JP5646502B2 - 神経因性疼痛を治療するための臍帯組織由来細胞 - Google Patents
神経因性疼痛を治療するための臍帯組織由来細胞 Download PDFInfo
- Publication number
- JP5646502B2 JP5646502B2 JP2011542518A JP2011542518A JP5646502B2 JP 5646502 B2 JP5646502 B2 JP 5646502B2 JP 2011542518 A JP2011542518 A JP 2011542518A JP 2011542518 A JP2011542518 A JP 2011542518A JP 5646502 B2 JP5646502 B2 JP 5646502B2
- Authority
- JP
- Japan
- Prior art keywords
- cells
- cell
- umbilical cord
- tissue
- derived
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 208000004296 neuralgia Diseases 0.000 title 1
- 208000021722 neuropathic pain Diseases 0.000 title 1
- 210000003954 umbilical cord Anatomy 0.000 title 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/44—Vessels; Vascular smooth muscle cells; Endothelial cells; Endothelial progenitor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Vascular Medicine (AREA)
- Virology (AREA)
- Developmental Biology & Embryology (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13916908P | 2008-12-19 | 2008-12-19 | |
| US61/139,169 | 2008-12-19 | ||
| PCT/US2009/068879 WO2010071862A1 (en) | 2008-12-19 | 2009-12-19 | Umbilical cord tissue derived cells for treating neuropathic pain and spasticity |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012512909A JP2012512909A (ja) | 2012-06-07 |
| JP2012512909A5 JP2012512909A5 (enExample) | 2012-07-19 |
| JP5646502B2 true JP5646502B2 (ja) | 2014-12-24 |
Family
ID=41682583
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011542518A Expired - Fee Related JP5646502B2 (ja) | 2008-12-19 | 2009-12-19 | 神経因性疼痛を治療するための臍帯組織由来細胞 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20190105351A9 (enExample) |
| EP (1) | EP2379087B1 (enExample) |
| JP (1) | JP5646502B2 (enExample) |
| CN (1) | CN102481321B (enExample) |
| AU (1) | AU2009327382B2 (enExample) |
| BR (1) | BRPI0923177A2 (enExample) |
| CA (1) | CA2747757C (enExample) |
| CY (1) | CY1116344T1 (enExample) |
| DK (1) | DK2379087T3 (enExample) |
| ES (1) | ES2520393T3 (enExample) |
| PT (1) | PT2379087E (enExample) |
| SI (1) | SI2379087T1 (enExample) |
| WO (1) | WO2010071862A1 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8491883B2 (en) * | 2003-06-27 | 2013-07-23 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of amyotrophic lateral sclerosis using umbilical derived cells |
| US9592258B2 (en) | 2003-06-27 | 2017-03-14 | DePuy Synthes Products, Inc. | Treatment of neurological injury by administration of human umbilical cord tissue-derived cells |
| US8790637B2 (en) | 2003-06-27 | 2014-07-29 | DePuy Synthes Products, LLC | Repair and regeneration of ocular tissue using postpartum-derived cells |
| US7875272B2 (en) * | 2003-06-27 | 2011-01-25 | Ethicon, Incorporated | Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells |
| PL1641914T3 (pl) | 2003-06-27 | 2017-01-31 | DePuy Synthes Products, Inc. | Komórki pochodzące z poporodowej tkanki łożyska oraz sposoby uzyskiwania i zastosowania tych komórek |
| US8518390B2 (en) | 2003-06-27 | 2013-08-27 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of stroke and other acute neural degenerative disorders via intranasal administration of umbilical cord-derived cells |
| EP1933852B1 (en) | 2005-09-27 | 2018-12-19 | TissueTech, Inc. | Amniotic membrane preparations and purified compositions and methods of use |
| US9125906B2 (en) | 2005-12-28 | 2015-09-08 | DePuy Synthes Products, Inc. | Treatment of peripheral vascular disease using umbilical cord tissue-derived cells |
| WO2008060541A2 (en) | 2006-11-13 | 2008-05-22 | Ethicon, Incorporated | In vitro expansion of postpartum-derived cells using microcarriers |
| CA2701435C (en) * | 2007-10-05 | 2017-06-20 | Ethicon, Inc. | Repair and regeneration of renal tissue using human umbilical cord tissue-derived cells |
| US8236538B2 (en) | 2007-12-20 | 2012-08-07 | Advanced Technologies And Regenerative Medicine, Llc | Methods for sterilizing materials containing biologically active agents |
| US10179900B2 (en) | 2008-12-19 | 2019-01-15 | DePuy Synthes Products, Inc. | Conditioned media and methods of making a conditioned media |
| CA2747794C (en) | 2008-12-19 | 2018-10-30 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of lung and pulmonary diseases and disorders |
| SG174551A1 (en) * | 2009-03-26 | 2011-10-28 | Ethicon Inc | Human umbilical cord tissue cells as therapy for alzheimer' s disease |
| WO2012149486A1 (en) | 2011-04-28 | 2012-11-01 | Tissuetech, Inc. | Methods of modulating bone remodeling |
| DK2714059T3 (en) * | 2011-06-01 | 2019-01-21 | Celularity Inc | TREATMENT OF PAIN WHEN USING PLACENT STAM CELLS |
| PH12014500301A1 (en) * | 2011-08-10 | 2014-05-19 | Depuy Synthes Products Llc | Treatment of peripheral vascular disease using umbilical cord tissue-derived cells |
| EP2863927A4 (en) | 2012-06-26 | 2015-12-02 | Rusty Property Holdings Pty Ltd | COMPOSITIONS AND METHODS FOR REDUCING THE FREQUENCY AND / OR INTENSITY OF THE CEPHALA |
| EP2756754B1 (de) | 2013-01-17 | 2017-01-04 | Vita 34 Ag | Verfahren zur Behandlung von Nabelschnurgewebe, insbesondere im Zusammenhang mit der Konservierung des Gewebes |
| US10039792B1 (en) * | 2013-03-16 | 2018-08-07 | Brahm Holdings, Llc | Methods for the treatment of inflammation and pain using human birth tissue material composition |
| US20160158292A1 (en) * | 2014-07-29 | 2016-06-09 | Ingeneron, Inc. | Method and apparatus for recovery of umbilical cord tissue derived regenerative cells and uses thereof |
| TW201642914A (zh) | 2015-02-23 | 2016-12-16 | 組織科技股份有限公司 | 用於治療眼部疾病及失調的裝置及方法 |
| CN106906180A (zh) * | 2016-12-28 | 2017-06-30 | 里程 | 一种具有生物活化作用的复合添加剂及其制备方法和用途 |
| CA3099387A1 (en) * | 2018-05-04 | 2019-11-07 | Figene, Llc | Pain-reducing effects of fibroblasts and treatment of pain |
| CN110772535A (zh) * | 2018-07-12 | 2020-02-11 | 南通大学 | 多系分化持续应激细胞在制备镇痛药物中的应用 |
| WO2021092199A1 (en) * | 2019-11-08 | 2021-05-14 | Kansas State University Research Foundation | Isolation, preservation, and expansion of canine umbilical cord mesenchymal stromal cells |
| CN112190694B (zh) * | 2020-09-17 | 2023-11-10 | 南通大学 | 细胞因子活化素c在治疗神经病理性疼痛方面的应用 |
| WO2022186946A1 (en) * | 2021-03-03 | 2022-09-09 | Axogen Corporation | Human umbilical cord-derived compositions and uses thereof for treating neuropathy |
| US20220280573A1 (en) * | 2021-03-03 | 2022-09-08 | Axogen Corporation | Human umbilical cord-derived compositions and uses thereof for treating neuropathy |
| CN114561355B (zh) * | 2022-01-23 | 2023-04-11 | 四川大学华西医院 | 一种脊髓瘢痕组织细胞急性快速分离方法 |
| EP4561595A2 (en) * | 2022-07-26 | 2025-06-04 | Biostem Technologies, Inc. | Human umbilical cord compositions and methods for intra-articular therapy |
Family Cites Families (98)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3665061A (en) * | 1969-07-16 | 1972-05-23 | United States Banknote Corp | Process for producing collagen sponges |
