KR20110128348A - 염증 및 통증 치료용 화합물 - Google Patents

염증 및 통증 치료용 화합물 Download PDF

Info

Publication number
KR20110128348A
KR20110128348A KR1020117024374A KR20117024374A KR20110128348A KR 20110128348 A KR20110128348 A KR 20110128348A KR 1020117024374 A KR1020117024374 A KR 1020117024374A KR 20117024374 A KR20117024374 A KR 20117024374A KR 20110128348 A KR20110128348 A KR 20110128348A
Authority
KR
South Korea
Prior art keywords
pain
inflammation
compound
lactate
methylsulfonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020117024374A
Other languages
English (en)
Korean (ko)
Inventor
로렌 조셉 피 세인트
Original Assignee
오라텍 인더스트리즈 엘엘씨
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 오라텍 인더스트리즈 엘엘씨 filed Critical 오라텍 인더스트리즈 엘엘씨
Publication of KR20110128348A publication Critical patent/KR20110128348A/ko
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00Preparation of sulfones; Preparation of sulfoxides
    • C07C315/02Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/44Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/48Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020117024374A 2009-03-18 2010-03-16 염증 및 통증 치료용 화합물 Withdrawn KR20110128348A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16128509P 2009-03-18 2009-03-18
US61/161,285 2009-03-18

Publications (1)

Publication Number Publication Date
KR20110128348A true KR20110128348A (ko) 2011-11-29

Family

ID=42738194

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020117024374A Withdrawn KR20110128348A (ko) 2009-03-18 2010-03-16 염증 및 통증 치료용 화합물

Country Status (11)

Country Link
US (1) US7851650B2 (enExample)
EP (1) EP2408740B1 (enExample)
JP (1) JP5587969B2 (enExample)
KR (1) KR20110128348A (enExample)
CN (1) CN102438983A (enExample)
AU (1) AU2010226794A1 (enExample)
BR (1) BRPI1014528A2 (enExample)
CA (1) CA2755678A1 (enExample)
MX (1) MX2011009709A (enExample)
RU (1) RU2520034C2 (enExample)
WO (1) WO2010107807A2 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011097324A1 (en) * 2010-02-04 2011-08-11 Novabay Pharmaceuticals, Inc. Polysaccharide based antimicrobial formulations
BR112013014583A2 (pt) 2010-12-15 2016-09-20 Olatec Ind Llc composição farmacêutica, e, métodos para o tratamento de inflamação, para o tratamento da dor, e para preparar 3-metanossulfonilpropionitrila
JP6151723B2 (ja) 2012-02-27 2017-06-21 オラテック セラピューティクス リミティド ライアビリティ カンパニー 3−メチルスルホニルプロピオニトリルを調製するプロセス
WO2013184703A1 (en) 2012-06-05 2013-12-12 Olatec Industries Llc Pharmaceutical composition for treating inflammation and pain
CN104363902A (zh) * 2012-06-05 2015-02-18 欧拉泰克工业有限责任公司 用于治疗炎症和疼痛的药物组合物
CN104411303B (zh) * 2012-06-05 2017-09-05 欧拉泰克工业有限责任公司 用于治疗皮肤炎性疾病的方法
US9481644B2 (en) 2012-06-05 2016-11-01 Olatec Therapeutics Llc Pharmaceutical composition comprising omega-(arylsulfonyl)alkylnitrile
BR112014030547A2 (pt) * 2012-06-11 2017-06-27 Olatec Ind Llc composição farmacêutica
US9114122B2 (en) 2012-06-14 2015-08-25 Olatec Industries Llc Compounds for treating inflammation and pain
CN104394860B (zh) * 2012-06-14 2017-04-26 欧拉泰克工业有限责任公司 用于治疗炎症和疼痛的化合物
SE536581C2 (sv) 2012-07-24 2014-03-11 Rls Global Ab Ett kit för behandling av sår eller liknande och ett preparat och metoder därav
WO2015081188A1 (en) * 2013-11-27 2015-06-04 Olatec Industries Llc Pharmaceutical composition comprising omega-(arylsulfonyl)alkylnitrile
WO2025097064A1 (en) * 2023-11-03 2025-05-08 Mencanin Steve Novel ampoule for delivery of polymers for wound treatment

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3700729A1 (de) * 1987-01-13 1988-07-21 Boehringer Mannheim Gmbh Neue carbonsaeurederivate, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
DE69332357T2 (de) * 1992-11-19 2003-06-18 Anticancer Inc., San Diego Verwendung von methioninase als antitumormittel in der antimethionin-chemotherapie
PL331923A1 (en) 1996-08-30 1999-08-16 Solutia Inc Novel water-soluble fluids for use in metal machining operations
US6638701B1 (en) * 2002-12-17 2003-10-28 Eastman Kodak Company Photographic element containing a red dye-forming pyrazolotriazole coupler
RU2232752C1 (ru) * 2003-04-04 2004-07-20 Общество с ограниченной ответственностью "Поливит" Способ получения фосфата или сукцината 2-амино-4-метилтио-(s-оксо-s-имино)-масляной кислоты
US7423064B2 (en) 2004-09-24 2008-09-09 Olatec Industries, Llc Composition for treating bacterial, viral, fungal diseases, inflammation and pain
TWI386201B (zh) * 2005-01-25 2013-02-21 Novabay Pharmaceuticals Inc N-鹵化胺基酸、n,n-二鹵化胺基酸與其衍生物;以及使用其之組合物與方法
WO2006118196A1 (ja) * 2005-04-27 2006-11-09 Ajinomoto Co., Inc. Dpp4阻害剤及びその医薬用途
WO2007108807A1 (en) * 2006-03-20 2007-09-27 Olatec Industries Llc Composition for treating bacterial, viral, fungal diseases, inflammation and pain
EP2120555A1 (en) * 2007-01-31 2009-11-25 Adam Heller Methods and compositions for the treatment of pain

Also Published As

Publication number Publication date
MX2011009709A (es) 2011-12-06
RU2011142008A (ru) 2013-04-27
US7851650B2 (en) 2010-12-14
CN102438983A (zh) 2012-05-02
US20100240756A1 (en) 2010-09-23
WO2010107807A3 (en) 2011-01-13
CA2755678A1 (en) 2010-09-23
RU2520034C2 (ru) 2014-06-20
WO2010107807A2 (en) 2010-09-23
BRPI1014528A2 (pt) 2016-04-05
EP2408740B1 (en) 2013-11-20
JP2012520888A (ja) 2012-09-10
EP2408740A4 (en) 2012-08-08
JP5587969B2 (ja) 2014-09-10
EP2408740A2 (en) 2012-01-25
AU2010226794A1 (en) 2011-10-27

Similar Documents

Publication Publication Date Title
US7851650B2 (en) Compounds for treating inflammation and pain
KR101849813B1 (ko) 염증 및 통증 치료용 3-메탄술포닐프로피오니트릴
US11491122B2 (en) Use of a combination of Adelmidrol and hyaluronic acid in the treatment of pain caused by osteoarthritis and epithelial dysfunctions
US20230242558A1 (en) Nicotinate and nicotinamide riboside-based compounds and derivatives thereof
EP3048886B1 (en) 3, 4-bis-benzylsulfonylbutanenitrile and its pharmaceutical use
WO2013188214A1 (en) Compounds for treating inflammation and pain
EP2861228B1 (en) Compounds for treating inflammation and pain
Cope et al. The degradation of salbutamol in ethanolic solutions
WO2015054008A1 (en) 4-methylsulfonyl-2-butenenitrile and its pharmaceutical use
HK1217913B (en) Use of adelmidrol in the treatment of epithelial dysfunctions

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20111017

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid