JP5618981B2 - 花粉シーズン開始後の初回投薬での粘膜のアレルゲン−特異的免疫療法 - Google Patents

花粉シーズン開始後の初回投薬での粘膜のアレルゲン−特異的免疫療法 Download PDF

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Publication number
JP5618981B2
JP5618981B2 JP2011503429A JP2011503429A JP5618981B2 JP 5618981 B2 JP5618981 B2 JP 5618981B2 JP 2011503429 A JP2011503429 A JP 2011503429A JP 2011503429 A JP2011503429 A JP 2011503429A JP 5618981 B2 JP5618981 B2 JP 5618981B2
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allergen
administration
solid
season
medicament
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JP2011516521A (ja
JP2011516521A5 (enExample
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ヴューステンベルク，アイク，ギュンター
プッヘルト，エクハルト−カール，アルブレヒト
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ALK Abello AS
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ALK Abello AS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2011503429A 2008-04-11 2009-04-08 花粉シーズン開始後の初回投薬での粘膜のアレルゲン−特異的免疫療法 Expired - Fee Related JP5618981B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US4440108P 2008-04-11 2008-04-11
US61/044,401 2008-04-11
DKPA200800533 2008-04-11
DKPA200800533 2008-04-11
PCT/EP2009/054186 WO2009124954A1 (en) 2008-04-11 2009-04-08 Mucosomal allergen-specific immunotherapy with initial dosing after start of pollen season

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014187908A Division JP2015013891A (ja) 2008-04-11 2014-09-16 花粉シーズン開始後の初回投薬での粘膜のアレルゲン−特異的免疫療法

Publications (3)

Publication Number Publication Date
JP2011516521A JP2011516521A (ja) 2011-05-26
JP2011516521A5 JP2011516521A5 (enExample) 2012-05-31
JP5618981B2 true JP5618981B2 (ja) 2014-11-05

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JP2011503429A Expired - Fee Related JP5618981B2 (ja) 2008-04-11 2009-04-08 花粉シーズン開始後の初回投薬での粘膜のアレルゲン−特異的免疫療法
JP2014187908A Pending JP2015013891A (ja) 2008-04-11 2014-09-16 花粉シーズン開始後の初回投薬での粘膜のアレルゲン−特異的免疫療法

Family Applications After (1)

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JP2014187908A Pending JP2015013891A (ja) 2008-04-11 2014-09-16 花粉シーズン開始後の初回投薬での粘膜のアレルゲン−特異的免疫療法

Country Status (12)

Country Link
US (2) US9248097B2 (enExample)
EP (1) EP2265285B1 (enExample)
JP (2) JP5618981B2 (enExample)
CN (1) CN102014954A (enExample)
AU (1) AU2009235490B2 (enExample)
BR (1) BRPI0911433A2 (enExample)
CA (1) CA2720455A1 (enExample)
DE (1) DE202008006598U1 (enExample)
EA (1) EA019202B1 (enExample)
ES (1) ES2406391T3 (enExample)
MX (1) MX2010011012A (enExample)
WO (1) WO2009124954A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
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JP2015013891A (ja) * 2008-04-11 2015-01-22 アルク−アベッロ エイ／エスＡｌｋ−Ａｂｅｌｌｏ Ａ／Ｓ 花粉シーズン開始後の初回投薬での粘膜のアレルゲン−特異的免疫療法

