AU2008254837B2 - Chimeric PUFA polyketide synthase systems and uses thereof - Google Patents

Chimeric PUFA polyketide synthase systems and uses thereof Download PDF

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Publication number
AU2008254837B2
AU2008254837B2 AU2008254837A AU2008254837A AU2008254837B2 AU 2008254837 B2 AU2008254837 B2 AU 2008254837B2 AU 2008254837 A AU2008254837 A AU 2008254837A AU 2008254837 A AU2008254837 A AU 2008254837A AU 2008254837 B2 AU2008254837 B2 AU 2008254837B2
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seq
pufa pks
pks system
nucleic acid
domain
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AU2008254837A1 (en
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Daniel H. Doherty
James G. Metz
Craig A. Weaver
Ross Zirkle
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DSM IP Assets BV
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DSM IP Assets BV
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434—Docosahexenoic acids [DHA]
    • A—HUMAN NECESSITIES
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Oil, Petroleum & Natural Gas (AREA)
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  • Cell Biology (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
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AU2008254837A 2007-05-16 2008-05-16 Chimeric PUFA polyketide synthase systems and uses thereof Ceased AU2008254837B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/749,686 US8003772B2 (en) 1999-01-14 2007-05-16 Chimeric PUFA polyketide synthase systems and uses thereof
US11/749,686 2007-05-16
PCT/US2008/063835 WO2008144473A2 (en) 2007-05-16 2008-05-16 Chimeric pufa polyketide synthase systems and uses thereof

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AU2008254837A1 AU2008254837A1 (en) 2008-11-27
AU2008254837B2 true AU2008254837B2 (en) 2013-09-12

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AU2008254837A Ceased AU2008254837B2 (en) 2007-05-16 2008-05-16 Chimeric PUFA polyketide synthase systems and uses thereof

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US (3) US8003772B2 (enExample)
EP (1) EP2160470B1 (enExample)
JP (1) JP5551584B2 (enExample)
KR (1) KR101539470B1 (enExample)
CN (1) CN101849014B (enExample)
AU (1) AU2008254837B2 (enExample)
BR (1) BRPI0810302A2 (enExample)
CA (1) CA2687523C (enExample)
ES (1) ES2467918T3 (enExample)
IL (1) IL202131A (enExample)
MX (1) MX2009012395A (enExample)
WO (1) WO2008144473A2 (enExample)

Cited By (1)

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US7247461B2 (en) * 1999-01-14 2007-07-24 Martek Biosciences Corporation Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof
US20070244192A1 (en) * 1999-01-14 2007-10-18 Martek Biosciences Corporation Plant seed oils containing polyunsaturated fatty acids
US7211418B2 (en) * 1999-01-14 2007-05-01 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
US7217856B2 (en) * 1999-01-14 2007-05-15 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
TWI324181B (en) 2001-04-16 2010-05-01 Martek Biosciences Corp Product and process for transformation of thraustochytriales microorganisms
PL1756280T3 (pl) 2004-04-22 2015-04-30 Commw Scient Ind Res Org Synteza długołańcuchowych wielonienasyconych kwasów tłuszczowych w komórkach rekombinowanych
ES2529572T3 (es) 2004-04-22 2015-02-23 Commonwealth Scientific And Industrial Research Organisation Síntesis de ácidos grasos poliinsaturados de cadena larga por células recombinantes
MX340759B (es) * 2006-03-15 2015-03-11 Dsm Ip Assets B V * Aceites de semillas vegetales que contienen ácidos grasos poli-insaturados.
BRPI0716075A2 (pt) 2006-08-29 2013-08-06 Commw Scient Ind Res Org sÍntese de Ácidos graxos
CN102076355B (zh) 2008-04-29 2014-05-07 Abbvie公司 双重可变结构域免疫球蛋白及其用途
SG191639A1 (en) 2008-06-03 2013-07-31 Abbott Lab Dual variable domain immunoglobulins and uses thereof
CA3015426C (en) 2008-11-18 2020-01-14 Commonwealth Scientific And Industrial Research Organisation Recombinant cells comprising exogenous .delta.5 and .delta.6 desaturases, .delta.5 and .delta.6 elongases, and .delta.4 desaturases
US8207363B2 (en) 2009-03-19 2012-06-26 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
ES2717102T3 (es) 2009-03-19 2019-06-19 Dsm Ip Assets Bv Moléculas de ácido nucleico de ácido graso poliinsaturado sintasas, y polipéptidos, composiciones y métodos de preparación y usos de los mismos
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CN107746869A (zh) * 2009-12-28 2018-03-02 赛诺菲疫苗技术公司 微藻中异源多肽的生产，微藻胞外体、组合物及其制备方法和用途
US20110195448A1 (en) * 2009-12-28 2011-08-11 James Casey Lippmeier Recombinant Thraustochytrids that Grow on Xylose, and Compositions, Methods of Making, and Uses Thereof
CN103068965A (zh) 2009-12-28 2013-04-24 Dsmip资产公司 在蔗糖上生长的重组破囊壶菌和其组合物、制备方法及用途
WO2011090708A2 (en) 2009-12-28 2011-07-28 Merial Limited Recombinant ndv antigen and uses thereof
CA2993690C (en) * 2010-01-19 2022-03-22 Dsm Ip Assets B.V. Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
US9345759B2 (en) 2010-03-12 2016-05-24 Merial, Inc. Bluetongue virus recombinant vaccines and uses thereof
US11236351B2 (en) * 2010-05-17 2022-02-01 Dow Agrosciences Llc Production of DHA and other LC PUFAs in plants
TW201144442A (en) * 2010-05-17 2011-12-16 Dow Agrosciences Llc Production of DHA and other LC-PUFAs in plants
UY33492A (es) 2010-07-09 2012-01-31 Abbott Lab Inmunoglobulinas con dominio variable dual y usos de las mismas
TW201206473A (en) 2010-08-03 2012-02-16 Abbott Lab Dual variable domain immunoglobulins and uses thereof
CN106434392A (zh) * 2010-10-01 2017-02-22 国立大学法人九州大学 原生藻菌的转化方法
PT2683824T (pt) * 2011-03-07 2018-06-07 Dsm Nutritional Products Ag Modificação de microorganismos thraustochytrid
EA035287B1 (ru) 2011-07-21 2020-05-25 ДСМ АйПи АССЕТС Б.В. Микроорганизмы, продуцирующие эйкозапентаеновую кислоту, композиции, содержащие жирные кислоты, и способы их получения и применения
TW201307553A (zh) * 2011-07-26 2013-02-16 Dow Agrosciences Llc 在植物中生產二十二碳六烯酸（ｄｈａ）及其他長鏈多元不飽和脂肪酸（ｌｃ－ｐｕｆａ）之技術
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