JP5559043B2 - 新規ヘテロ環化合物およびその使用 - Google Patents
新規ヘテロ環化合物およびその使用 Download PDFInfo
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- JP5559043B2 JP5559043B2 JP2010511212A JP2010511212A JP5559043B2 JP 5559043 B2 JP5559043 B2 JP 5559043B2 JP 2010511212 A JP2010511212 A JP 2010511212A JP 2010511212 A JP2010511212 A JP 2010511212A JP 5559043 B2 JP5559043 B2 JP 5559043B2
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Classifications
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- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A61P25/00—Drugs for disorders of the nervous system
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| TW201103904A (en) * | 2009-06-11 | 2011-02-01 | Hoffmann La Roche | Janus kinase inhibitor compounds and methods |
| WO2011016861A2 (en) | 2009-08-05 | 2011-02-10 | Intra-Cellular Therapies, Inc. | Novel regulatory proteins and inhibitors |
| CN107652269A (zh) * | 2016-07-26 | 2018-02-02 | 江苏豪森药业集团有限公司 | 甲磺酸氟马替尼中间体纯化方法 |
| JP2022523562A (ja) * | 2019-03-05 | 2022-04-25 | ホンイー アンド アソシエイツ エルエルシー | 神経変性疾患および癌の治療のための化合物 |
| CN116789643B (zh) * | 2023-06-25 | 2025-05-06 | 海南医学院 | 一种2-氨基嘧啶类化合物及其制备方法和应用 |
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| GB0215676D0 (en) | 2002-07-05 | 2002-08-14 | Novartis Ag | Organic compounds |
| US7279576B2 (en) * | 2002-12-31 | 2007-10-09 | Deciphera Pharmaceuticals, Llc | Anti-cancer medicaments |
| CN1805748B (zh) | 2003-06-13 | 2010-05-26 | 诺瓦提斯公司 | 作为raf激酶抑制剂的2-氨基嘧啶衍生物 |
| GB0325031D0 (en) * | 2003-10-27 | 2003-12-03 | Novartis Ag | Organic compounds |
| DE602005023587D1 (de) | 2004-01-21 | 2010-10-28 | Univ Emory | Zusammensetzungen und verwendung von tyrosinkinase-hemmern zur behandlung von pathogenen infektionen |
| CA2578122A1 (en) * | 2004-08-27 | 2006-03-02 | Gpc Biotech Ag | Pyrimidine derivatives |
| CN1939910A (zh) * | 2004-12-31 | 2007-04-04 | 孙飘扬 | 氨基嘧啶类化合物及其盐和其制备方法与药物用途 |
| CN1972917B (zh) * | 2004-12-31 | 2010-08-25 | 孙飘扬 | 氨基嘧啶类化合物及其盐和其制备方法与药物用途 |
| WO2008153974A1 (en) * | 2007-06-07 | 2008-12-18 | Intra-Cellular Therapies, Inc. | Novel heterocycle compounds and uses thereof |
| US8367686B2 (en) * | 2007-06-07 | 2013-02-05 | Intra-Cellular Therapies, Inc. | Heterocycle compounds and uses thereof |
| HUE027027T2 (en) * | 2008-11-13 | 2016-08-29 | Modgene Llc | Reduction of amyloid beta load in non-brain tissue |
-
2008
- 2008-06-06 WO PCT/US2008/007167 patent/WO2008153974A1/en not_active Ceased
- 2008-06-06 EP EP08768240.7A patent/EP2166860B1/en not_active Not-in-force
- 2008-06-06 JP JP2010511212A patent/JP5559043B2/ja not_active Expired - Fee Related
- 2008-06-06 US US12/663,224 patent/US9062023B2/en active Active
- 2008-06-06 ES ES08768240.7T patent/ES2607794T3/es active Active
-
2014
- 2014-06-05 JP JP2014116664A patent/JP6017496B2/ja not_active Expired - Fee Related
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2015
- 2015-06-22 US US14/745,806 patent/US20160075683A1/en not_active Abandoned
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014193912A (ja) * | 2007-06-07 | 2014-10-09 | Intra-Cellular Therapies Inc | 新規ヘテロ環化合物およびその使用 |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2607794T3 (es) | 2017-04-04 |
| WO2008153974A1 (en) | 2008-12-18 |
| US20160075683A1 (en) | 2016-03-17 |
| JP2010529132A (ja) | 2010-08-26 |
| JP6017496B2 (ja) | 2016-11-02 |
| EP2166860A1 (en) | 2010-03-31 |
| EP2166860A4 (en) | 2010-06-02 |
| JP2014193912A (ja) | 2014-10-09 |
| US20100184778A1 (en) | 2010-07-22 |
| US9062023B2 (en) | 2015-06-23 |
| EP2166860B1 (en) | 2016-09-21 |
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