JP5726070B2 - 流体注入ボーラスの患者へ送達及び有害流体を取り扱う装置及び方法 - Google Patents
流体注入ボーラスの患者へ送達及び有害流体を取り扱う装置及び方法 Download PDFInfo
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- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1007—Arrangements or means for the introduction of sources into the body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/007—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests for contrast media
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/16804—Flow controllers
- A61M5/16827—Flow controllers controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/1785—Syringes comprising radioactive shield means
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M2005/1401—Functional features
- A61M2005/1402—Priming
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/02—Gases
- A61M2202/0225—Carbon oxides, e.g. Carbon dioxide
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0468—Liquids non-physiological
- A61M2202/049—Toxic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/11—Laminar flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/18—Coaxial flows, e.g. one flow within another
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/0318—Processes
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- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Description
本願は、2009年4月21日に出願された米国特許出願第61/171,240号、発明の名称“Apparatus and Methods for Delivery of Fluid Injection Boluses to Patients and Handling Harmful Fluids”、2009年2月17日に出願された米国特許出願第61/153,070号、発明の名称“Apparatus and Methods for Delivery of Fluid Injection Boluses to Patients and Handling Harmful Fluids”及び2008年6月6日に出願された米国特許出願第61/059,384号、発明の名称“Apparatus and Methods for Delivery of Fluid Injection Boluses to Patients”の利益を主張する。
この出願は、引用を以て、2007年12月28日に出願されたPCT/US07/89101(WO 2008/083313)、発明の名称“Methods and Systems for Integrated Radiopharmaceutical Generation, Preparation, Transportation, and Administration”が組み込まれるものとし、前記PCT/US07/89101は、2007年4月9日に出願された米国仮特許出願第60/910,810号、発明の名称“Methods and Systems for Integrated Radiopharmaceutical Generation, Preparation”、2007年1月1日に出願された米国仮特許出願第60/878,334号、発明の名称“Methods and Equipment for Handling Radiopharmaceuticals”及び" と、2007年1月1日に出願された米国仮特許出願第60/878,333号の利益を主張する。
身体の内部構造(骨、血管、臓器、臓器系及び他の組織などが挙げられるが、それらに限定されるものではない)及び/又は機能の情報又は像を提供するために、医薬分野では、放射性薬剤と一般的に呼ばれる放射性医薬用物質又は薬剤を投与することがしばしば行われている。さらに、放射性薬剤は、癌細胞等の標的細胞又は標的組織の成長を停止又は阻害するための治療薬としても使われる。しかしながら、イメージング処理及び治療処理で使用される放射性薬剤は、典型的には、半減期が短い高度に放射性の核種を含んでおり、医療従事者に有害である。医療従事者(例えば臨床医、画像技術者、看護婦及び薬剤師)は放射性薬剤に繰り返し曝されるので、放射性薬剤は、これらの者に対して、有毒であり、肉体的及び又は化学的影響を及ぼす可能性がある。しかしながら、個々の患者に対しては、典型的な放射性薬剤は半減期が短く、曝露が少量であるので、放射能曝露の危険性があっても、利点の方が受け入れられる。しかしながら、医療従事者の場合、長期間に亘って放射性薬剤からの放射能を絶えず繰り返し受けるため、核医学分野における深刻な問題である。
Claims (8)
- 有害流体を送達するシステムであって、
ハウジングと、
ハウジング内に配備され、シールドされた囲いを形成する1又は複数のシールド要素と、
シールドされた囲いの中に配備された第1流体経路要素と、
ハウジング内に配備され、第1流体経路要素と流体接続された第2流体経路要素と、
第1流体経路要素及び第2流体経路要素と流体接続された第3流体経路要素と、
第1流体経路要素及び第3流体経路要素の一方又は複数の流体経路要素と制御可能に流体接続され、第1流体経路要素及び第3流体経路要素の一方又は複数の流体経路要素から流体を分配するように構成されたポンプユニットとを具えている有害流体送達システム。 - 第1流体経路要素及び第2流体経路要素のうちの少なくとも1つは、ハウジングから外側に向けられるコイル状チュービングを具えている、請求項1に記載の有害流体送達システム。
- 第1流体経路要素及び第2流体経路要素のうちの少なくとも1つに連繋された流体検出器をさらに具えている、請求項1に記載の有害流体送達システム。