| JPS5651747B2 (enExample) * | 1973-05-31 | 1981-12-08 | ||
| US5902741A (en) * | 1986-04-18 | 1999-05-11 | Advanced Tissue Sciences, Inc. | Three-dimensional cartilage cultures |
| US5863531A (en) * | 1986-04-18 | 1999-01-26 | Advanced Tissue Sciences, Inc. | In vitro preparation of tubular tissue structures by stromal cell culture on a three-dimensional framework |
| US5192553A (en) * | 1987-11-12 | 1993-03-09 | Biocyte Corporation | Isolation and preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood and methods of therapeutic use |
| US5004681B1 (en) * | 1987-11-12 | 2000-04-11 | Biocyte Corp | Preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood |
| US20030032178A1 (en) * | 1988-08-04 | 2003-02-13 | Williams Robert Lindsay | In vitro propagation of embryonic stem cells |
| US4925677A (en) * | 1988-08-31 | 1990-05-15 | Theratech, Inc. | Biodegradable hydrogel matrices for the controlled release of pharmacologically active agents |
| US5486359A (en) * | 1990-11-16 | 1996-01-23 | Osiris Therapeutics, Inc. | Human mesenchymal stem cells |
| US5286632A (en) * | 1991-01-09 | 1994-02-15 | Jones Douglas H | Method for in vivo recombination and mutagenesis |
| US6399369B1 (en) * | 1991-07-08 | 2002-06-04 | Neurospheres Holdings Ltd. | Multipotent neural stem cell cDNA libraries |
| US5320962A (en) * | 1992-07-22 | 1994-06-14 | Duke University | DNA encoding the human A1 adenosine receptor |
| US5670483A (en) | 1992-12-28 | 1997-09-23 | Massachusetts Insititute Of Technology | Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor |
| US5955343A (en) | 1992-12-28 | 1999-09-21 | Massachusetts Institute Of Technology | Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor |
| US5707643A (en) * | 1993-02-26 | 1998-01-13 | Santen Pharmaceutical Co., Ltd. | Biodegradable scleral plug |
| JP3680114B2 (ja) * | 1993-09-17 | 2005-08-10 | 敏一 中村 | 脳神経障害治療剤 |
| US6686198B1 (en) * | 1993-10-14 | 2004-02-03 | President And Fellows Of Harvard College | Method of inducing and maintaining neuronal cells |
| US6703017B1 (en) * | 1994-04-28 | 2004-03-09 | Ixion Biotechnology, Inc. | Reversal of insulin-dependent diabetes by islet-producing stem cells, islet progenitor cells and islet-like structures |
| DK0952792T3 (da) * | 1994-06-06 | 2003-12-08 | Osiris Therapeutics Inc | Biomatrix til vævsregeneration |
| US6309853B1 (en) | 1994-08-17 | 2001-10-30 | The Rockfeller University | Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof |
| US5725493A (en) * | 1994-12-12 | 1998-03-10 | Avery; Robert Logan | Intravitreal medicine delivery |
| US5843780A (en) * | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
| US5906934A (en) * | 1995-03-14 | 1999-05-25 | Morphogen Pharmaceuticals, Inc. | Mesenchymal stem cells for cartilage repair |
| US5869079A (en) * | 1995-06-02 | 1999-02-09 | Oculex Pharmaceuticals, Inc. | Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents |
| US5641750A (en) * | 1995-11-29 | 1997-06-24 | Amgen Inc. | Methods for treating photoreceptors using glial cell line-derived neurotrophic factor (GDNF) protein product |
| US6200606B1 (en) * | 1996-01-16 | 2001-03-13 | Depuy Orthopaedics, Inc. | Isolation of precursor cells from hematopoietic and nonhematopoietic tissues and their use in vivo bone and cartilage regeneration |
