JP5587969B2 - 炎症及び疼痛の処置用の化合物 - Google Patents

炎症及び疼痛の処置用の化合物 Download PDF

Info

Publication number
JP5587969B2
JP5587969B2 JP2012500894A JP2012500894A JP5587969B2 JP 5587969 B2 JP5587969 B2 JP 5587969B2 JP 2012500894 A JP2012500894 A JP 2012500894A JP 2012500894 A JP2012500894 A JP 2012500894A JP 5587969 B2 JP5587969 B2 JP 5587969B2
Authority
JP
Japan
Prior art keywords
pain
compound
inflammation
pharmaceutical composition
acid ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2012500894A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012520888A (ja
JP2012520888A5 (enExample
Inventor
ピー．セント ローレント ジョセフ
Original Assignee
オラテック インダストリーズ リミティド ライアビリティ カンパニー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by オラテック インダストリーズ リミティド ライアビリティ カンパニー filed Critical オラテック インダストリーズ リミティド ライアビリティ カンパニー
Publication of JP2012520888A publication Critical patent/JP2012520888A/ja
Publication of JP2012520888A5 publication Critical patent/JP2012520888A5/ja
Application granted granted Critical
Publication of JP5587969B2 publication Critical patent/JP5587969B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/48—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2012500894A 2009-03-18 2010-03-16 炎症及び疼痛の処置用の化合物 Expired - Fee Related JP5587969B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16128509P 2009-03-18 2009-03-18
US61/161,285 2009-03-18
PCT/US2010/027501 WO2010107807A2 (en) 2009-03-18 2010-03-16 Compounds for treating inflammation and pain

Publications (3)

Publication Number Publication Date
JP2012520888A JP2012520888A (ja) 2012-09-10
JP2012520888A5 JP2012520888A5 (enExample) 2013-05-02
JP5587969B2 true JP5587969B2 (ja) 2014-09-10

Family

ID=42738194

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012500894A Expired - Fee Related JP5587969B2 (ja) 2009-03-18 2010-03-16 炎症及び疼痛の処置用の化合物

Country Status (11)

Country Link
US (1) US7851650B2 (enExample)
EP (1) EP2408740B1 (enExample)
JP (1) JP5587969B2 (enExample)
KR (1) KR20110128348A (enExample)
CN (1) CN102438983A (enExample)
AU (1) AU2010226794A1 (enExample)
BR (1) BRPI1014528A2 (enExample)
CA (1) CA2755678A1 (enExample)
MX (1) MX2011009709A (enExample)
RU (1) RU2520034C2 (enExample)
WO (1) WO2010107807A2 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2531026A4 (en) * 2010-02-04 2013-09-25 Novabay Pharmaceuticals Inc ANTIMICROBIAL FORMULATIONS ON POLYSACCHARID BASE
JP5932830B2 (ja) 2010-12-15 2016-06-08 オラテック セラピューティクス リミティド ライアビリティ カンパニー 炎症及び疼痛を処置するための３‐メタンスルホニルプロピオニトリル
US8802885B2 (en) 2012-02-27 2014-08-12 Olatec Industries Llc Process for preparing 3-methylsulfonylpropionitrile
US9481644B2 (en) 2012-06-05 2016-11-01 Olatec Therapeutics Llc Pharmaceutical composition comprising omega-(arylsulfonyl)alkylnitrile
CN104411303B (zh) * 2012-06-05 2017-09-05 欧拉泰克工业有限责任公司 用于治疗皮肤炎性疾病的方法
WO2013184708A1 (en) * 2012-06-05 2013-12-12 Olatec Industries Llc Pharmaceutical composition for treating inflammation and pain
AU2013271773B2 (en) * 2012-06-05 2018-03-08 Olatec Therapeutics Llc Pharmaceutical composition for treating inflammation and pain
MX368641B (es) 2012-06-11 2019-10-09 Olatec Ind Llc Compuestos para el tratamiento de inflamación y dolor.
WO2013188314A1 (en) * 2012-06-14 2013-12-19 Olatec Industries Llc Compounds for treating inflammation and pain
US9114122B2 (en) 2012-06-14 2015-08-25 Olatec Industries Llc Compounds for treating inflammation and pain
SE536581C2 (sv) 2012-07-24 2014-03-11 Rls Global Ab Ett kit för behandling av sår eller liknande och ett preparat och metoder därav
WO2015081188A1 (en) * 2013-11-27 2015-06-04 Olatec Industries Llc Pharmaceutical composition comprising omega-(arylsulfonyl)alkylnitrile
WO2025097064A1 (en) * 2023-11-03 2025-05-08 Mencanin Steve Novel ampoule for delivery of polymers for wound treatment

