JP5647098B2 - オピオイド拮抗薬とｍＴＯＲ阻害薬を用いた治療 - Google Patents

オピオイド拮抗薬とｍＴＯＲ阻害薬を用いた治療 Download PDF

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JP5647098B2
JP5647098B2 JP2011500985A JP2011500985A JP5647098B2 JP 5647098 B2 JP5647098 B2 JP 5647098B2 JP 2011500985 A JP2011500985 A JP 2011500985A JP 2011500985 A JP2011500985 A JP 2011500985A JP 5647098 B2 JP5647098 B2 JP 5647098B2
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opioid receptor
receptor antagonist
mtor
methylnaltrexone
mtor inhibitor
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JP2011515415A5 (enExample
JP2011515415A (ja
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ジョナサン モス
ジョナサン モス
パトリック エイ シングルトン
パトリック エイ シングルトン
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ザ ユニヴァーシティー オヴ シカゴ
ザ ユニヴァーシティー オヴ シカゴ
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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JP2011500985A 2008-03-21 2009-03-20 オピオイド拮抗薬とｍＴＯＲ阻害薬を用いた治療 Active JP5647098B2 (ja)

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US3857708P 2008-03-21 2008-03-21
US61/038,577 2008-03-21
PCT/US2009/037825 WO2009117669A2 (en) 2008-03-21 2009-03-20 Treatment with opioid antagonists and mtor inhibitors

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JP2011515415A JP2011515415A (ja) 2011-05-19
JP2011515415A5 JP2011515415A5 (enExample) 2012-05-17
JP5647098B2 true JP5647098B2 (ja) 2014-12-24

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JP2014226368A Pending JP2015044847A (ja) 2008-03-21 2014-11-06 オピオイド拮抗薬とｍＴＯＲ阻害薬を用いた治療

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AU2009225434B2 (en) 2008-03-21 2014-05-22 The University Of Chicago Treatment with opioid antagonists and mTOR inhibitors
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CN102336760B (zh) * 2010-07-23 2016-04-06 重庆医药工业研究院有限责任公司 溴化吗啡喃季铵盐的制备方法
DK2716291T3 (da) 2012-10-08 2020-03-02 Univ Ulm Kombination af opioider og anticancer-lægemidler til cancerbehandling
US20140193410A1 (en) * 2013-01-09 2014-07-10 University Of Miami Compositions and Methods for the Regulation of T Regulatory Cells Using TL1A-Ig Fusion Protein
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WO2017083835A1 (en) * 2015-11-13 2017-05-18 The Trustees Of Columbia University In The City Of New York Inhibition of tor complex 2 increases immunity against bacterial infection
EP3484515A4 (en) * 2016-07-14 2020-06-17 Children's Hospital Medical Center METHOD FOR TREATING FIBROSE
JP7108631B2 (ja) 2017-01-06 2022-07-28 パルヴェラ セラピューティクス、インク． ｍＴＯＲ阻害剤の無水組成物およびその使用方法
JP2021530463A (ja) 2018-07-02 2021-11-11 パルヴェラ セラピューティクス、インク． ｍＴＯＲ阻害剤の無水組成物および使用方法

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EP2278966A2 (en) 2011-02-02
WO2009117669A3 (en) 2009-12-17
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AU2009225434A8 (en) 2011-02-17
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US20170065581A1 (en) 2017-03-09
CA2719134A1 (en) 2009-09-24
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US8685995B2 (en) 2014-04-01
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