JP5567837B2 - Ａｘｌインヒビターとして有用なＮ３−ヘテロアリール置換トリアゾールおよびＮ５−ヘテロアリール置換トリアゾール - Google Patents

Ａｘｌインヒビターとして有用なＮ３−ヘテロアリール置換トリアゾールおよびＮ５−ヘテロアリール置換トリアゾール Download PDF

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JP5567837B2
JP5567837B2 JP2009544313A JP2009544313A JP5567837B2 JP 5567837 B2 JP5567837 B2 JP 5567837B2 JP 2009544313 A JP2009544313 A JP 2009544313A JP 2009544313 A JP2009544313 A JP 2009544313A JP 5567837 B2 JP5567837 B2 JP 5567837B2
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optionally substituted
triazole
diamine
pyrimidin
methylthieno
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JP2010514809A5 (OSRAM
JP2010514809A (ja
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デーン ゴフ，
チン チャン，
ラジンダー シン，
サッシャ ホーランド，
チアシン ユー，
ティロ ヘックロッド，
ピンユー ディン，
ジョアン リトバク，
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ライジェル ファーマシューティカルズ， インコーポレイテッド
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    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
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    • C07D495/04—Ortho-condensed systems
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    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Reproductive Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
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  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP2009544313A 2006-12-29 2007-12-28 Ａｘｌインヒビターとして有用なＮ３−ヘテロアリール置換トリアゾールおよびＮ５−ヘテロアリール置換トリアゾール Expired - Fee Related JP5567837B2 (ja)

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US88287506P 2006-12-29 2006-12-29
US60/882,875 2006-12-29
US97544307P 2007-09-26 2007-09-26
US60/975,443 2007-09-26
PCT/US2007/089153 WO2008083354A1 (en) 2006-12-29 2007-12-28 N3-heteroaryl substituted triazoles and n5-heteroaryl substituted triazoles useful as axl inhibitors

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JP2010514809A JP2010514809A (ja) 2010-05-06
JP2010514809A5 JP2010514809A5 (OSRAM) 2013-09-12
JP5567837B2 true JP5567837B2 (ja) 2014-08-06

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JP2014024758A Expired - Fee Related JP5890445B2 (ja) 2006-12-29 2014-02-12 Ａｘｌインヒビターとして有用なＮ３−ヘテロアリール置換トリアゾールおよびＮ５−ヘテロアリール置換トリアゾール

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US (2) US9650391B2 (OSRAM)
EP (2) EP2074115B1 (OSRAM)
JP (2) JP5567837B2 (OSRAM)
CN (1) CN101622248B (OSRAM)
AU (1) AU2007342005A1 (OSRAM)
CA (1) CA2710046C (OSRAM)
ES (2) ES2672172T3 (OSRAM)
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