JP5656634B2 - タンパク質チロシンキナーゼ活性の阻害剤 - Google Patents

タンパク質チロシンキナーゼ活性の阻害剤 Download PDF

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JP5656634B2
JP5656634B2 JP2010522149A JP2010522149A JP5656634B2 JP 5656634 B2 JP5656634 B2 JP 5656634B2 JP 2010522149 A JP2010522149 A JP 2010522149A JP 2010522149 A JP2010522149 A JP 2010522149A JP 5656634 B2 JP5656634 B2 JP 5656634B2
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JP2010536887A5 (enExample
JP2010536887A (ja
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ウィリアム クラリッジ,ステファン
ウィリアム クラリッジ,ステファン
イサコヴィック,リュボミール
マニオン,マイケル
ラエペル,ステファン
マリオ サーヴェドラ,オスカー
マリオ サーヴェドラ,オスカー
ゴーデット,フレデリック
ジャン,リジエ
ゼット. ジョウ,ナンシー
ゼット. ジョウ,ナンシー
ラエペル,フランク
デジール,ロベール
ヴァイスバーグ,アルカディー
哲之 宇野
哲之 宇野
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メチルジーン インコーポレイテッド
メチルジーン インコーポレイテッド
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
JP2010522149A 2007-08-29 2008-08-28 タンパク質チロシンキナーゼ活性の阻害剤 Active JP5656634B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96867307P 2007-08-29 2007-08-29
US60/968,673 2007-08-29
PCT/CA2008/001538 WO2009026717A1 (en) 2007-08-29 2008-08-28 Inhibitors of protein tyrosine kinase activity

Publications (3)

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JP2010536887A JP2010536887A (ja) 2010-12-02
JP2010536887A5 JP2010536887A5 (enExample) 2011-10-13
JP5656634B2 true JP5656634B2 (ja) 2015-01-21

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JP2010522149A Active JP5656634B2 (ja) 2007-08-29 2008-08-28 タンパク質チロシンキナーゼ活性の阻害剤

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US (3) US8404846B2 (enExample)
EP (1) EP2183254B1 (enExample)
JP (1) JP5656634B2 (enExample)
KR (1) KR101556269B1 (enExample)
CN (3) CN109970759A (enExample)
AR (1) AR068066A1 (enExample)
AU (1) AU2008293038B2 (enExample)
BR (1) BRPI0816064B8 (enExample)
CA (1) CA2697795C (enExample)
DK (1) DK2183254T3 (enExample)
ES (1) ES2635131T3 (enExample)
IL (1) IL204192A (enExample)
MX (1) MX2010002427A (enExample)
MY (1) MY156536A (enExample)
PL (1) PL2183254T3 (enExample)
RU (1) RU2495044C2 (enExample)
TW (1) TWI571468B (enExample)
WO (1) WO2009026717A1 (enExample)
ZA (1) ZA201001512B (enExample)

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CN110913842A (zh) 2017-07-19 2020-03-24 伊尼塔公司 包括恩曲替尼的药物组合物
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CN109384799B (zh) * 2018-11-12 2020-07-14 深圳海王医药科技研究院有限公司 一种多靶点激酶抑制剂化合物的晶型a及制备方法和含有其的药物组合物
KR20220059386A (ko) 2019-09-06 2022-05-10 웰마커바이오 주식회사 바이오마커 기반 치료용 조성물
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Also Published As

Publication number Publication date
PL2183254T3 (pl) 2017-10-31
US20090264440A1 (en) 2009-10-22
EP2183254B1 (en) 2017-06-21
CN105777776A (zh) 2016-07-20
ES2635131T3 (es) 2017-10-02
US8389541B2 (en) 2013-03-05
RU2010111729A (ru) 2011-10-10
BRPI0816064B1 (pt) 2020-01-28
US20130165477A1 (en) 2013-06-27
CN101932586A (zh) 2010-12-29
DK2183254T3 (en) 2017-09-11
EP2183254A4 (en) 2011-09-28
TWI571468B (zh) 2017-02-21
AU2008293038A1 (en) 2009-03-05
US20120108628A1 (en) 2012-05-03
US8846927B2 (en) 2014-09-30
WO2009026717A1 (en) 2009-03-05
MY156536A (en) 2016-02-26
TW200914458A (en) 2009-04-01
AR068066A1 (es) 2009-11-04
BRPI0816064B8 (pt) 2021-05-25
BRPI0816064A2 (pt) 2015-03-31
ZA201001512B (en) 2010-11-24
CA2697795A1 (en) 2009-03-05
CN109970759A (zh) 2019-07-05
CN105777776B (zh) 2021-06-08
KR101556269B1 (ko) 2015-09-30
JP2010536887A (ja) 2010-12-02
US8404846B2 (en) 2013-03-26
RU2495044C2 (ru) 2013-10-10
AU2008293038B2 (en) 2013-08-29
MX2010002427A (es) 2010-03-30
CA2697795C (en) 2016-08-16
EP2183254A1 (en) 2010-05-12
IL204192A (en) 2016-08-31
KR20100075873A (ko) 2010-07-05

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