characterizing spillover spreading in flow cytometer data
WO2021236339A1 (en) 2020-05-18 2021-11-25 Becton, Dickinson And Company Resolution indices for detecting heterogeneity in data and methods of use thereof
WO2021257144A1 (en) 2020-06-19 2021-12-23 Becton, Dickinson And Company Flow cytometer with adjustable positional offset sort deflection plates and methods of using the same
WO2021262359A1 (en) 2020-06-24 2021-12-30 Becton, Dickinson And Company Flow cytometric droplet dispensing systems and methods for using the same
EP4172592B1 (en) 2020-06-26 2025-07-16 Becton, Dickinson and Company Dual excitation beams for irradiating a sample in a flow stream and methods for using same
US11965813B2 (en) 2020-08-03 2024-04-23 Cytek Biosciences, Inc. Methods and apparatus for central source pressure-based cytometer fluidics system
EP4610628A3 (en) 2020-09-22 2025-11-19 Becton, Dickinson And Company Methods for continuous measurement of baseline noise in a flow cytometer and systems for same
US20220120658A1 (en) 2020-10-20 2022-04-21 Becton, Dickinson And Company Flow cytometers including tilted beam shaping optical components, and methods of using the same
US12566123B2 (en) 2020-10-30 2026-03-03 Becton, Dickinson And Company Method and systems for characterizing and encoding a light detection system
JP7766690B2 (ja) 2020-11-19 2025-11-10 ベクトン・ディキンソン・アンド・カンパニー 機械学習分析のためのサイトメトリックデータの最適なスケーリング方法及びそのシステム
US11959849B2 (en) 2021-01-13 2024-04-16 Becton, Dickinson And Company Flow cytometers including light collection enhancers, and methods of using the same
US20220236164A1 (en) 2021-01-25 2022-07-28 Becton, Dickinson And Company Method and systems for determing drop delay using scatter signals across spatially separated lasers
CN214895849U (zh) 2021-01-28 2021-11-26 贝克曼库尔特生物科技（苏州）有限公司 气泡检测装置和样本处理仪
EP4288757A4 (en) 2021-02-04 2024-07-31 Becton, Dickinson and Company LIGHT-INTEGRATED INTERROGATION MODULES AND METHODS OF USE THEREOF
US12285761B2 (en) 2021-02-05 2025-04-29 Cytek Biosciences, Inc. Integrated air filtering and conditioning of droplet chamber in a compact cell sorter
US12379301B2 (en) 2021-03-24 2025-08-05 Becton, Dickinson And Company Closed-system sorting flow cytometer adapters and methods of use thereof
AU2022263229A1 (en) * 2021-04-23 2023-09-28 Becton, Dickinson And Company Fluid management system for an analyzer and/or sorter type flow type particle analyzer
US12313524B2 (en) 2021-05-14 2025-05-27 Becton, Dickinson And Company Systems for detecting light by spectral discrimination and methods for using same
US12135274B2 (en) 2021-08-10 2024-11-05 Becton, Dickinson And Company Outlet fittings for reducing bubbles at the interface with a flow cell, and flow cytometers and methods using the same
US12467845B2 (en) 2021-08-10 2025-11-11 Becton, Dickinson And Company Clamps for operably coupling an optical component to a mounting block, and methods and systems for using the same
AU2022352559A1 (en) 2021-09-21 2024-03-21 Becton, Dickinson And Company Baseline restoration circuit
IL311201A (en) 2021-11-17 2024-05-01 Becton Dickinson Co Methods for dynamic real-time adjustment of a data acquisition parameter in a flow cytometer
EP4437324A4 (en) 2021-11-24 2025-03-05 Becton, Dickinson and Company Integrated flow cytometry data quality control
CN114594040B (zh) * 2022-03-23 2025-01-03 青岛瑞斯凯尔生物科技股份有限公司 一种流式细胞仪及其工作方法
CN117054177A (zh) * 2022-05-07 2023-11-14 贝克曼库尔特生物科技（苏州）有限公司 流体系统、样本处理仪和在样本处理仪中输送流体的方法
CN119452240A (zh) * 2022-06-06 2025-02-14 贝克顿·迪金森公司 流体阻滞单元以及涉及其的流式细胞仪和方法
US20240312191A1 (en) 2023-03-14 2024-09-19 Becton, Dickinson And Company Methods for determining image filters for classifying particles of a sample and systems and methods for using same
US20240344983A1 (en) 2023-03-30 2024-10-17 Becton, Dickinson And Company Methods and systems for visualizing spectral signatures
WO2024216077A1 (en) 2023-04-13 2024-10-17 Becton, Dickinson And Company Method for categorizing molecular diagnostic signals in real time
EP4454548A1 (en) * 2023-04-25 2024-10-30 Koninklijke Philips N.V. Air flow control for hemodynamic measurement cuff