| US6358737B1 (en) * | 1996-07-31 | 2002-03-19 | Board Of Regents, The University Of Texas System | Osteocyte cell lines |
| US6787355B1 (en) * | 1996-08-26 | 2004-09-07 | Mcgill University | Multipotent neural stem cells from peripheral tissues and uses thereof |
| JP2002513383A (ja) * | 1997-05-21 | 2002-05-08 | スローン−ケタリング・インスティテュート・フォー・キャンサー・リサーチ | 患者の脳組織でのアスコルビン酸の濃度を増加させる方法 |
| AU738334B2 (en) * | 1997-05-30 | 2001-09-13 | Osteobiologics, Inc. | Fiber-reinforced, porous, biodegradable implant device |
| US5902598A (en) * | 1997-08-28 | 1999-05-11 | Control Delivery Systems, Inc. | Sustained release drug delivery devices |
| EP1036163B1 (en) * | 1997-12-02 | 2010-08-18 | Artecel Sciences, Inc. | Differentiation of adipose stromal cells into osteoblasts and uses thereof |
| US6059968A (en) * | 1998-01-20 | 2000-05-09 | Baxter International Inc. | Systems for processing and storing placenta/umbilical cord blood |
| US6355239B1 (en) * | 1998-03-13 | 2002-03-12 | Osiris Therapeutics, Inc. | Uses for non-autologous mesenchymal stem cells |
| US6171610B1 (en) * | 1998-04-24 | 2001-01-09 | University Of Massachusetts | Guided development and support of hydrogel-cell compositions |
| WO1999056759A1 (en) * | 1998-05-07 | 1999-11-11 | University Of South Florida | Bone marrow cells as a source of neurons for brain and spinal cord repair |
| AU4221399A (en) * | 1998-05-29 | 1999-12-13 | Osiris Therapeutics, Inc. | Human cd45+ and/or fibroblast + mesenchymal stem cells |
| US20040037818A1 (en) * | 1998-07-30 | 2004-02-26 | Brand Stephen J. | Treatment for diabetes |
| US5958767A (en) * | 1998-08-14 | 1999-09-28 | The Children's Medical Center Corp. | Engraftable human neural stem cells |
| US6610540B1 (en) | 1998-11-18 | 2003-08-26 | California Institute Of Technology | Low oxygen culturing of central nervous system progenitor cells |
| US20030007954A1 (en) * | 1999-04-12 | 2003-01-09 | Gail K. Naughton | Methods for using a three-dimensional stromal tissue to promote angiogenesis |
| JP2002542349A (ja) * | 1999-04-16 | 2002-12-10 | ダブリューエム・マーシュ・ライス・ユニバーシティー | ポリ(プロピレンフマラート)−ジアクリレートマクロマーで交差結合された生体分解性のポリ(プロピレンフマラート)ネットワーク |
| US6287340B1 (en) * | 1999-05-14 | 2001-09-11 | Trustees Of Tufts College | Bioengineered anterior cruciate ligament |
| US6372494B1 (en) * | 1999-05-14 | 2002-04-16 | Advanced Tissue Sciences, Inc. | Methods of making conditioned cell culture medium compositions |
| US6355699B1 (en) * | 1999-06-30 | 2002-03-12 | Ethicon, Inc. | Process for manufacturing biomedical foams |
| US6333029B1 (en) * | 1999-06-30 | 2001-12-25 | Ethicon, Inc. | Porous tissue scaffoldings for the repair of regeneration of tissue |
| US7621606B2 (en) * | 2001-08-27 | 2009-11-24 | Advanced Cell Technology, Inc. | Trans-differentiation and re-differentiation of somatic cells and production of cells for cell therapies |
| US6555374B1 (en) | 1999-08-19 | 2003-04-29 | Artecel Sciences, Inc. | Multiple mesodermal lineage differentiation potentials for adipose tissue-derived stromal cells and uses thereof |
| US20030129745A1 (en) * | 1999-10-28 | 2003-07-10 | Robl James M. | Gynogenetic or androgenetic production of pluripotent cells and cell lines, and use thereof to produce differentiated cells and tissues |
| CN100475953C (zh) * | 1999-12-06 | 2009-04-08 | 通用医疗公司 | 胰腺干细胞 |
