RU2520034C2 - Соединения для лечения воспаления - Google Patents

Соединения для лечения воспаления Download PDF

Info

Publication number
RU2520034C2
RU2520034C2 RU2011142008/04A RU2011142008A RU2520034C2 RU 2520034 C2 RU2520034 C2 RU 2520034C2 RU 2011142008/04 A RU2011142008/04 A RU 2011142008/04A RU 2011142008 A RU2011142008 A RU 2011142008A RU 2520034 C2 RU2520034 C2 RU 2520034C2
Authority
RU
Russia
Prior art keywords
inflammation
pain
solvent
ethyl acetate
methionine
Prior art date
Application number
RU2011142008/04A
Other languages
English (en)
Russian (ru)
Other versions
RU2011142008A (ru
Inventor
ЛОРЕН Джозеф П. СЕНТ
Original Assignee
ОЛАТЕК ИНДАСТРИЗ ЭлЭлСи
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ОЛАТЕК ИНДАСТРИЗ ЭлЭлСи filed Critical ОЛАТЕК ИНДАСТРИЗ ЭлЭлСи
Publication of RU2011142008A publication Critical patent/RU2011142008A/ru
Application granted granted Critical
Publication of RU2520034C2 publication Critical patent/RU2520034C2/ru

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/48—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
RU2011142008/04A 2009-03-18 2010-03-16 Соединения для лечения воспаления RU2520034C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16128509P 2009-03-18 2009-03-18
US61/161,285 2009-03-18
PCT/US2010/027501 WO2010107807A2 (en) 2009-03-18 2010-03-16 Compounds for treating inflammation and pain

Publications (2)

Publication Number Publication Date
RU2011142008A RU2011142008A (ru) 2013-04-27
RU2520034C2 true RU2520034C2 (ru) 2014-06-20

Family

ID=42738194

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2011142008/04A RU2520034C2 (ru) 2009-03-18 2010-03-16 Соединения для лечения воспаления

Country Status (11)

Country Link
US (1) US7851650B2 (enExample)
EP (1) EP2408740B1 (enExample)
JP (1) JP5587969B2 (enExample)
KR (1) KR20110128348A (enExample)
CN (1) CN102438983A (enExample)
AU (1) AU2010226794A1 (enExample)
BR (1) BRPI1014528A2 (enExample)
CA (1) CA2755678A1 (enExample)
MX (1) MX2011009709A (enExample)
RU (1) RU2520034C2 (enExample)
WO (1) WO2010107807A2 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2531026A4 (en) * 2010-02-04 2013-09-25 Novabay Pharmaceuticals Inc ANTIMICROBIAL FORMULATIONS ON POLYSACCHARID BASE
JP5932830B2 (ja) 2010-12-15 2016-06-08 オラテック セラピューティクス リミティド ライアビリティ カンパニー 炎症及び疼痛を処置するための３‐メタンスルホニルプロピオニトリル
US8802885B2 (en) 2012-02-27 2014-08-12 Olatec Industries Llc Process for preparing 3-methylsulfonylpropionitrile
US9481644B2 (en) 2012-06-05 2016-11-01 Olatec Therapeutics Llc Pharmaceutical composition comprising omega-(arylsulfonyl)alkylnitrile
CN104411303B (zh) * 2012-06-05 2017-09-05 欧拉泰克工业有限责任公司 用于治疗皮肤炎性疾病的方法
WO2013184708A1 (en) * 2012-06-05 2013-12-12 Olatec Industries Llc Pharmaceutical composition for treating inflammation and pain
AU2013271773B2 (en) * 2012-06-05 2018-03-08 Olatec Therapeutics Llc Pharmaceutical composition for treating inflammation and pain
MX368641B (es) 2012-06-11 2019-10-09 Olatec Ind Llc Compuestos para el tratamiento de inflamación y dolor.
WO2013188314A1 (en) * 2012-06-14 2013-12-19 Olatec Industries Llc Compounds for treating inflammation and pain
US9114122B2 (en) 2012-06-14 2015-08-25 Olatec Industries Llc Compounds for treating inflammation and pain
SE536581C2 (sv) 2012-07-24 2014-03-11 Rls Global Ab Ett kit för behandling av sår eller liknande och ett preparat och metoder därav
WO2015081188A1 (en) * 2013-11-27 2015-06-04 Olatec Industries Llc Pharmaceutical composition comprising omega-(arylsulfonyl)alkylnitrile
WO2025097064A1 (en) * 2023-11-03 2025-05-08 Mencanin Steve Novel ampoule for delivery of polymers for wound treatment