- 流体検出器は、放射線検出器及び空気検出器のうちの少なくとも1つを具えている、請求項3に記載の有害流体送達システム。
- 放射性薬剤のコンパクトボーラスを患者に送達するために放射性薬剤送達システムをプライミングする方法であって、
第1液体を流体経路要素に送給し、
流体セパレータを流体経路要素に送給し、
放射性薬剤を流体経路要素に送給することを含んでおり、第1液体と放射性薬剤は流体セパレータによって分離される、方法。 - 層流注入ボーラスにおける有害流体の拡がりを軽減する方法であって、
第1流体を第1ルーメンを通って流体流れ経路に注入し、
第2流体を、第1ルーメンの周りに同心に配備された第2ルーメンを通って流体流れ経路に注入することを含んでおり、
第1流体は、流体流れ経路内の層流の略中心部を移動し、第2流体は、流体流れ経路内の第1流体の周りを略同心状に移動するようになし、
第1ルーメン下流の流体経路の層流の中心部から、軸心にある出口ルーメンを通って第1流体を取り除くことを含んでいる、方法。 - 有害流体を充填及び輸送するシステムであって、有害流体輸送容器と充填システムとを具えており、
前記流体輸送容器は、
ハウジングと、
ハウジングの中に配備された第1流体経路要素と、
各々がハウジング内に配備され、第1流体経路要素を取り囲む囲いを形成する1又は複数のシールド要素と、
ハウジング内に配備され、第1流体経路要素に流体接続された第2流体経路要素と、
第1流体経路要素及び第2流体経路要素と流体接続された第3流体経路要素と、を具えており、
前記充填システムは、少なくとも第1流体経路要素に可逆的に流体接続された少なくとも第1流体源と、少なくとも第2流体経路要素に可逆的に流体接続された第2流体源とを有し、第1流体源、第2流体源の1又は複数の流体源に連繋され、第1流体源及び第2流体源からの流体を第1流体経路要素及び第2流体経路要素に分配する少なくとも1つの流体ポンプをさらに具えている、有害流体充填及び輸送システム。 - 有害流体を輸送する容器であって、
ハウジングと、
ハウジングの中に配備された第1流体経路要素と、
各々がハウジング内に配備され、第1流体経路要素を取り囲む囲いを形成する1又は複数のシールド要素と、
ハウジング内に配備され、第1流体経路要素に流体接続された第2流体経路要素と、
第1流体経路要素及び第2流体経路要素と流体接続された第3流体経路要素と、を具えており、
流体経路要素の少なくとも1つは、ハウジングの外側からアクセスされることができるよう構成される、有害流体輸送容器。
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5938408P | 2008-06-06 | 2008-06-06 | |
US61/059,384 | 2008-06-06 | ||
US15307009P | 2009-02-17 | 2009-02-17 | |
US61/153,070 | 2009-02-17 | ||
US17124009P | 2009-04-21 | 2009-04-21 | |
US61/171,240 | 2009-04-21 | ||
PCT/US2009/046437 WO2009149367A1 (en) | 2008-06-06 | 2009-06-05 | Apparatus and methods for delivery of fluid injection boluses to patients and handling harmful fluids |
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JP2015071170A Division JP6325480B2 (ja) | 2008-06-06 | 2015-03-31 | 流体注入ボーラスを患者に送達するための装置及び方法並びに有害流体を取り扱うための装置及び方法 |
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JP2011522623A JP2011522623A (ja) | 2011-08-04 |
JP2011522623A5 JP2011522623A5 (ja) | 2012-07-19 |
JP5726070B2 true JP5726070B2 (ja) | 2015-05-27 |
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JP2011512697A Expired - Fee Related JP5726070B2 (ja) | 2008-06-06 | 2009-06-05 | 流体注入ボーラスの患者へ送達及び有害流体を取り扱う装置及び方法 |
JP2015071170A Active JP6325480B2 (ja) | 2008-06-06 | 2015-03-31 | 流体注入ボーラスを患者に送達するための装置及び方法並びに有害流体を取り扱うための装置及び方法 |
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US (2) | US9056200B2 (ja) |
EP (1) | EP2315883A4 (ja) |
JP (2) | JP5726070B2 (ja) |
CN (2) | CN104587552B (ja) |
HK (1) | HK1210067A1 (ja) |
WO (1) | WO2009149367A1 (ja) |
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-
2009
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- 2009-06-05 JP JP2011512697A patent/JP5726070B2/ja not_active Expired - Fee Related
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US9056200B2 (en) | 2015-06-16 |
EP2315883A1 (en) | 2011-05-04 |
HK1210067A1 (en) | 2016-04-15 |
CN104587552B (zh) | 2017-11-14 |
CN102119252B (zh) | 2015-02-18 |
JP2011522623A (ja) | 2011-08-04 |
US20140046295A1 (en) | 2014-02-13 |
WO2009149367A1 (en) | 2009-12-10 |
JP6325480B2 (ja) | 2018-05-16 |
US20110209764A1 (en) | 2011-09-01 |
US9750953B2 (en) | 2017-09-05 |
EP2315883A4 (en) | 2014-07-09 |
CN102119252A (zh) | 2011-07-06 |
JP2015165893A (ja) | 2015-09-24 |
CN104587552A (zh) | 2015-05-06 |
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