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3700729A1 (de) * 1987-01-13 1988-07-21 Boehringer Mannheim Gmbh Neue carbonsaeurederivate, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
PT668933E (pt) * 1992-11-19 2003-02-28 Anticancer Inc Utilizacao de metioninase como agente anti-tumor em qimioterapia anti-metionina
US6706670B2 (en) 1996-08-30 2004-03-16 Solutia, Inc. Water soluble metal working fluids
US6638701B1 (en) * 2002-12-17 2003-10-28 Eastman Kodak Company Photographic element containing a red dye-forming pyrazolotriazole coupler
RU2232752C1 (ru) * 2003-04-04 2004-07-20 Общество с ограниченной ответственностью "Поливит" Способ получения фосфата или сукцината 2-амино-4-метилтио-(s-оксо-s-имино)-масляной кислоты
US7423064B2 (en) 2004-09-24 2008-09-09 Olatec Industries, Llc Composition for treating bacterial, viral, fungal diseases, inflammation and pain
TWI386201B (zh) * 2005-01-25 2013-02-21 Novabay Pharmaceuticals Inc Ｎ-鹵化胺基酸、ｎ，ｎ-二鹵化胺基酸與其衍生物；以及使用其之組合物與方法
WO2006118196A1 (ja) * 2005-04-27 2006-11-09 Ajinomoto Co., Inc. Dpp4阻害剤及びその医薬用途
AU2006340367B2 (en) * 2006-03-20 2012-12-20 Olatec Industries Llc Composition for treating bacterial, viral, fungal diseases, inflammation and pain
US20080287866A1 (en) * 2007-01-31 2008-11-20 Adam Heller Methods and compositions for the treatment of pain

Also Published As

Publication number Publication date
BRPI1014528A2 (pt) 2016-04-05
EP2408740A4 (en) 2012-08-08
EP2408740A2 (en) 2012-01-25
JP2012520888A (ja) 2012-09-10
EP2408740B1 (en) 2013-11-20
MX2011009709A (es) 2011-12-06
CN102438983A (zh) 2012-05-02
US20100240756A1 (en) 2010-09-23
WO2010107807A3 (en) 2011-01-13
RU2011142008A (ru) 2013-04-27
CA2755678A1 (en) 2010-09-23
KR20110128348A (ko) 2011-11-29
US7851650B2 (en) 2010-12-14
AU2010226794A1 (en) 2011-10-27
RU2520034C2 (ru) 2014-06-20
WO2010107807A2 (en) 2010-09-23

Similar Documents

Publication Publication Date Title
JP5587969B2 (ja) 炎症及び疼痛の処置用の化合物
US11229620B2 (en) 3-methanesulfonylpropionitrile for treating inflammation and/or pain
JP2022542304A (ja) ブルシンゲル製剤及びその製造方法
US10143675B2 (en) Pharmaceutical composition for treating inflammation and pain
JP6360163B2 (ja) ３，４−ビス−ベンジルスルホニルブタンニトリル及びその医薬上の使用
US9440916B2 (en) 3, 4-bis-benzylsulfonylbutyronitrile and its pharmaceutical use
WO2013188214A1 (en) Compounds for treating inflammation and pain
EP2861228B1 (en) Compounds for treating inflammation and pain
CN105682460B (zh) 3,4-双-苄磺酰基丁腈及其药学用途
JP6457502B2 (ja) ３−ベンジルスルホニルプロピオニトリルの医薬上の使用
WO2015054008A1 (en) 4-methylsulfonyl-2-butenenitrile and its pharmaceutical use

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130313

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20130313

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20140624

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20140724

R150 Certificate of patent or registration of utility model

Ref document number: 5587969

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees