JP5588619B2 - ｐＨ応答性リポソーム - Google Patents

ｐＨ応答性リポソーム Download PDF

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Publication number
JP5588619B2
JP5588619B2 JP2009058063A JP2009058063A JP5588619B2 JP 5588619 B2 JP5588619 B2 JP 5588619B2 JP 2009058063 A JP2009058063 A JP 2009058063A JP 2009058063 A JP2009058063 A JP 2009058063A JP 5588619 B2 JP5588619 B2 JP 5588619B2
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JP
Japan
Prior art keywords
liposome
amphiphilic molecule
responsive
group
dispersion
Prior art date
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Active
Application number
JP2009058063A
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English (en)
Japanese (ja)
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JP2010209012A (ja
JP2010209012A5 (enExample
Inventor
真司 武岡
洋輔 小幡
識 中川
真也 大坪
祐治 川▲崎▼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanotheta Co Ltd
Ichimaru Pharcos Co Ltd
Original Assignee
Nanotheta Co Ltd
Ichimaru Pharcos Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanotheta Co Ltd, Ichimaru Pharcos Co Ltd filed Critical Nanotheta Co Ltd
Priority to JP2009058063A priority Critical patent/JP5588619B2/ja
Priority to KR1020117023505A priority patent/KR20110128335A/ko
Priority to US13/255,231 priority patent/US8871252B2/en
Priority to PCT/JP2010/054042 priority patent/WO2010104128A1/ja
Priority to EP10750881.4A priority patent/EP2407158A4/en
Publication of JP2010209012A publication Critical patent/JP2010209012A/ja
Publication of JP2010209012A5 publication Critical patent/JP2010209012A5/ja
Application granted granted Critical
Publication of JP5588619B2 publication Critical patent/JP5588619B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
JP2009058063A 2009-03-11 2009-03-11 ｐＨ応答性リポソーム Active JP5588619B2 (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2009058063A JP5588619B2 (ja) 2009-03-11 2009-03-11 ｐＨ応答性リポソーム
KR1020117023505A KR20110128335A (ko) 2009-03-11 2010-03-10 ｐＨ 응답성 리포솜
US13/255,231 US8871252B2 (en) 2009-03-11 2010-03-10 pH-responsive liposome
PCT/JP2010/054042 WO2010104128A1 (ja) 2009-03-11 2010-03-10 ｐＨ応答性リポソーム
EP10750881.4A EP2407158A4 (en) 2009-03-11 2010-03-10 LIPOSOME SENSITIVE TO PH

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2009058063A JP5588619B2 (ja) 2009-03-11 2009-03-11 ｐＨ応答性リポソーム

Publications (3)

Publication Number Publication Date
JP2010209012A JP2010209012A (ja) 2010-09-24
JP2010209012A5 JP2010209012A5 (enExample) 2012-04-19
JP5588619B2 true JP5588619B2 (ja) 2014-09-10

Family

ID=42728416

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009058063A Active JP5588619B2 (ja) 2009-03-11 2009-03-11 ｐＨ応答性リポソーム

Country Status (5)

Country Link
US (1) US8871252B2 (enExample)
EP (1) EP2407158A4 (enExample)
JP (1) JP5588619B2 (enExample)
KR (1) KR20110128335A (enExample)
WO (1) WO2010104128A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200050982A (ko) 2017-09-04 2020-05-12 이치마루 화루코스 가부시키가이샤 pH 감수성 리포솜 및 그 제조 방법

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6339884B2 (ja) * 2014-07-17 2018-06-06 富士フイルム株式会社 イミダゾール化合物およびそれを含有するリポソーム
GB201614120D0 (en) * 2016-08-18 2016-10-05 Univ Of Kwazulu-Natal pH-responsive lipids
JP6462073B1 (ja) * 2017-09-04 2019-01-30 一丸ファルコス株式会社 ｐＨ感受性リポソームの製造方法
JP6399530B1 (ja) * 2017-09-04 2018-10-03 一丸ファルコス株式会社 ｐＨ感受性リポソーム
JP7406057B2 (ja) 2021-03-03 2023-12-27 東洋ビューティ株式会社 外用微粒子カプセル製剤及び皮膚外用剤
CN119552796A (zh) * 2024-11-29 2025-03-04 艾美行动生物制药有限公司 一种用于细胞培养添加物包载的pH敏感脂质体及制备方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8382004B2 (en) * 2001-04-04 2013-02-26 Graftech International Holdings Inc. Flexible graphite flooring heat spreader
JP5093547B2 (ja) * 2001-08-24 2012-12-12 日本ケミカルリサーチ株式会社 両イオン性脂質およびその用途
DE10207177A1 (de) * 2002-02-19 2003-09-04 Novosom Ag Fakultativ kationische Lipide
RU2424792C2 (ru) * 2004-05-03 2011-07-27 Хермес Байесайенсиз, Инк. Липосомы, используемые для доставки лекарственных средств
US8658203B2 (en) * 2004-05-03 2014-02-25 Merrimack Pharmaceuticals, Inc. Liposomes useful for drug delivery to the brain
CA2586708A1 (en) * 2004-11-05 2006-05-11 Novosom Ag Improvements in or relating to pharmaceutical compositions comprising an oligonucleotide as an active agent
WO2006118327A1 (ja) 2005-04-27 2006-11-09 Oxygenix Co Ltd カチオン性アミノ酸型脂質
EP1764089A1 (en) 2005-09-15 2007-03-21 Novosom AG Serum stable liposomes comprising amphoter II lipid mixtures
WO2007031333A2 (en) * 2005-09-15 2007-03-22 Novosom Ag Improvements in or relating to amphoteric liposomes
JP5122474B2 (ja) * 2005-12-01 2013-01-16 プロネイ・セラピューティクス・インコーポレイテッド 両性リポソーム製剤
JP5253716B2 (ja) * 2006-02-09 2013-07-31 日本ケミカルリサーチ株式会社 ｐＨ応答性分子集合体
US20080145413A1 (en) 2006-12-19 2008-06-19 Steffen Panzner Lipids and lipid assemblies comprising transfection enhancer elements
US8193246B2 (en) * 2006-12-19 2012-06-05 Marina Biotech, Inc. Lipids and lipid assemblies comprising transfection enhancer elements
JP5241711B2 (ja) * 2007-05-17 2013-07-17 学校法人早稲田大学 両親媒性分子、それを含む分子集合体及びその用途
AU2008309880B2 (en) 2007-10-12 2014-07-10 Biontech Delivery Technologies Gmbh Amphoteric liposomes comprising neutral lipids
WO2009051712A1 (en) * 2007-10-15 2009-04-23 Pronai Therapeutics, Inc. Dnai amphoteric liposome formulation
US20100129430A1 (en) * 2008-11-24 2010-05-27 Stavroula Sofou Liposome drug carriers with ph-sensitivity

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200050982A (ko) 2017-09-04 2020-05-12 이치마루 화루코스 가부시키가이샤 pH 감수성 리포솜 및 그 제조 방법

Also Published As

Publication number Publication date
EP2407158A1 (en) 2012-01-18
JP2010209012A (ja) 2010-09-24
US8871252B2 (en) 2014-10-28
US20120064148A1 (en) 2012-03-15
WO2010104128A1 (ja) 2010-09-16
EP2407158A4 (en) 2013-09-04
KR20110128335A (ko) 2011-11-29

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