CN102438983A - 用于治疗炎症和疼痛的化合物 - Google Patents
用于治疗炎症和疼痛的化合物 Download PDFInfo
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- CN102438983A CN102438983A CN2010800216665A CN201080021666A CN102438983A CN 102438983 A CN102438983 A CN 102438983A CN 2010800216665 A CN2010800216665 A CN 2010800216665A CN 201080021666 A CN201080021666 A CN 201080021666A CN 102438983 A CN102438983 A CN 102438983A
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- pain
- compound
- inflammation
- lactate
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Classifications
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C315/00—Preparation of sulfones; Preparation of sulfoxides
- C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
- C07C317/48—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16128509P | 2009-03-18 | 2009-03-18 | |
| US61/161,285 | 2009-03-18 | ||
| PCT/US2010/027501 WO2010107807A2 (en) | 2009-03-18 | 2010-03-16 | Compounds for treating inflammation and pain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102438983A true CN102438983A (zh) | 2012-05-02 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010800216665A Pending CN102438983A (zh) | 2009-03-18 | 2010-03-16 | 用于治疗炎症和疼痛的化合物 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7851650B2 (enExample) |
| EP (1) | EP2408740B1 (enExample) |
| JP (1) | JP5587969B2 (enExample) |
| KR (1) | KR20110128348A (enExample) |
| CN (1) | CN102438983A (enExample) |
| AU (1) | AU2010226794A1 (enExample) |
| BR (1) | BRPI1014528A2 (enExample) |
| CA (1) | CA2755678A1 (enExample) |
| MX (1) | MX2011009709A (enExample) |
| RU (1) | RU2520034C2 (enExample) |
| WO (1) | WO2010107807A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104349772A (zh) * | 2012-06-11 | 2015-02-11 | 欧拉泰克工业有限责任公司 | 用于治疗炎症和疼痛的化合物 |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2531026A4 (en) * | 2010-02-04 | 2013-09-25 | Novabay Pharmaceuticals Inc | ANTIMICROBIAL FORMULATIONS ON POLYSACCHARID BASE |
| JP5932830B2 (ja) | 2010-12-15 | 2016-06-08 | オラテック セラピューティクス リミティド ライアビリティ カンパニー | 炎症及び疼痛を処置するための３‐メタンスルホニルプロピオニトリル |
| US8802885B2 (en) | 2012-02-27 | 2014-08-12 | Olatec Industries Llc | Process for preparing 3-methylsulfonylpropionitrile |
| US9481644B2 (en) | 2012-06-05 | 2016-11-01 | Olatec Therapeutics Llc | Pharmaceutical composition comprising omega-(arylsulfonyl)alkylnitrile |
| CN104411303B (zh) * | 2012-06-05 | 2017-09-05 | 欧拉泰克工业有限责任公司 | 用于治疗皮肤炎性疾病的方法 |
| WO2013184708A1 (en) * | 2012-06-05 | 2013-12-12 | Olatec Industries Llc | Pharmaceutical composition for treating inflammation and pain |
| AU2013271773B2 (en) * | 2012-06-05 | 2018-03-08 | Olatec Therapeutics Llc | Pharmaceutical composition for treating inflammation and pain |
| WO2013188314A1 (en) * | 2012-06-14 | 2013-12-19 | Olatec Industries Llc | Compounds for treating inflammation and pain |
| US9114122B2 (en) | 2012-06-14 | 2015-08-25 | Olatec Industries Llc | Compounds for treating inflammation and pain |
| SE536581C2 (sv) | 2012-07-24 | 2014-03-11 | Rls Global Ab | Ett kit för behandling av sår eller liknande och ett preparat och metoder därav |
| WO2015081188A1 (en) * | 2013-11-27 | 2015-06-04 | Olatec Industries Llc | Pharmaceutical composition comprising omega-(arylsulfonyl)alkylnitrile |
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- 2010-03-16 WO PCT/US2010/027501 patent/WO2010107807A2/en not_active Ceased
- 2010-03-16 KR KR1020117024374A patent/KR20110128348A/ko not_active Withdrawn
- 2010-03-16 RU RU2011142008/04A patent/RU2520034C2/ru not_active IP Right Cessation
- 2010-03-16 CA CA2755678A patent/CA2755678A1/en not_active Abandoned
- 2010-03-16 CN CN2010800216665A patent/CN102438983A/zh active Pending
- 2010-03-16 EP EP10753988.4A patent/EP2408740B1/en not_active Not-in-force
- 2010-03-16 MX MX2011009709A patent/MX2011009709A/es active IP Right Grant
- 2010-03-16 BR BRPI1014528A patent/BRPI1014528A2/pt not_active IP Right Cessation
- 2010-03-16 AU AU2010226794A patent/AU2010226794A1/en not_active Abandoned
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Also Published As
| Publication number | Publication date |
|---|---|
| BRPI1014528A2 (pt) | 2016-04-05 |
| EP2408740A4 (en) | 2012-08-08 |
| EP2408740A2 (en) | 2012-01-25 |
| JP2012520888A (ja) | 2012-09-10 |
| EP2408740B1 (en) | 2013-11-20 |
| JP5587969B2 (ja) | 2014-09-10 |
| MX2011009709A (es) | 2011-12-06 |
| US20100240756A1 (en) | 2010-09-23 |
| WO2010107807A3 (en) | 2011-01-13 |
| RU2011142008A (ru) | 2013-04-27 |
| CA2755678A1 (en) | 2010-09-23 |
| KR20110128348A (ko) | 2011-11-29 |
| US7851650B2 (en) | 2010-12-14 |
| AU2010226794A1 (en) | 2011-10-27 |
| RU2520034C2 (ru) | 2014-06-20 |
| WO2010107807A2 (en) | 2010-09-23 |
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