JP5656634B2 - タンパク質チロシンキナーゼ活性の阻害剤 - Google Patents

タンパク質チロシンキナーゼ活性の阻害剤 Download PDF

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Publication number
JP5656634B2
JP5656634B2 JP2010522149A JP2010522149A JP5656634B2 JP 5656634 B2 JP5656634 B2 JP 5656634B2 JP 2010522149 A JP2010522149 A JP 2010522149A JP 2010522149 A JP2010522149 A JP 2010522149A JP 5656634 B2 JP5656634 B2 JP 5656634B2
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JP2010536887A (ja
JP2010536887A5 (enExample
Inventor
ウィリアム クラリッジ，ステファン
ウィリアム クラリッジ，ステファン
イサコヴィック，リュボミール
マニオン，マイケル
ラエペル，ステファン
マリオ サーヴェドラ，オスカー
マリオ サーヴェドラ，オスカー
ゴーデット，フレデリック
ジャン，リジエ
ゼット． ジョウ，ナンシー
ゼット． ジョウ，ナンシー
ラエペル，フランク
デジール，ロベール
ヴァイスバーグ，アルカディー
哲之 宇野
哲之 宇野
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メチルジーン インコーポレイテッド
メチルジーン インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2010522149A 2007-08-29 2008-08-28 タンパク質チロシンキナーゼ活性の阻害剤 Active JP5656634B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96867307P 2007-08-29 2007-08-29
US60/968,673 2007-08-29
PCT/CA2008/001538 WO2009026717A1 (en) 2007-08-29 2008-08-28 Inhibitors of protein tyrosine kinase activity

Publications (3)

Publication Number Publication Date
JP2010536887A JP2010536887A (ja) 2010-12-02
JP2010536887A5 JP2010536887A5 (enExample) 2011-10-13
JP5656634B2 true JP5656634B2 (ja) 2015-01-21

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JP2010522149A Active JP5656634B2 (ja) 2007-08-29 2008-08-28 タンパク質チロシンキナーゼ活性の阻害剤

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US (3) US8404846B2 (enExample)
EP (1) EP2183254B1 (enExample)
JP (1) JP5656634B2 (enExample)
KR (1) KR101556269B1 (enExample)
CN (3) CN101932586A (enExample)
AR (1) AR068066A1 (enExample)
AU (1) AU2008293038B2 (enExample)
BR (1) BRPI0816064B8 (enExample)
CA (1) CA2697795C (enExample)
DK (1) DK2183254T3 (enExample)
ES (1) ES2635131T3 (enExample)
IL (1) IL204192A (enExample)
MX (1) MX2010002427A (enExample)
MY (1) MY156536A (enExample)
PL (1) PL2183254T3 (enExample)
RU (1) RU2495044C2 (enExample)
TW (1) TWI571468B (enExample)
WO (1) WO2009026717A1 (enExample)
ZA (1) ZA201001512B (enExample)

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CN109384799B (zh) * 2018-11-12 2020-07-14 深圳海王医药科技研究院有限公司 一种多靶点激酶抑制剂化合物的晶型a及制备方法和含有其的药物组合物
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Also Published As

Publication number Publication date
DK2183254T3 (en) 2017-09-11
EP2183254B1 (en) 2017-06-21
EP2183254A1 (en) 2010-05-12
EP2183254A4 (en) 2011-09-28
AR068066A1 (es) 2009-11-04
US20130165477A1 (en) 2013-06-27
TWI571468B (zh) 2017-02-21
CA2697795A1 (en) 2009-03-05
AU2008293038A1 (en) 2009-03-05
JP2010536887A (ja) 2010-12-02
ES2635131T3 (es) 2017-10-02
AU2008293038B2 (en) 2013-08-29
MX2010002427A (es) 2010-03-30
WO2009026717A1 (en) 2009-03-05
BRPI0816064A2 (pt) 2015-03-31
US20090264440A1 (en) 2009-10-22
US8846927B2 (en) 2014-09-30
CA2697795C (en) 2016-08-16
TW200914458A (en) 2009-04-01
CN105777776A (zh) 2016-07-20
CN101932586A (zh) 2010-12-29
RU2495044C2 (ru) 2013-10-10
CN105777776B (zh) 2021-06-08
US20120108628A1 (en) 2012-05-03
MY156536A (en) 2016-02-26
US8389541B2 (en) 2013-03-05
RU2010111729A (ru) 2011-10-10
CN109970759A (zh) 2019-07-05
KR101556269B1 (ko) 2015-09-30
BRPI0816064B1 (pt) 2020-01-28
IL204192A (en) 2016-08-31
KR20100075873A (ko) 2010-07-05
BRPI0816064B8 (pt) 2021-05-25
ZA201001512B (en) 2010-11-24
US8404846B2 (en) 2013-03-26
PL2183254T3 (pl) 2017-10-31

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