KR20110128335A - ｐＨ 응답성 리포솜 - Google Patents

ｐＨ 응답성 리포솜 Download PDF

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Publication number
KR20110128335A
KR20110128335A KR1020117023505A KR20117023505A KR20110128335A KR 20110128335 A KR20110128335 A KR 20110128335A KR 1020117023505 A KR1020117023505 A KR 1020117023505A KR 20117023505 A KR20117023505 A KR 20117023505A KR 20110128335 A KR20110128335 A KR 20110128335A
Authority
KR
South Korea
Prior art keywords
zwitterionic
responsive
liposomes
liposome
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020117023505A
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English (en)
Korean (ko)
Inventor
신지 다케오카
요우스케 오바타
사토루 나카가와
신야 오츠보
유지 가와사키
Original Assignee
가부시키가이샤 바이오나노시타
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 가부시키가이샤 바이오나노시타 filed Critical 가부시키가이샤 바이오나노시타
Publication of KR20110128335A publication Critical patent/KR20110128335A/ko
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
KR1020117023505A 2009-03-11 2010-03-10 ｐＨ 응답성 리포솜 Ceased KR20110128335A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2009058063A JP5588619B2 (ja) 2009-03-11 2009-03-11 ｐＨ応答性リポソーム
JPJP-P-2009-058063 2009-03-11

Publications (1)

Publication Number Publication Date
KR20110128335A true KR20110128335A (ko) 2011-11-29

Family

ID=42728416

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020117023505A Ceased KR20110128335A (ko) 2009-03-11 2010-03-10 ｐＨ 응답성 리포솜

Country Status (5)

Country Link
US (1) US8871252B2 (enExample)
EP (1) EP2407158A4 (enExample)
JP (1) JP5588619B2 (enExample)
KR (1) KR20110128335A (enExample)
WO (1) WO2010104128A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6339884B2 (ja) * 2014-07-17 2018-06-06 富士フイルム株式会社 イミダゾール化合物およびそれを含有するリポソーム
GB201614120D0 (en) * 2016-08-18 2016-10-05 Univ Of Kwazulu-Natal pH-responsive lipids
JP6462073B1 (ja) * 2017-09-04 2019-01-30 一丸ファルコス株式会社 ｐＨ感受性リポソームの製造方法
JP6399530B1 (ja) * 2017-09-04 2018-10-03 一丸ファルコス株式会社 ｐＨ感受性リポソーム
WO2019045097A1 (ja) * 2017-09-04 2019-03-07 一丸ファルコス株式会社 ｐＨ感受性リポソームおよびその製造方法
JP7406057B2 (ja) 2021-03-03 2023-12-27 東洋ビューティ株式会社 外用微粒子カプセル製剤及び皮膚外用剤
CN119552796A (zh) * 2024-11-29 2025-03-04 艾美行动生物制药有限公司 一种用于细胞培养添加物包载的pH敏感脂质体及制备方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8382004B2 (en) * 2001-04-04 2013-02-26 Graftech International Holdings Inc. Flexible graphite flooring heat spreader
JP5093547B2 (ja) * 2001-08-24 2012-12-12 日本ケミカルリサーチ株式会社 両イオン性脂質およびその用途
DE10207177A1 (de) 2002-02-19 2003-09-04 Novosom Ag Fakultativ kationische Lipide
CA2821167C (en) * 2004-05-03 2016-06-28 Merrimack Pharmaceuticals, Inc. Drug delivery liposomes containing anionic polyols or anionic sugars
US8658203B2 (en) 2004-05-03 2014-02-25 Merrimack Pharmaceuticals, Inc. Liposomes useful for drug delivery to the brain
AU2005300638A1 (en) 2004-11-05 2006-05-11 Novosom Ag Improvements in or relating to pharmaceutical compositions comprising an oligonucleotide as an active agent
US7838685B2 (en) 2005-04-27 2010-11-23 Shinji Takeoka Cationic amino acid type lipid
JP5571308B2 (ja) * 2005-09-15 2014-08-13 マリーナ バイオテック，インコーポレイテッド 両性リポソームにおけるまたはそれに関する改善
EP1764089A1 (en) 2005-09-15 2007-03-21 Novosom AG Serum stable liposomes comprising amphoter II lipid mixtures
EP1957044B1 (en) * 2005-12-01 2013-03-13 Pronai Therapeutics, Inc. Amphoteric liposome formulation
JP5253716B2 (ja) * 2006-02-09 2013-07-31 日本ケミカルリサーチ株式会社 ｐＨ応答性分子集合体
US8193246B2 (en) * 2006-12-19 2012-06-05 Marina Biotech, Inc. Lipids and lipid assemblies comprising transfection enhancer elements
US20080145413A1 (en) 2006-12-19 2008-06-19 Steffen Panzner Lipids and lipid assemblies comprising transfection enhancer elements
US8241647B2 (en) * 2007-05-17 2012-08-14 Waseda University Amphiphilic molecule, molecular assembly comprising the amphiphilic molecule, and use of the molecular assembly
AU2008309880B2 (en) * 2007-10-12 2014-07-10 Biontech Delivery Technologies Gmbh Amphoteric liposomes comprising neutral lipids
WO2009051712A1 (en) * 2007-10-15 2009-04-23 Pronai Therapeutics, Inc. Dnai amphoteric liposome formulation
US20100129430A1 (en) * 2008-11-24 2010-05-27 Stavroula Sofou Liposome drug carriers with ph-sensitivity

Also Published As

Publication number Publication date
EP2407158A1 (en) 2012-01-18
US20120064148A1 (en) 2012-03-15
JP5588619B2 (ja) 2014-09-10
US8871252B2 (en) 2014-10-28
WO2010104128A1 (ja) 2010-09-16
EP2407158A4 (en) 2013-09-04
JP2010209012A (ja) 2010-09-24

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