US20240377311A1 (en) 2023-05-09 2024-11-14 Becton, Dickinson And Company Methods for image-based detection and sorting and systems for same
US20240377307A1 (en) 2023-05-09 2024-11-14 Becton, Dickinson And Company Methods and systems for classifying analyte data into clusters
US20240377325A1 (en) 2023-05-09 2024-11-14 Becton, Dickinson And Company Methods for assessing cell mitochondrial morphology and systems for same
US20250085212A1 (en) 2023-09-07 2025-03-13 Becton, Dickinson And Company Integrated Optofluidic Interrogation Modules, Flow Cytometers Including the Same, and Methods of Use Thereof
US20250137905A1 (en) 2023-10-27 2025-05-01 Becton, Dickinson And Company Fluid Supply Systems Having a Flow Control Circuit and Single Fluidic Connection, and Methods of Use Thereof
US20250237657A1 (en) 2024-01-18 2025-07-24 Becton, Dickinson And Company Methods for spectrally resolving fluorophores of a sample by generalized least squares and systems for same
US20250244333A1 (en) 2024-01-31 2025-07-31 Becton, Dickinson And Company Cell viability compensation (cvc) beads for flow cytometry applications and methods of using the same
US20250297940A1 (en) 2024-03-25 2025-09-25 Becton, Dickinson And Company Methods and systems for classifying analyte data
US20250308080A1 (en) 2024-04-02 2025-10-02 Becton, Dickinson And Company Methods for label-free cell sorting and systems for same
US20250314573A1 (en) 2024-04-05 2025-10-09 Becton, Dickinson And Company Gate/population naming in flow cytometry data analysis based on geometry and data distribution
US20250314577A1 (en) 2024-04-09 2025-10-09 Becton, Dickinson And Company Methods for assessing cell nuclei morphology and systems for same
US20250321179A1 (en) 2024-04-10 2025-10-16 Becton, Dickinson And Company Quantitative flow cytometry light scatter detector alignment
US20250341455A1 (en) 2024-05-03 2025-11-06 Becton, Dickinson And Company Flow cells having an optimized flow channel geometry, flow cytometers including the same, and methods of use thereof
US20250369861A1 (en) 2024-05-31 2025-12-04 Becton, Dickinson And Company Methods and systems for singlet discrimination in flow cytometry data and systems for same
US20250377284A1 (en) 2024-06-11 2025-12-11 Becton, Dickinson And Company Flow cells having optimized high voltage electrodes, flow cytometers including the same, and methods of use thereof
WO2025257775A1 (en) 2024-06-13 2025-12-18 Nippon Becton Dickinson Company Ltd Tumor and tissue preservation reagent
US20250389636A1 (en) 2024-06-24 2025-12-25 Becton, Dickinson And Company Methods and systems for gain-independent data normalization in flow cytometry data and systems for same
US20260002864A1 (en) 2024-06-28 2026-01-01 Becton, Dickinson And Company Methods for determining positional flow stream velocity and systems for same
US20260009715A1 (en) 2024-07-03 2026-01-08 Becton, Dickinson And Company Method for flow cytometry quality scores and systems for same
US20260063530A1 (en) 2024-08-27 2026-03-05 Becton, Dickinson And Company Methods and compositions for flow cytometer calibration
US20260086018A1 (en) 2024-09-26 2026-03-26 Becton, Dickinson And Company Methods for detector gain modulation and systems for same
EP4726362A1 (en) 2024-10-09 2026-04-15 Becton Dickinson and Company Methods for monitoring flow rate of a flow stream and systems for same

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60140139A (ja) * 1983-12-27 1985-07-25 Toa Medical Electronics Co Ltd 粒子計数装置
US5395588A (en) 1992-12-14 1995-03-07 Becton Dickinson And Company Control of flow cytometer having vacuum fluidics
US5915925A (en) 1997-01-07 1999-06-29 North, Jr.; Howard L. Pulseless liquid supply system for flow cytometry
JP3608066B2 (ja) * 1997-01-14 2005-01-05 株式会社日立製作所 粒子分析装置
IL124514A (en) * 1998-05-17 2002-02-10 Davidson Chaim Method and apparatus for magnetically separating selected particles, particularly biological cells
JP2000206032A (ja) * 1999-01-06 2000-07-28 Bayer Corp 可変割合体積粒子計数装置及び試料の特性を定める方法