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5145611A (en) * 1987-01-13 1992-09-08 Boehringer Mannheim Gmbh Carboxylic acid derivatives, and pharmaceutical compositions containing them
RU2232752C1 (ru) * 2003-04-04 2004-07-20 Общество с ограниченной ответственностью "Поливит" Способ получения фосфата или сукцината 2-амино-4-метилтио-(s-оксо-s-имино)-масляной кислоты
US20060247209A1 (en) * 2005-01-25 2006-11-02 Ramin Najafi N-halogenated amino acids, N,N-dihalogenated amino acids and derivatives; compositions and methods of using them

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT668933E (pt) * 1992-11-19 2003-02-28 Anticancer Inc Utilizacao de metioninase como agente anti-tumor em qimioterapia anti-metionina
US6706670B2 (en) 1996-08-30 2004-03-16 Solutia, Inc. Water soluble metal working fluids
US6638701B1 (en) * 2002-12-17 2003-10-28 Eastman Kodak Company Photographic element containing a red dye-forming pyrazolotriazole coupler
US7423064B2 (en) 2004-09-24 2008-09-09 Olatec Industries, Llc Composition for treating bacterial, viral, fungal diseases, inflammation and pain
WO2006118196A1 (ja) * 2005-04-27 2006-11-09 Ajinomoto Co., Inc. Dpp4阻害剤及びその医薬用途
AU2006340367B2 (en) * 2006-03-20 2012-12-20 Olatec Industries Llc Composition for treating bacterial, viral, fungal diseases, inflammation and pain
US20080287866A1 (en) * 2007-01-31 2008-11-20 Adam Heller Methods and compositions for the treatment of pain

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5145611A (en) * 1987-01-13 1992-09-08 Boehringer Mannheim Gmbh Carboxylic acid derivatives, and pharmaceutical compositions containing them
RU2232752C1 (ru) * 2003-04-04 2004-07-20 Общество с ограниченной ответственностью "Поливит" Способ получения фосфата или сукцината 2-амино-4-метилтио-(s-оксо-s-имино)-масляной кислоты
US20060247209A1 (en) * 2005-01-25 2006-11-02 Ramin Najafi N-halogenated amino acids, N,N-dihalogenated amino acids and derivatives; compositions and methods of using them

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ABO-GHALIA M. et al, International Journal of Peptide & Protein Research, vol.32, no. 3, 1988, p.p. 208-222. *

Also Published As

Publication number Publication date
BRPI1014528A2 (pt) 2016-04-05
EP2408740A4 (en) 2012-08-08
EP2408740A2 (en) 2012-01-25
JP2012520888A (ja) 2012-09-10
EP2408740B1 (en) 2013-11-20
JP5587969B2 (ja) 2014-09-10
MX2011009709A (es) 2011-12-06
CN102438983A (zh) 2012-05-02
US20100240756A1 (en) 2010-09-23
WO2010107807A3 (en) 2011-01-13
RU2011142008A (ru) 2013-04-27
CA2755678A1 (en) 2010-09-23
KR20110128348A (ko) 2011-11-29
US7851650B2 (en) 2010-12-14
AU2010226794A1 (en) 2011-10-27
WO2010107807A2 (en) 2010-09-23

Similar Documents

Publication Publication Date Title
RU2520034C2 (ru) Соединения для лечения воспаления
KR101849813B1 (ko) 염증 및 통증 치료용 3-메탄술포닐프로피오니트릴
RU2724053C2 (ru) Фармацевтические составы для местного применения для лечения связанных с воспалением состояний
US11491122B2 (en) Use of a combination of Adelmidrol and hyaluronic acid in the treatment of pain caused by osteoarthritis and epithelial dysfunctions
EP3048886B1 (en) 3, 4-bis-benzylsulfonylbutanenitrile and its pharmaceutical use
Schnetler et al. Lipid composition of human meibum
HU227496B1 (en) Transdermal pharmaceutical composition containing aspirine for the treatment of sclerosis
RU2403035C2 (ru) Композиция для лечения бактериальных, вирусных, грибковых заболеваний, воспаления и боли
HK1217913B (en) Use of adelmidrol in the treatment of epithelial dysfunctions
WO2000053174A1 (en) Modulation of protein expression using carbocyclic aryl alkenoic acid derivatives
BR102015016445B1 (pt) Uso do adelmidrol

Legal Events

Date Code Title Description
MM4A The patent is invalid due to non-payment of fees

Effective date: 20190317