JP5536504B2 - 血糖降下作用増強剤 - Google Patents

血糖降下作用増強剤 Download PDF

Info

Publication number
JP5536504B2
JP5536504B2 JP2010069561A JP2010069561A JP5536504B2 JP 5536504 B2 JP5536504 B2 JP 5536504B2 JP 2010069561 A JP2010069561 A JP 2010069561A JP 2010069561 A JP2010069561 A JP 2010069561A JP 5536504 B2 JP5536504 B2 JP 5536504B2
Authority
JP
Japan
Prior art keywords
group
bacteria
bacterium
lactic acid
acid bacteria
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2010069561A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010248185A (ja
Inventor
康浩 伊佐
真木 嶋川
裕史 大野
秀樹 山村
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biofermin Pharmaceutical Co Ltd
Original Assignee
Biofermin Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biofermin Pharmaceutical Co Ltd filed Critical Biofermin Pharmaceutical Co Ltd
Priority to JP2010069561A priority Critical patent/JP5536504B2/ja
Publication of JP2010248185A publication Critical patent/JP2010248185A/ja
Application granted granted Critical
Publication of JP5536504B2 publication Critical patent/JP5536504B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/133—Amines having hydroxy groups, e.g. sphingosine
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/02—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof containing fruit or vegetable juices
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/065—Microorganisms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/44—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton bound to carbon atoms of the same ring or condensed ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/21—Streptococcus, lactococcus
    • A23V2400/225—Faecalis
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/51—Bifidobacterium
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/51—Bifidobacterium
    • A23V2400/517—Bifidum

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2010069561A 2009-03-26 2010-03-25 血糖降下作用増強剤 Active JP5536504B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2010069561A JP5536504B2 (ja) 2009-03-26 2010-03-25 血糖降下作用増強剤

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2009077555 2009-03-26
JP2009077555 2009-03-26
JP2010069561A JP5536504B2 (ja) 2009-03-26 2010-03-25 血糖降下作用増強剤

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014089153A Division JP5932878B2 (ja) 2009-03-26 2014-04-23 血糖降下作用増強剤

Publications (2)

Publication Number Publication Date
JP2010248185A JP2010248185A (ja) 2010-11-04
JP5536504B2 true JP5536504B2 (ja) 2014-07-02

Family

ID=42781065

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2010069561A Active JP5536504B2 (ja) 2009-03-26 2010-03-25 血糖降下作用増強剤
JP2014089153A Active JP5932878B2 (ja) 2009-03-26 2014-04-23 血糖降下作用増強剤

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2014089153A Active JP5932878B2 (ja) 2009-03-26 2014-04-23 血糖降下作用増強剤

Country Status (5)

Country Link
US (1) US8889375B2 (https=)
JP (2) JP5536504B2 (https=)
MY (1) MY176503A (https=)
SG (2) SG174540A1 (https=)
WO (1) WO2010110374A1 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012011174A1 (ja) * 2010-07-22 2012-01-26 ビオフェルミン製薬株式会社 脂質代謝改善剤、脂質代謝改善作用増強剤、抗肥満剤及び抗肥満作用増強剤
JP5681533B2 (ja) * 2011-03-14 2015-03-11 ビオフェルミン製薬株式会社 消化管痛の予防又は軽減剤
EP3320908B1 (en) * 2015-07-07 2023-09-06 Toa Pharmaceutical Co., Ltd. Bacteria-containing oral rapidly disintegrating tablet
KR101697260B1 (ko) * 2015-07-27 2017-01-17 고려대학교 산학협력단 보글리보즈를 유효성분으로 함유하는 비만 개선, 정장 또는 장내 균총 개선용 조성물
JP6637725B2 (ja) * 2015-10-28 2020-01-29 ビオフェルミン製薬株式会社 ウイルス感染症の予防及び／又は治療剤
WO2018043706A1 (ja) 2016-09-02 2018-03-08 富士フイルム株式会社 家畜用飼料又は家畜用サプリメント、ラクトバチルス属細菌の増殖促進剤、並びにラクトバチルス属細菌の増殖促進方法
JP7235270B2 (ja) * 2018-02-09 2023-03-08 エースバイオプロダクト株式会社 血糖値上昇抑制剤及び同血糖値上昇抑制剤の製造方法
US10966440B2 (en) * 2019-01-05 2021-04-06 Foremost Technologies and Products, Inc. High pressure processing of foods and food supplements
CN111748000B (zh) * 2019-03-29 2022-05-20 沈阳药科大学 3-脱氧-5-羟基-1-氨基碳糖类化合物及其用途
JP2020184909A (ja) * 2019-05-13 2020-11-19 学校法人帝京大学 血糖降下剤、及び、該血糖降下剤を含有する飲食品
CN112386612A (zh) * 2020-12-01 2021-02-23 贾卫国 一种用于预防糖尿病的益生菌生物制剂及其制备工艺
EP4301765A4 (en) * 2021-03-03 2025-03-12 Emergent Product Development Gaithersburg Inc. VALIOLAMINE DERIVATIVES AS GLUCOSIDASINE INHIBITORS
CN118620807B (zh) * 2024-08-15 2024-10-22 山东健源生物科技有限公司 一株具有减肥、降血糖作用的乳酸片球菌及其后生元和应用
CN120758417A (zh) * 2025-07-15 2025-10-10 广州工商学院 一株乳酸乳球菌及其应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU596961B2 (en) * 1985-03-08 1990-05-24 Takeda Chemical Industries Ltd. Saccharide digestion inhibiting composition
ZA927277B (en) 1991-10-02 1993-05-19 Boston Ocular Res Dry eye treatment process and solution.
JPH08298982A (ja) * 1995-05-02 1996-11-19 Aasu Giken:Kk 複合微生物製剤
JPH107577A (ja) 1996-06-17 1998-01-13 Yakult Honsha Co Ltd 血糖降下剤
JP2004113068A (ja) * 2002-09-25 2004-04-15 Sanwa Kosan Kk 腸内ビフィズス菌増殖促進剤
US7108869B2 (en) * 2002-11-07 2006-09-19 Access Business Group International Llc Nutritional supplement containing alpha-glucosidase and alpha-amylase inhibitors
JP2004357505A (ja) * 2003-05-30 2004-12-24 Fancl Corp 胃腸疾患予防・軽減のための犬用サプリメント
JP4463525B2 (ja) * 2003-10-23 2010-05-19 ビオフェルミン製薬株式会社 減感作療法用剤
JP2006020581A (ja) * 2004-07-08 2006-01-26 Cdom:Kk ペット用食品及びその製造方法
JP2006020606A (ja) 2004-07-09 2006-01-26 Someya Hideo 肥満防止、改善のための健康食品用組成物
JP2006055116A (ja) * 2004-08-23 2006-03-02 Michiyo Miura α−グルコシダーゼ活性阻害食品
MX2008015031A (es) * 2006-05-26 2008-12-05 Nestec Sa Metodos de uso y composiciones nutritivas de extracto de touchi.
JP2007330124A (ja) 2006-06-13 2007-12-27 Kenko Tsusho Kk 肥満及び生活習慣病の防止・改善をする為の健康食品用組成物
WO2008093670A1 (ja) 2007-02-01 2008-08-07 Tk Bio-Research Laboratory Co., Ltd. ブドウ果皮・種子乳酸菌発酵物、並びにそれを利用した医薬及び食品
JP2008222701A (ja) * 2007-03-09 2008-09-25 Kangwon National Univ Industry Cooperation Foundation 肥満予防及び治療用発酵物、糖尿病予防用発酵物、肥満予防及び治療用発酵食品および糖尿病予防用食品

Also Published As

Publication number Publication date
US8889375B2 (en) 2014-11-18
WO2010110374A1 (ja) 2010-09-30
JP2014141526A (ja) 2014-08-07
MY176503A (en) 2020-08-12
US20120014923A1 (en) 2012-01-19
JP2010248185A (ja) 2010-11-04
JP5932878B2 (ja) 2016-06-08
SG10201400931RA (en) 2014-07-30
SG174540A1 (en) 2011-10-28

Similar Documents

Publication Publication Date Title
JP5932878B2 (ja) 血糖降下作用増強剤
KR101992537B1 (ko) 신규한 락토바실러스 사케이 및 이를 포함하는 조성물
CN104740138A (zh) 包含芦荟、益生菌和益生元的组合物及其用途
KR102136522B1 (ko) 안전성 및 장부착능이 우수한 모유유래 락토바실러스 루테리 lm1071 균주, 및 상기 균주 또는 이의 배양물을 포함하는 조성물
CN103082292A (zh) 罗斯氏菌（Roseburia）在治疗和预防肥胖相关疾病中的应用
EP3202892A1 (en) Uses of bacteroides in treatment or prevention of obesity-related diseases
CN111528479A (zh) 一种缓解特应性皮炎功能的益生菌和益生元组合物及应用
EP3202891B1 (en) Uses of bacteroides in treatment or prevention of obesity or diabetes
JP2017081853A (ja) ウイルス感染症の予防及び／又は治療剤
CN118256375A (zh) 一株用于调节血压及糖脂代谢的罗伊氏粘液乳杆菌及其应用
WO2019041141A1 (zh) 解纤维素拟杆菌在制备预防和/或治疗脂质代谢相关疾病制剂中的应用
JP5769710B2 (ja) 脂質代謝改善剤、脂質代謝改善作用増強剤、抗肥満剤及び抗肥満作用増強剤
JP5681533B2 (ja) 消化管痛の予防又は軽減剤
JPH072647B2 (ja) 糖消化抑制剤および糖消化抑制組成物
US20240277785A1 (en) Composition for preventing or treating inflammatory bowel disease
JP5631721B2 (ja) 胃腸機能亢進剤
CN110869035B (zh) 沙氏别样杆菌在制备预防和/或治疗脂质代谢性相关疾病组合物中的应用
JP6402016B2 (ja) 神経機能改善剤
WO2021111981A1 (ja) 認知症の予防又は改善用剤及びそれを含む組成物
KR102791846B1 (ko) 인체에서 체지방량을 감소시키기 위한 조성물 및 이의 용도
CN117771280A (zh) 一种用于缓解高尿酸血症的组合物及其应用
JP2023128589A (ja) 腸管免疫賦活剤及びＩｇＡ産生促進剤
CN119331778A (zh) 一种用于辅助治疗糖尿病的乳酸菌组合物及复合乳酸菌益生菌剂和应用
WO2021111980A1 (ja) 起立性低血圧の予防又は改善用剤及びそれを含む組成物
JP2020180075A (ja) 糖尿病予防治療剤、血糖値上昇抑制剤、血糖値スパイク抑制剤及びグルコース取り込み阻害剤

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20120926

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20131217

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140214

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20140311

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140318

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20140408

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20140424

R150 Certificate of patent or registration of utility model

Ref document number: 5536504

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

S531 Written request for registration of change of domicile

Free format text: JAPANESE INTERMEDIATE CODE: R313531

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

S531 Written request for registration of change of domicile

Free format text: JAPANESE INTERMEDIATE CODE: R313531

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250