| US20030082155A1 (en) * | 1999-12-06 | 2003-05-01 | Habener Joel F. | Stem cells of the islets of langerhans and their use in treating diabetes mellitus |
| US7544509B2 (en) * | 2000-01-24 | 2009-06-09 | Mcgill University | Method for preparing stem cell preparations |
| EP1263930A4 (en) * | 2000-03-09 | 2004-07-21 | Saneron Ccel Therapeutics Inc | HUMAN CORD BLOOD BLOOD AS A SOURCE FOR NEURAL TISSUE FOR HEALING THE BRAIN AND BACK MARK |
| US6673606B1 (en) * | 2000-04-12 | 2004-01-06 | The Children's Hospital Of Philadelphia | Therapeutic uses for mesenchymal stromal cells |
| US6375972B1 (en) * | 2000-04-26 | 2002-04-23 | Control Delivery Systems, Inc. | Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof |
| US6759039B2 (en) * | 2000-06-30 | 2004-07-06 | Amcyte, Inc. | Culturing pancreatic stem cells having a specified, intermediate stage of development |
| US7449180B2 (en) | 2001-02-06 | 2008-11-11 | John Kisiday | Macroscopic scaffold containing amphiphilic peptides encapsulating cells |
| DE60230593D1 (de) | 2001-02-06 | 2009-02-12 | Massachusetts Inst Technology | Peptidgerüstverkapselung von gewebszellen und verwendungen davon |
| EP2336299A1 (en) * | 2001-02-14 | 2011-06-22 | Anthrogenesis Corporation | Post-partum mammalian placenta, its use and placental stem cells therefrom |
| SG125066A1 (en) * | 2001-04-19 | 2006-09-29 | Lintec Corp | Adhesive sheet for precision electronic member |
| US20030022369A1 (en) * | 2001-05-18 | 2003-01-30 | Helen Fillmore | Differentiation of specialized dermal and epidermal cells into neuronal cells |
| JP2005515753A (ja) * | 2001-05-25 | 2005-06-02 | サイセラ,インコーポレイテッド | 幹細胞分化 |
| US6835711B2 (en) * | 2001-06-28 | 2004-12-28 | Yeda Research And Development Co. Ltd. | Use of poly-Glu,Tyr for neuroprotective therapy |
| US20030104997A1 (en) * | 2001-09-05 | 2003-06-05 | Black Ira B. | Multi-lineage directed induction of bone marrow stromal cell differentiation |
| US9969980B2 (en) | 2001-09-21 | 2018-05-15 | Garnet Biotherapeutics | Cell populations which co-express CD49c and CD90 |
| US7129034B2 (en) * | 2001-10-25 | 2006-10-31 | Cedars-Sinai Medical Center | Differentiation of whole bone marrow |
| JP3728750B2 (ja) * | 2001-11-22 | 2005-12-21 | ニプロ株式会社 | 培養皮膚及びその製造方法 |
| JP2005512592A (ja) * | 2001-12-21 | 2005-05-12 | マウント・シナイ・ホスピタル | 細胞性組成物ならびに細胞性組成物の作製法および細胞性組成物の使用法 |
| US20030162290A1 (en) * | 2002-01-25 | 2003-08-28 | Kazutomo Inoue | Method for inducing differentiation of embryonic stem cells into functioning cells |
| US20040029269A1 (en) * | 2002-05-07 | 2004-02-12 | Goldman Steven A | Promoter-based isolation, purification, expansion, and transplantation of neuronal progenitor cells, oligodendrocyte progenitor cells, or neural stem cells from a population of embryonic stem cells |
| AU2003233119A1 (en) * | 2002-05-08 | 2003-11-11 | Neuronova Ab | Modulation of neural stem cells with s1p or lpa receptor agonists |
| WO2003102151A2 (en) * | 2002-05-30 | 2003-12-11 | Celgene Corporation | Modulating cell differentiation and treating myeloprolifertive disorders with jnk/mkk inhibitors |
| US7410797B2 (en) * | 2002-06-11 | 2008-08-12 | Ogle Roy C | Meningeal-derived stem cells |
| US7285415B2 (en) * | 2002-07-11 | 2007-10-23 | The Regents Of The University Of California | Oligodendrocytes derived from human embryonic stem cells for remyelination and treatment of spinal cord injury |
