JP5763525B2 - 粒子からの核酸複合体の送達 - Google Patents

粒子からの核酸複合体の送達 Download PDF

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JP5763525B2
JP5763525B2 JP2011508670A JP2011508670A JP5763525B2 JP 5763525 B2 JP5763525 B2 JP 5763525B2 JP 2011508670 A JP2011508670 A JP 2011508670A JP 2011508670 A JP2011508670 A JP 2011508670A JP 5763525 B2 JP5763525 B2 JP 5763525B2
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nucleic acid
particles
polymer
solution
acid complex
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JP2011520813A (ja
JP2011520813A5 (OSRAM
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スラヘル,ヨラム
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サーモディクス,インコーポレイティド
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    • AHUMAN NECESSITIES
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    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
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    • A61K47/6921Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
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JP2011508670A 2008-05-07 2009-05-07 粒子からの核酸複合体の送達 Expired - Fee Related JP5763525B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5104108P 2008-05-07 2008-05-07
US61/051,041 2008-05-07
PCT/US2009/043158 WO2009137689A2 (en) 2008-05-07 2009-05-07 Delivery of nucleic acid complexes from particles

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JP2011520813A JP2011520813A (ja) 2011-07-21
JP2011520813A5 JP2011520813A5 (OSRAM) 2012-06-28
JP5763525B2 true JP5763525B2 (ja) 2015-08-12

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US (1) US8936811B2 (OSRAM)
EP (1) EP2296630A2 (OSRAM)
JP (1) JP5763525B2 (OSRAM)
CA (1) CA2723192A1 (OSRAM)
WO (1) WO2009137689A2 (OSRAM)

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CA2931547A1 (en) 2013-12-09 2015-06-18 Durect Corporation Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same
JP6557935B2 (ja) 2014-11-18 2019-08-14 国立研究開発法人物質・材料研究機構 多孔性粒子の製造方法
CN108366964B (zh) * 2015-12-18 2022-04-08 三养控股公司 制备含阴离子药物的聚合物胶束的方法
KR101882133B1 (ko) * 2017-02-21 2018-07-25 성균관대학교산학협력단 핵산과 결합 가능한 펩타이드를 이용하여 핵산을 분리하는 방법
US11590080B2 (en) 2017-12-18 2023-02-28 C.R. Bard, Inc. Drug-loaded biodegradable microbead compositions including drug-containing vesicular agents
AU2018390560B2 (en) * 2017-12-18 2024-09-19 C. R. Bard, Inc. Drug-loaded microbead compositions, embolization compositions and associated methods
WO2021072385A1 (en) * 2019-10-10 2021-04-15 University Of Maryland, Baltimore Compositions and methods for delivering nucleic acids to cells
US20220313616A1 (en) * 2021-03-30 2022-10-06 Celanese Eva Performance Polymers Llc Implantable Medical Device for the Delivery of Nucleic Acid-Encapsulated Particles
CN118879783B (zh) * 2024-07-04 2025-08-08 恒敬合创生物医药(浙江)有限公司 一种用于包裹核酸药物的环状脂肽载体

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