JP5710268B2 - ８−アニリノイミダゾピリジン及びその抗ガン及び／又は抗炎症剤としての使用 - Google Patents

８−アニリノイミダゾピリジン及びその抗ガン及び／又は抗炎症剤としての使用 Download PDF

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JP5710268B2
JP5710268B2 JP2010539814A JP2010539814A JP5710268B2 JP 5710268 B2 JP5710268 B2 JP 5710268B2 JP 2010539814 A JP2010539814 A JP 2010539814A JP 2010539814 A JP2010539814 A JP 2010539814A JP 5710268 B2 JP5710268 B2 JP 5710268B2
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alkyl
compound
formula
imidazo
pyridine
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JP2011507888A5 (enExample
JP2011507888A (ja
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スティーヴン プライス，
スティーヴン プライス，
ロバート ヒールド，
ロバート ヒールド，
パスカル ピエール アレクサンドル サヴィ，
パスカル ピエール アレクサンドル サヴィ，
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Genentech Inc
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Genentech Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
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    • A61P17/00—Drugs for dermatological disorders
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    • A61P19/00—Drugs for skeletal disorders
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    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
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    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
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    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Biomedical Technology (AREA)
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  • Oncology (AREA)
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  • Urology & Nephrology (AREA)
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  • Ophthalmology & Optometry (AREA)
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JP2010539814A 2007-12-19 2008-12-18 ８−アニリノイミダゾピリジン及びその抗ガン及び／又は抗炎症剤としての使用 Expired - Fee Related JP5710268B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US1515507P 2007-12-19 2007-12-19
US61/015,155 2007-12-19
US5402408P 2008-05-16 2008-05-16
US61/054,024 2008-05-16
PCT/US2008/087476 WO2009085980A1 (en) 2007-12-19 2008-12-18 8-anilin0imidaz0pyridines and their use as anti-cancer and/or anti-inflammatory agents

Publications (3)

Publication Number Publication Date
JP2011507888A JP2011507888A (ja) 2011-03-10
JP2011507888A5 JP2011507888A5 (enExample) 2012-02-23
JP5710268B2 true JP5710268B2 (ja) 2015-04-30

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JP2010539814A Expired - Fee Related JP5710268B2 (ja) 2007-12-19 2008-12-18 ８−アニリノイミダゾピリジン及びその抗ガン及び／又は抗炎症剤としての使用

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Country Link
US (1) US8293763B2 (enExample)
EP (1) EP2231662B1 (enExample)
JP (1) JP5710268B2 (enExample)
KR (1) KR20100101666A (enExample)
CN (1) CN101903387B (enExample)
AT (1) ATE513832T1 (enExample)
AU (1) AU2008343062B2 (enExample)
CA (1) CA2704125A1 (enExample)
DK (1) DK2231662T3 (enExample)
IL (1) IL205490A (enExample)
NZ (1) NZ585306A (enExample)
PL (1) PL2231662T3 (enExample)
PT (1) PT2231662E (enExample)
RU (1) RU2498985C2 (enExample)
WO (1) WO2009085980A1 (enExample)
ZA (1) ZA201003046B (enExample)

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RU2010129910A (ru) 2012-01-27
CA2704125A1 (en) 2009-07-09
ATE513832T1 (de) 2011-07-15
AU2008343062A1 (en) 2009-07-09
IL205490A0 (en) 2010-12-30
EP2231662A1 (en) 2010-09-29
NZ585306A (en) 2012-05-25
KR20100101666A (ko) 2010-09-17
CN101903387B (zh) 2014-05-21
PT2231662E (pt) 2011-09-12
US8293763B2 (en) 2012-10-23
PL2231662T3 (pl) 2011-11-30
US20100280063A1 (en) 2010-11-04
RU2498985C2 (ru) 2013-11-20
CN101903387A (zh) 2010-12-01
JP2011507888A (ja) 2011-03-10
EP2231662B1 (en) 2011-06-22
AU2008343062B2 (en) 2013-03-07
ZA201003046B (en) 2011-08-31
DK2231662T3 (da) 2011-08-29

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