JP5756961B2 - オキシントモジュリン類似体 - Google Patents

オキシントモジュリン類似体 Download PDF

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Publication number
JP5756961B2
JP5756961B2 JP2011551052A JP2011551052A JP5756961B2 JP 5756961 B2 JP5756961 B2 JP 5756961B2 JP 2011551052 A JP2011551052 A JP 2011551052A JP 2011551052 A JP2011551052 A JP 2011551052A JP 5756961 B2 JP5756961 B2 JP 5756961B2
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JP
Japan
Prior art keywords
peptide
seq
acid
residue
amino
Prior art date
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Expired - Fee Related
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JP2011551052A
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English (en)
Japanese (ja)
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JP2012518035A (ja
JP2012518035A5 (Direct
Inventor
イー． キャリントン，ポール
イー． キャリントン，ポール
ジェイ． エイエルマン，ジョージ
ジェイ． エイエルマン，ジョージ
ジェイ． マーシュ，ドナルド
ジェイ． マーシュ，ドナルド
エム． メッツガー，ジョセフ
エム． メッツガー，ジョセフ
ポカイ，アレスサンドロ
ロイ，ラナビール シンハ
ロイ，ラナビール シンハ
ビアンチ，エリサベッタ
インガリネッラ，パオロ
ペッシ，アントネッロ
サントプレテ，アレッシア
カピト，エレナ
ディマルチィ，リチャード
ワード，ブリアン
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Istituto di Ricerche di Biologia Molecolare P Angeletti SpA
Indiana University Research and Technology Corp
Original Assignee
Istituto di Ricerche di Biologia Molecolare P Angeletti SpA
Indiana University Research and Technology Corp
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Publication of JP2012518035A publication Critical patent/JP2012518035A/ja
Publication of JP2012518035A5 publication Critical patent/JP2012518035A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Physical Water Treatments (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2011551052A 2009-02-19 2009-12-18 オキシントモジュリン類似体 Expired - Fee Related JP5756961B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
USPCT/US2009/034448 2009-02-19
PCT/US2009/034448 WO2010096052A1 (en) 2009-02-19 2009-02-19 Oxyntomodulin analogs
PCT/US2009/068678 WO2010096142A1 (en) 2009-02-19 2009-12-18 Oxyntomodulin analogs

Publications (3)

Publication Number Publication Date
JP2012518035A JP2012518035A (ja) 2012-08-09
JP2012518035A5 JP2012518035A5 (Direct) 2013-02-07
JP5756961B2 true JP5756961B2 (ja) 2015-07-29

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JP2011551052A Expired - Fee Related JP5756961B2 (ja) 2009-02-19 2009-12-18 オキシントモジュリン類似体

Country Status (23)

Country Link
US (2) US20120165503A1 (Direct)
EP (1) EP2398483B1 (Direct)
JP (1) JP5756961B2 (Direct)
KR (1) KR101634139B1 (Direct)
CN (1) CN102573872B (Direct)
AU (1) AU2009340439B2 (Direct)
BR (1) BRPI0924307B8 (Direct)
CA (1) CA2754350C (Direct)
CL (1) CL2011002036A1 (Direct)
CY (1) CY1116917T1 (Direct)
DK (1) DK2398483T3 (Direct)
ES (1) ES2524477T3 (Direct)
HR (1) HRP20141215T1 (Direct)
IL (1) IL214729A (Direct)
MX (1) MX2011008717A (Direct)
PE (1) PE20120621A1 (Direct)
PL (1) PL2398483T3 (Direct)
PT (1) PT2398483E (Direct)
RU (1) RU2542362C2 (Direct)
SG (1) SG173791A1 (Direct)
SI (1) SI2398483T1 (Direct)
WO (2) WO2010096052A1 (Direct)
ZA (1) ZA201106051B (Direct)

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* Cited by examiner, † Cited by third party
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