| US7390659B2 (en) * | 2002-07-16 | 2008-06-24 | The Trustees Of Columbia University In The City Of New York | Methods for inducing differentiation of embryonic stem cells and uses thereof |
| JP2006508648A (ja) * | 2002-08-28 | 2006-03-16 | ユニヴァーシティ オヴ フロリダ | 肝幹細胞からの神経新生 |
| US9969977B2 (en) | 2002-09-20 | 2018-05-15 | Garnet Biotherapeutics | Cell populations which co-express CD49c and CD90 |
| NZ566132A (en) * | 2003-02-13 | 2009-09-25 | Anthrogenesis Corp | Use of umbilical cord blood to treat inflammation, ParkinsonÆs disease or diabetes |
| US7875272B2 (en) * | 2003-06-27 | 2011-01-25 | Ethicon, Incorporated | Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells |
| PL1641914T3 (pl) * | 2003-06-27 | 2017-01-31 | DePuy Synthes Products, Inc. | Komórki pochodzące z poporodowej tkanki łożyska oraz sposoby uzyskiwania i zastosowania tych komórek |
| US8518390B2 (en) * | 2003-06-27 | 2013-08-27 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of stroke and other acute neural degenerative disorders via intranasal administration of umbilical cord-derived cells |
| US20050089513A1 (en) * | 2003-10-28 | 2005-04-28 | Norio Sakuragawa | Side population cells originated from human amnion and their uses |
| US7691629B2 (en) * | 2004-11-17 | 2010-04-06 | Neuralstem, Inc. | Transplantation of human neural cells for treatment of neurodegenerative conditions |
| EP1827108B1 (en) * | 2004-11-29 | 2015-04-08 | Yeda Research And Development Co., Ltd. | Induction of neurogenesis and stem cell therapy in combination with copolymer 1 |
| US7833513B2 (en) * | 2004-12-03 | 2010-11-16 | Rhode Island Hospital | Treatment of Alzheimer's Disease |
| JP5425399B2 (ja) * | 2004-12-23 | 2014-02-26 | エシコン・インコーポレイテッド | 産褥由来細胞を用いたパーキンソン病および関連の障害の治療 |
| GB2440089B8 (en) * | 2005-05-05 | 2012-09-05 | Univ Goettingen Georg August | Regeneration system, its production and use |
| WO2007016245A2 (en) * | 2005-07-29 | 2007-02-08 | Vivicells International, Llc | Reprogramming of adult or neonic stem cells and methods of use |
| AU2006236006B2 (en) * | 2006-04-13 | 2012-09-06 | The University Of Queensland | Cyclised a-conotoxin peptides |
| AU2007297575A1 (en) * | 2006-06-26 | 2008-03-27 | Lifescan, Inc. | Pluripotent stem cell culture |
| US8372399B2 (en) * | 2006-08-31 | 2013-02-12 | Cardiac Pacemakers, Inc. | Bispecific antibodies and agents to enhance stem cell homing |
| SI2078073T1 (sl) * | 2006-10-12 | 2013-11-29 | Ethicon, Inc. | Celice, pridobljene iz ledvice, in postopki uporabe pri popravljanju tkiv in regeneraciji |
| US20080092653A1 (en) * | 2006-10-18 | 2008-04-24 | Scintrex Limited | Method of reducing the drift rate of accelerometer and accelerometer with reduced drift rate |
| US8747905B2 (en) * | 2006-10-27 | 2014-06-10 | Emory University | Therapeutic use of CD31 expressing cells |
| ME01562B (me) * | 2007-02-12 | 2014-09-20 | Anthrogenesis Corp | Liječenje protuupalnih bolesti putem matičnih stanica posteljice |
| US20080305148A1 (en) * | 2007-03-19 | 2008-12-11 | National Yang Ming University | Treatment of spinal injuries using human umbilical mesenchymal stem cells |
| WO2009085860A1 (en) * | 2007-12-27 | 2009-07-09 | Ethicon, Incorporated | Treatment of intervertebral disc degeneration using human umbilical cord tissue-derived cells |
| SG174551A1 (en) * | 2009-03-26 | 2011-10-28 | Ethicon Inc | Human umbilical cord tissue cells as therapy for alzheimer' s disease |
-
2009
- 2009-12-19 AU AU2009327382A patent/AU2009327382B2/en not_active Ceased
- 2009-12-19 DK DK09795654.4T patent/DK2379087T3/da active
- 2009-12-19 US US12/642,775 patent/US20190105351A9/en not_active Abandoned
- 2009-12-19 EP EP09795654.4A patent/EP2379087B1/en not_active Not-in-force
- 2009-12-19 SI SI200931065T patent/SI2379087T1/sl unknown
- 2009-12-19 PT PT97956544T patent/PT2379087E/pt unknown
- 2009-12-19 CA CA2747757A patent/CA2747757C/en active Active
- 2009-12-19 JP JP2011542518A patent/JP5646502B2/ja not_active Expired - Fee Related
- 2009-12-19 ES ES09795654.4T patent/ES2520393T3/es active Active
- 2009-12-19 CN CN200980156986.9A patent/CN102481321B/zh not_active Expired - Fee Related
- 2009-12-19 BR BRPI0923177-3A patent/BRPI0923177A2/pt not_active Application Discontinuation
- 2009-12-19 WO PCT/US2009/068879 patent/WO2010071862A1/en not_active Ceased
-
2014
- 2014-11-18 CY CY20141100961T patent/CY1116344T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2379087B1 (en) | 2014-08-20 |
| CA2747757C (en) | 2020-11-03 |
| JP2012512909A (ja) | 2012-06-07 |
| AU2009327382B2 (en) | 2014-07-17 |
| ES2520393T3 (es) | 2014-11-11 |
| CY1116344T1 (el) | 2017-02-08 |
| US20190105351A9 (en) | 2019-04-11 |
| DK2379087T3 (da) | 2014-11-10 |
| BRPI0923177A2 (pt) | 2020-08-25 |
| CN102481321A (zh) | 2012-05-30 |
| US20100159025A1 (en) | 2010-06-24 |
| EP2379087A1 (en) | 2011-10-26 |
| SI2379087T1 (sl) | 2015-01-30 |
| CA2747757A1 (en) | 2010-06-24 |
| PT2379087E (pt) | 2014-12-02 |
| CN102481321B (zh) | 2017-12-19 |
| WO2010071862A1 (en) | 2010-06-24 |
| AU2009327382A1 (en) | 2011-08-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5646502B2 (ja) | 神経因性疼痛を治療するための臍帯組織由来細胞 | |
| JP6095893B2 (ja) | 傷害後の神経組織の再生および修復 | |
| JP5908394B2 (ja) | アルツハイマー病の療法としてのヒト臍帯組織細胞 | |
| JP5518893B2 (ja) | 肺ならびに肺の疾患および障害の治療 | |
| JP5425399B2 (ja) | 産褥由来細胞を用いたパーキンソン病および関連の障害の治療 | |
| RU2645079C2 (ru) | Лечение дегенеративных изменений межпозвоночных дисков с использованием клеток, полученных из ткани пуповины человека | |
| JP2018118984A (ja) | 肺疾患及び肺障害の炎症促進性メディエータのhUTC調節 | |
| CN103889433B (zh) | 使用脐带组织来源的细胞治疗外周血管疾病 | |
| US9592258B2 (en) | Treatment of neurological injury by administration of human umbilical cord tissue-derived cells |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20120330 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20120330 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20130308 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20130723 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20131023 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20131030 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20131122 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20131224 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20140324 |
|
| A711 | Notification of change in applicant |
Free format text: JAPANESE INTERMEDIATE CODE: A711 Effective date: 20140723 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20140826 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20140911 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20141007 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20141105 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 5646502 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| LAPS | Cancellation because of no payment of annual fees |