GB2381589B (en) * 1999-05-26 2003-09-10 Cyber Instr Technology Llc Wide range gas flow system with real time flow measurement and correction
US6119710A (en) * 1999-05-26 2000-09-19 Cyber Instrument Technologies Llc Method for wide range gas flow system with real time flow measurement and correction
JP2001050887A (ja) * 1999-08-11 2001-02-23 Sysmex Corp 粒子分析装置
US7630063B2 (en) * 2000-08-02 2009-12-08 Honeywell International Inc. Miniaturized cytometer for detecting multiple species in a sample
US6382228B1 (en) * 2000-08-02 2002-05-07 Honeywell International Inc. Fluid driving system for flow cytometry
US20020028434A1 (en) * 2000-09-06 2002-03-07 Guava Technologies, Inc. Particle or cell analyzer and method
US20030211009A1 (en) * 2001-05-18 2003-11-13 Buchanan Kris S. Rapid multi-material sample input system
US7479630B2 (en) * 2004-03-25 2009-01-20 Bandura Dmitry R Method and apparatus for flow cytometry linked with elemental analysis
AU2002318269A1 (en) * 2001-07-18 2003-03-03 The Regents Of The University Of Michigan Gas-focusing flow cytometer cell and flow cytometer detection system with waveguide optics
WO2003032101A1 (en) * 2001-10-12 2003-04-17 Fugasity Corporation System and method for making and using a mass flow device
WO2003062796A1 (en) * 2002-01-22 2003-07-31 Dakocytomation Denmark A/S Environmental containment system for a flow cytometer
US6694799B2 (en) * 2002-02-22 2004-02-24 Eastern Washington University Method and apparatus for detection of particles
US6825926B2 (en) * 2002-11-19 2004-11-30 International Remote Imaging Systems, Inc. Flow cell for urinalysis diagnostic system and method of making same
KR101166180B1 (ko) * 2003-08-13 2012-07-18 루미넥스 코포레이션 유세포 분석기식 측정 시스템의 하나 이상의 파라미터의 제어 방법
AU2004285960A1 (en) * 2003-10-30 2005-05-12 Cytonome/St, Llc Multilayer hydrodynamic sheath flow structure
AU2005290314A1 (en) * 2004-09-28 2006-04-06 Singulex, Inc. System and method for spectroscopic analysis of single particles
KR100670590B1 (ko) * 2005-10-05 2007-01-17 주식회사 디지탈바이오테크놀러지 확장된 채널을 가진 마이크로칩 및 이를 이용하는 미세입자 분석 장치
US8303894B2 (en) * 2005-10-13 2012-11-06 Accuri Cytometers, Inc. Detection and fluidic system of a flow cytometer
US8017402B2 (en) * 2006-03-08 2011-09-13 Accuri Cytometers, Inc. Fluidic system for a flow cytometer
US7776268B2 (en) 2005-10-13 2010-08-17 Accuri Cytometers, Inc. User interface for a fluidic system of a flow cytometer
US7328722B2 (en) * 2005-12-07 2008-02-12 Accuri Cytometers, Inc. Pulsation attenuator for a fluidic system
US7780916B2 (en) * 2006-03-08 2010-08-24 Accuri Cytometers, Inc. Flow cytometer system with unclogging feature
US8283177B2 (en) * 2006-03-08 2012-10-09 Accuri Cytometers, Inc. Fluidic system with washing capabilities for a flow cytometer
US8715573B2 (en) * 2006-10-13 2014-05-06 Accuri Cytometers, Inc. Fluidic system for a flow cytometer with temporal processing
WO2008058217A2 (en) * 2006-11-07 2008-05-15 Accuri Instruments Inc. Flow cell for a flow cytometer system
US7799575B2 (en) * 2006-11-07 2010-09-21 Genetix Limited Flow cytometers
US10031061B2 (en) * 2009-05-13 2018-07-24 Intellicyt Corporation Flow measurement and control for improved quantification of particles in flow cytometry
US20110061471A1 (en) * 2009-06-02 2011-03-17 Rich Collin A System and method of verification of a sample for a flow cytometer
US8507279B2 (en) * 2009-06-02 2013-08-13 Accuri Cytometers, Inc. System and method of verification of a prepared sample for a flow cytometer
US8941062B2 (en) * 2010-11-16 2015-01-27 1087 Systems, Inc. System for identifying and sorting living cells

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US8528427B2 (en) 2013-09-10
WO2012058142A1 (en) 2012-05-03
AU2011320713B2 (en) 2014-06-26
US9092034B2 (en) 2015-07-28
US20140158212A1 (en) 2014-06-12
ES2732355T3 (es) 2019-11-22
US20120103112A1 (en) 2012-05-03
EP2633283B1 (en) 2019-05-01
CN103201611A (zh) 2013-07-10
SG189532A1 (en) 2013-05-31
ZA201302955B (en) 2014-10-29
JP2014503792A (ja) 2014-02-13
CN103201611B (zh) 2015-03-11
EP2633283A1 (en) 2013-09-04

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