JP5680964B2 - 自閉症スペクトラム障害のためのバイオマーカー - Google Patents

自閉症スペクトラム障害のためのバイオマーカー Download PDF

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JP5680964B2
JP5680964B2 JP2010527310A JP2010527310A JP5680964B2 JP 5680964 B2 JP5680964 B2 JP 5680964B2 JP 2010527310 A JP2010527310 A JP 2010527310A JP 2010527310 A JP2010527310 A JP 2010527310A JP 5680964 B2 JP5680964 B2 JP 5680964B2
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asd
ptchd1
cnv
gene
mutation
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JP2010539958A (ja
JP2010539958A5 (enExample
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ダブリュ．シェーラー スティーブン
ダブリュ．シェーラー スティーブン
ビー．ビンセント ジョン
ビー．ビンセント ジョン
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Hospital for Sick Children HSC
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2010527310A 2007-10-04 2008-10-03 自閉症スペクトラム障害のためのバイオマーカー Active JP5680964B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US96057207P 2007-10-04 2007-10-04
US60/960,572 2007-10-04
US829407P 2007-12-20 2007-12-20
US61/008,294 2007-12-20
PCT/CA2008/001767 WO2009043178A1 (en) 2007-10-04 2008-10-03 Biomarkers for autism spectrum disorders

Related Child Applications (1)

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JP2014116245A Division JP5941099B2 (ja) 2007-10-04 2014-06-04 自閉症スペクトラム障害のためのバイオマーカー

Publications (3)

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JP2010539958A JP2010539958A (ja) 2010-12-24
JP2010539958A5 JP2010539958A5 (enExample) 2013-12-26
JP5680964B2 true JP5680964B2 (ja) 2015-03-04

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JP2010527310A Active JP5680964B2 (ja) 2007-10-04 2008-10-03 自閉症スペクトラム障害のためのバイオマーカー
JP2014116245A Active JP5941099B2 (ja) 2007-10-04 2014-06-04 自閉症スペクトラム障害のためのバイオマーカー

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US (4) US20100248235A1 (enExample)
JP (2) JP5680964B2 (enExample)
CA (1) CA2701202C (enExample)
WO (1) WO2009043178A1 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10522240B2 (en) 2006-05-03 2019-12-31 Population Bio, Inc. Evaluating genetic disorders
US7702468B2 (en) 2006-05-03 2010-04-20 Population Diagnostics, Inc. Evaluating genetic disorders
JP5680964B2 (ja) 2007-10-04 2015-03-04 ザ ホスピタル フォー シック チルドレン 自閉症スペクトラム障害のためのバイオマーカー
WO2011031786A2 (en) * 2009-09-08 2011-03-17 Laboratory Corporation Of America Holdings Compositions and methods for diagnosing autism spectrum disorders
US9547013B2 (en) * 2010-04-29 2017-01-17 Wisconsin Alumni Research Foundation Molecule biomarkers of autism
WO2012018387A2 (en) 2010-08-02 2012-02-09 Population Diagnotics, Inc. Compositions and methods for discovery of causative mutations in genetic disorders
CA2744424A1 (en) * 2010-09-14 2012-03-14 The Hospital For Sick Children Biomarkers for autism spectrum disorders
WO2012173809A2 (en) * 2011-06-02 2012-12-20 Ehli Erik Method of identifying de novo copy number variants (cnv) using mz twins discordant for attention problems/disorders
CA2851388C (en) * 2011-10-10 2023-11-21 The Hospital For Sick Children Methods and compositions for screening and treating developmental disorders
US11180807B2 (en) 2011-11-04 2021-11-23 Population Bio, Inc. Methods for detecting a genetic variation in attractin-like 1 (ATRNL1) gene in subject with Parkinson's disease
EP2812452B1 (en) 2012-02-09 2020-05-27 Population Bio, Inc. Methods and compositions for screening and treating developmental disorders
JP2015510756A (ja) * 2012-03-09 2015-04-13 アンテグラージェン 自閉症のリスクを評価するため遺伝子型決定テスト
US9976180B2 (en) 2012-09-14 2018-05-22 Population Bio, Inc. Methods for detecting a genetic variation in subjects with parkinsonism
WO2014052855A1 (en) 2012-09-27 2014-04-03 Population Diagnostics, Inc. Methods and compositions for screening and treating developmental disorders
CA2996445A1 (en) 2014-09-05 2016-03-10 Eli Hatchwell Methods and compositions for inhibiting and treating neurological conditions
WO2016109449A1 (en) * 2014-12-29 2016-07-07 The Board Of Trustees Of The Leland Stanford Junior University Methods of diagnosing autism spectrum disorders
US10240205B2 (en) 2017-02-03 2019-03-26 Population Bio, Inc. Methods for assessing risk of developing a viral disease using a genetic test
WO2018183525A1 (en) * 2017-03-28 2018-10-04 The Regents Of The University Of California Methods for assessing risk of or diagnosing genetic defects by identifying de novo mutations or somatic mosaic variants in sperm or somatic tissues
FI4417708T3 (fi) 2018-08-08 2025-12-04 Pml Screening Llc Menetelmiä virustaudin kehittymisen riskin arvioimiseksi geneettisen testin avulla
CN111575366A (zh) * 2020-05-22 2020-08-25 深圳市亿立方生物技术有限公司 用于检测自闭症基因组拷贝数变异的引物组、探针组及试剂盒
CN113528650B (zh) * 2021-08-03 2022-03-08 长沙艾克曼生物科技有限公司 Tmp21基因的表达可以作为自闭症早期筛查、早期识别和症状严重程度预测的客观指标
EP4148147A1 (en) * 2021-09-10 2023-03-15 Universitätsmedizin der Johannes Gutenberg-Universität Mainz Means and method for the diagnosis and treatment of autism spectrum disorders based on the detection and modulation of a deubiquitinase
CN117025758B (zh) * 2023-09-19 2024-04-05 华北理工大学 环状rna在制备诊断孤独症的生物标志物中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US173495A (en) * 1876-02-15 Improvement in seed-sowers
CA2571370A1 (en) * 2004-07-01 2006-01-12 Integragen Human autism susceptibility gene encoding prkcb1 and uses thereof
JP5680964B2 (ja) 2007-10-04 2015-03-04 ザ ホスピタル フォー シック チルドレン 自閉症スペクトラム障害のためのバイオマーカー

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Publication number Publication date
JP2014155507A (ja) 2014-08-28
US20200157628A1 (en) 2020-05-21
US10526653B2 (en) 2020-01-07
JP2010539958A (ja) 2010-12-24
WO2009043178A1 (en) 2009-04-09
JP5941099B2 (ja) 2016-06-29
US20150322518A1 (en) 2015-11-12
US12467093B2 (en) 2025-11-11
US11254984B2 (en) 2022-02-22
CA2701202A1 (en) 2009-04-09
CA2701202C (en) 2018-01-02
US20220136055A1 (en) 2022-05-05
US20100248235A1 (en) 2010-09-30

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