AU2008254837B2 - Chimeric PUFA polyketide synthase systems and uses thereof - Google Patents

Chimeric PUFA polyketide synthase systems and uses thereof Download PDF

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Publication number
AU2008254837B2
AU2008254837B2 AU2008254837A AU2008254837A AU2008254837B2 AU 2008254837 B2 AU2008254837 B2 AU 2008254837B2 AU 2008254837 A AU2008254837 A AU 2008254837A AU 2008254837 A AU2008254837 A AU 2008254837A AU 2008254837 B2 AU2008254837 B2 AU 2008254837B2
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seq
pufa pks
pks system
nucleic acid
domain
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AU2008254837A
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AU2008254837A1 (en
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Daniel H. Doherty
James G. Metz
Craig A. Weaver
Ross Zirkle
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DSM IP Assets BV
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434—Docosahexenoic acids [DHA]
    • A—HUMAN NECESSITIES
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    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
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    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
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  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
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AU2008254837A 2007-05-16 2008-05-16 Chimeric PUFA polyketide synthase systems and uses thereof Ceased AU2008254837B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/749,686 2007-05-16
US11/749,686 US8003772B2 (en) 1999-01-14 2007-05-16 Chimeric PUFA polyketide synthase systems and uses thereof
PCT/US2008/063835 WO2008144473A2 (en) 2007-05-16 2008-05-16 Chimeric pufa polyketide synthase systems and uses thereof

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AU2008254837A1 AU2008254837A1 (en) 2008-11-27
AU2008254837B2 true AU2008254837B2 (en) 2013-09-12

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AU2008254837A Ceased AU2008254837B2 (en) 2007-05-16 2008-05-16 Chimeric PUFA polyketide synthase systems and uses thereof

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US (3) US8003772B2 (enExample)
EP (1) EP2160470B1 (enExample)
JP (1) JP5551584B2 (enExample)
KR (1) KR101539470B1 (enExample)
CN (1) CN101849014B (enExample)
AU (1) AU2008254837B2 (enExample)
BR (1) BRPI0810302A2 (enExample)
CA (1) CA2687523C (enExample)
ES (1) ES2467918T3 (enExample)
IL (1) IL202131A (enExample)
MX (1) MX2009012395A (enExample)
WO (1) WO2008144473A2 (enExample)

Cited By (1)

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US20070244192A1 (en) * 1999-01-14 2007-10-18 Martek Biosciences Corporation Plant seed oils containing polyunsaturated fatty acids
US7247461B2 (en) * 1999-01-14 2007-07-24 Martek Biosciences Corporation Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof
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TWI377253B (en) 2001-04-16 2012-11-21 Martek Biosciences Corp Product and process for transformation of thraustochytriales microorganisms
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CA3056110C (en) 2004-04-22 2020-07-14 Surinder Pal Singh Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
WO2007106903A2 (en) 2006-03-15 2007-09-20 Martek Biosciences Corporation Polyunsaturated fatty acid production in heterologous organisms using pufa polyketide synthase systems
RU2009111266A (ru) 2006-08-29 2010-10-10 Коммонвелт Сайентифик энд Индастриал Рисерч Организейшн (AU) Синтез жирных кислот
EP2282769A4 (en) 2008-04-29 2012-04-25 Abbott Lab DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND ITS USES
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DK2358882T3 (da) 2008-11-18 2017-11-06 Commw Scient Ind Res Org Enzymer og fremgangsmåder til fremstilling af omega-3 fedtsyrer
US8207363B2 (en) 2009-03-19 2012-06-26 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
ES2717102T3 (es) 2009-03-19 2019-06-19 Dsm Ip Assets Bv Moléculas de ácido nucleico de ácido graso poliinsaturado sintasas, y polipéptidos, composiciones y métodos de preparación y usos de los mismos
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CN102906270B (zh) * 2009-12-28 2016-06-22 Dsmip资产公司 在木糖上生长的重组破囊壶菌和其组合物、制备方法及用途
EA030095B1 (ru) * 2009-12-28 2018-06-29 ДиЭсЭм АйПи АССЕТС Б.В. Получение белка гемагглютинин-нейраминидазы в микроводорослях
EP3213766A1 (en) 2009-12-28 2017-09-06 Merial Ltd. Recombinant ndv antigen and uses thereof
EP2519625B1 (en) 2009-12-28 2018-09-26 DSM IP Assets B.V. Recombinant thraustochytrids that grow on sucrose, and compositions, methods of making, and uses thereof
CA2993690C (en) 2010-01-19 2022-03-22 Dsm Ip Assets B.V. Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
WO2011112945A2 (en) 2010-03-12 2011-09-15 Merial Limited Foot and mouth disease virus recombinant vaccines and uses thereof
US11236351B2 (en) * 2010-05-17 2022-02-01 Dow Agrosciences Llc Production of DHA and other LC PUFAs in plants
TW201144442A (en) * 2010-05-17 2011-12-16 Dow Agrosciences Llc Production of DHA and other LC-PUFAs in plants
UY33492A (es) 2010-07-09 2012-01-31 Abbott Lab Inmunoglobulinas con dominio variable dual y usos de las mismas
KR20130100118A (ko) 2010-08-03 2013-09-09 아비에 인코포레이티드 이원 가변 도메인 면역글로불린 및 이의 용도
KR101964168B1 (ko) * 2010-10-01 2019-04-01 고쿠리쓰다이가쿠호진 규슈다이가쿠 스트라메노파일의 형질 전환 방법
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MX342216B (es) 2011-07-21 2016-09-20 Dsm Ip Assets Bv Composiciones de acidos grasos.
TW201307553A (zh) * 2011-07-26 2013-02-16 陶氏農業科學公司 在植物中生產二十二碳六烯酸（ｄｈａ）及其他長鏈多元不飽和脂肪酸（ｌｃ－ｐｕｆａ）之技術
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