JP5551584B2 - キメラｐｕｆａポリケチドシンターゼシステムおよびその使用 - Google Patents

キメラｐｕｆａポリケチドシンターゼシステムおよびその使用 Download PDF

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JP5551584B2
JP5551584B2 JP2010508603A JP2010508603A JP5551584B2 JP 5551584 B2 JP5551584 B2 JP 5551584B2 JP 2010508603 A JP2010508603 A JP 2010508603A JP 2010508603 A JP2010508603 A JP 2010508603A JP 5551584 B2 JP5551584 B2 JP 5551584B2
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pufa pks
seq
pks system
nucleic acid
pufa
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JP2010527244A (ja
JP2010527244A5 (enExample
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クレイグ エイ． ウェバー
ロス ザークル
ダニエル エイチ． ドーアティ
ジェイムズ ジー． メッツ
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DSM IP Assets BV
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    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434—Docosahexenoic acids [DHA]
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Oil, Petroleum & Natural Gas (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Neurology (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
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JP2010508603A 2007-05-16 2008-05-16 キメラｐｕｆａポリケチドシンターゼシステムおよびその使用 Expired - Fee Related JP5551584B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/749,686 US8003772B2 (en) 1999-01-14 2007-05-16 Chimeric PUFA polyketide synthase systems and uses thereof
US11/749,686 2007-05-16
PCT/US2008/063835 WO2008144473A2 (en) 2007-05-16 2008-05-16 Chimeric pufa polyketide synthase systems and uses thereof

Publications (3)

Publication Number Publication Date
JP2010527244A JP2010527244A (ja) 2010-08-12
JP2010527244A5 JP2010527244A5 (enExample) 2011-06-30
JP5551584B2 true JP5551584B2 (ja) 2014-07-16

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JP2010508603A Expired - Fee Related JP5551584B2 (ja) 2007-05-16 2008-05-16 キメラｐｕｆａポリケチドシンターゼシステムおよびその使用

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Country Link
US (3) US8003772B2 (enExample)
EP (1) EP2160470B1 (enExample)
JP (1) JP5551584B2 (enExample)
KR (1) KR101539470B1 (enExample)
CN (1) CN101849014B (enExample)
AU (1) AU2008254837B2 (enExample)
BR (1) BRPI0810302A2 (enExample)
CA (1) CA2687523C (enExample)
ES (1) ES2467918T3 (enExample)
IL (1) IL202131A (enExample)
MX (1) MX2009012395A (enExample)
WO (1) WO2008144473A2 (enExample)

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US8003772B2 (en) * 1999-01-14 2011-08-23 Martek Biosciences Corporation Chimeric PUFA polyketide synthase systems and uses thereof
US7211418B2 (en) 1999-01-14 2007-05-01 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
US7247461B2 (en) * 1999-01-14 2007-07-24 Martek Biosciences Corporation Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof
US20070244192A1 (en) * 1999-01-14 2007-10-18 Martek Biosciences Corporation Plant seed oils containing polyunsaturated fatty acids
US7217856B2 (en) * 1999-01-14 2007-05-15 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
TWI324181B (en) 2001-04-16 2010-05-01 Martek Biosciences Corp Product and process for transformation of thraustochytriales microorganisms
US7807849B2 (en) 2004-04-22 2010-10-05 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
CA3023314C (en) 2004-04-22 2019-12-10 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
MX339812B (es) * 2006-03-15 2016-06-08 Dsm Ip Assets B V * Produccion de acido graso poli-insaturado en organismos heterologos usando sistemas de sintasa de policetido pufa.
AU2007291937B2 (en) 2006-08-29 2014-05-15 Commonwealth Scientific And Industrial Research Organisation Synthesis of fatty acids
CN102076355B (zh) 2008-04-29 2014-05-07 Abbvie公司 双重可变结构域免疫球蛋白及其用途
TW201008580A (en) 2008-06-03 2010-03-01 Abbott Lab Dual variable domain immunoglobulin and uses thereof
NO2358882T3 (enExample) 2008-11-18 2017-12-23
TWI548648B (zh) * 2009-03-16 2016-09-11 Ｄｓｍ智慧財產有限公司 於網黏菌門微生物中生產蛋白質之技術
CA2755639C (en) * 2009-03-19 2018-09-25 Martek Biosciences Corporation Polyunsaturated fatty acid synthase nucleic acid molecules and polypeptides, compositions, and methods of making and uses thereof
US8207363B2 (en) 2009-03-19 2012-06-26 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
CA3121944A1 (en) * 2009-09-24 2011-03-31 Kyushu University, National University Corporation Method for transforming stramenopiles
CA3153553A1 (en) * 2009-12-28 2011-07-28 Sanofi Vaccine Technologies, S.A.S. Methods of producing heterologous proteins comprising membrane domains in microalgal extracellular bodies
KR20120101572A (ko) 2009-12-28 2012-09-13 메리얼 리미티드 재조합 ｎｄｖ 항원 및 이의 용도
CN103068984B (zh) * 2009-12-28 2017-12-01 Dsm Ip资产公司 微藻中血凝素‑神经氨酸酶蛋白的生产
CN107858297A (zh) 2009-12-28 2018-03-30 Dsm Ip资产公司 在蔗糖上生长的重组破囊壶菌和其组合物、制备方法及用途
WO2011090730A1 (en) * 2009-12-28 2011-07-28 Martek Biosciences Corporation Recombinant thraustochytrids that grow on xylose, and compositions, methods of making, and uses thereof
CA2993690C (en) * 2010-01-19 2022-03-22 Dsm Ip Assets B.V. Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
AU2011224188B2 (en) 2010-03-12 2015-01-22 Boehringer Ingelheim Animal Health USA Inc. Bluetongue virus recombinant vaccines and uses thereof
TW201144442A (en) 2010-05-17 2011-12-16 Dow Agrosciences Llc Production of DHA and other LC-PUFAs in plants
US11236351B2 (en) * 2010-05-17 2022-02-01 Dow Agrosciences Llc Production of DHA and other LC PUFAs in plants
UY33492A (es) 2010-07-09 2012-01-31 Abbott Lab Inmunoglobulinas con dominio variable dual y usos de las mismas
PE20131412A1 (es) 2010-08-03 2014-01-19 Abbvie Inc Inmunoglobulinas con dominio variable dual y usos de las mismas
KR101964168B1 (ko) * 2010-10-01 2019-04-01 고쿠리쓰다이가쿠호진 규슈다이가쿠 스트라메노파일의 형질 전환 방법
MX338479B (es) * 2011-03-07 2016-04-19 Dsm Nutritional Products Ag Microorganismos thraustochytrid modificados.
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