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WO2004047793A1 (en) * 2002-11-26 2004-06-10 Alk-Abelló A/S Pharmaceutical allergen product
US7608693B2 (en) 2006-10-02 2009-10-27 Regeneron Pharmaceuticals, Inc. High affinity human antibodies to human IL-4 receptor
EP2627354B1 (en) * 2010-10-15 2015-07-15 ALK-Abelló A/S Suppression of a type 1 hypersensitivity immune response with an unrelated antigen
US20120100164A1 (en) 2010-10-15 2012-04-26 Alk-Abello A/S Suppression of a hypersensitivity immune response with unrelated antigen derived from allergen source material
WO2012148549A1 (en) 2011-02-25 2012-11-01 Benaroya Research Institute Detection of an immune response
JP2012240975A (ja) * 2011-05-20 2012-12-10 Nitto Denko Corp 医薬組成物及びゼリー状製剤
JP2012240978A (ja) * 2011-05-20 2012-12-10 Nitto Denko Corp 医薬組成物及びゼリー状製剤
SG10201605350UA (en) 2012-01-16 2016-08-30 Mckenna Elizabeth Compositions and Methods for the Treatment of Hepatic Diseases and Disorders
US12268718B2 (en) 2012-01-16 2025-04-08 Labyrinth Holdings Llc Control of cellular redox levels
KR102307248B1 (ko) 2012-08-21 2021-10-01 사노피 바이오테크놀로지 Il-4r 길항제의 투여에 의한 천식의 치료 또는 예방 방법
NZ630178A (en) 2012-09-07 2017-06-30 Regeneron Pharma Methods for treating atopic dermatitis by administering an il-4r antagonist
WO2014047588A1 (en) 2012-09-21 2014-03-27 Elizabeth Mckenna Naturally occurring cpg oligonucleotide compositions and therapeutic applications thereof
TWI755763B (zh) 2013-06-04 2022-02-21 美商再生元醫藥公司 藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法
TWI682781B (zh) 2013-07-11 2020-01-21 美商再生元醫藥公司 藉由投與ｉｌ－４ｒ抑制劑治療嗜酸性食道炎的方法
KR20160120735A (ko) 2014-02-28 2016-10-18 리제너론 파아마슈티컬스, 인크. Ｉｌ-4ｒ 길항제의 투여에 의한 피부 감염의 치료 방법
CA2967602C (en) 2014-11-14 2024-09-24 Regeneron Pharmaceuticals, Inc. METHODS OF TREATMENT OF CHRONIC SINUSITIS WITH NASAL POLYPOSIS BY ADMINISTRATION OF AN IL-4R ANTAGONIST
US11771743B2 (en) 2016-09-01 2023-10-03 Regeneron Pharmaceuticals, Inc. Methods for preventing or treating allergy by administering an IL-4R antagonist
US10485844B2 (en) 2016-09-22 2019-11-26 Regeneron Pharmaceuticals, Inc. Methods for treating severe atopic dermatitis by administering an IL-4R inhibitor
TWI857389B (zh) 2016-12-01 2024-10-01 美商再生元醫藥公司 治療發炎症狀的方法
WO2019028367A1 (en) 2017-08-04 2019-02-07 Regeneron Pharmaceuticals, Inc. METHODS OF TREATING ESOPHAGITIS WITH ACTIVE EOSINOPHILES
EP4344706A3 (en) 2017-10-30 2024-05-22 Sanofi Biotechnology Methods for treating or preventing asthma by administering an il-4r antagonist
CN120227453A (zh) 2018-05-13 2025-07-01 瑞泽恩制药公司 用于通过施用il-4r抑制剂治疗特应性皮炎的方法
KR20210143246A (ko) 2019-03-21 2021-11-26 리제너론 파아마슈티컬스, 인크. 알레르기 치료용 il-4/il-13 경로 억제제 및 형질 세포 절제의 병용
BR112022000740A2 (pt) 2019-07-16 2022-07-05 Sanofi Biotechnology Métodos para tratamento ou prevenção de asma por administração de um antagonista de il-4r
EP4010373A1 (en) 2019-08-05 2022-06-15 Regeneron Pharmaceuticals, Inc. Methods for treating atopic dermatitis by administering an il-4r antagonist
KR20220042217A (ko) 2019-08-05 2022-04-04 리제너론 파아마슈티컬스, 인크. Il-4r 길항제를 투여함에 의해 알레르기를 치료하고 알레르겐-특이적 면역치료요법을 증진시키기 위한 방법
EP4513185A1 (en) * 2023-08-22 2025-02-26 Luxembourg Institute of Health (LIH) Early response biomarkers for allergen immunotherapy

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JPH0959179A (ja) * 1995-08-28 1997-03-04 Japan Tobacco Inc スギ花粉症予防性を有する口腔衛生剤
DK1062341T3 (da) 1998-03-16 2008-11-03 Alk Abello As Muterede rekombinante allergener
FR2778244B1 (fr) 1998-04-30 2000-07-13 Univ Joseph Fourier Procede d'excitation d'une cavite optique pour la detection de gaz a l'etat de traces
DE60136653D1 (de) 2000-11-16 2009-01-02 Alk Abello As Mutante allergene
EP1504089A2 (en) 2002-05-16 2005-02-09 Alk Abell A/S Allergen mutants
WO2004047793A1 (en) * 2002-11-26 2004-06-10 Alk-Abelló A/S Pharmaceutical allergen product
WO2005077410A1 (en) 2004-02-06 2005-08-25 Greer Laboratories, Inc. Methods and compositions for dosing of allergens
BRPI0508078A (pt) * 2004-02-26 2007-07-17 Alk Abello As método para avaliar o potencial terapêutico de uma vacina para administração mucosa
US20060115499A1 (en) 2004-09-27 2006-06-01 Alk-Abello A/S Liquid allergy vaccine formulation for oromucosal administration
JP5628473B2 (ja) 2004-11-10 2014-11-19 アルク−アベッロ エイ／エスＡｌｋ−Ａｂｅｌｌｏ Ａ／Ｓ アレルギーワクチンの粘膜投与によるアレルギーの予防治療方法
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CN101098711A (zh) * 2005-01-07 2008-01-02 阿尔克-阿贝洛有限公司 通过口粘膜施用变态反应疫苗预防性治疗变态反应的方法
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015013891A (ja) * 2008-04-11 2015-01-22 アルク−アベッロ エイ／エスＡｌｋ−Ａｂｅｌｌｏ Ａ／Ｓ 花粉シーズン開始後の初回投薬での粘膜のアレルゲン−特異的免疫療法

Also Published As

Publication number Publication date
JP2011516521A (ja) 2011-05-26
CN102014954A (zh) 2011-04-13
EP2265285B1 (en) 2013-03-20
EA019202B1 (ru) 2014-01-30
US9248097B2 (en) 2016-02-02
DE202008006598U1 (de) 2008-10-02
WO2009124954A1 (en) 2009-10-15
JP2015013891A (ja) 2015-01-22
EP2265285A1 (en) 2010-12-29
CA2720455A1 (en) 2009-10-15
US20110142934A1 (en) 2011-06-16
US20140127298A1 (en) 2014-05-08
HK1147946A1 (en) 2011-08-26
ES2406391T3 (es) 2013-06-06
EA201071182A1 (ru) 2011-06-30
AU2009235490A1 (en) 2009-10-15
BRPI0911433A2 (pt) 2016-07-26
AU2009235490B2 (en) 2013-10-24
MX2010011012A (es) 2010-11-12

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