JP5535076B2 - 肝臓癌を治療するための標的化ミクロｒｎａ - Google Patents

肝臓癌を治療するための標的化ミクロｒｎａ Download PDF

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JP5535076B2
JP5535076B2 JP2010532219A JP2010532219A JP5535076B2 JP 5535076 B2 JP5535076 B2 JP 5535076B2 JP 2010532219 A JP2010532219 A JP 2010532219A JP 2010532219 A JP2010532219 A JP 2010532219A JP 5535076 B2 JP5535076 B2 JP 5535076B2
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certain embodiments
modified oligonucleotide
nucleobase sequence
modified
mir
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JP2011501962A5 (https=
JP2011501962A (ja
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シー・フランク・ベネット
アイェレト・チャジュト
クリスティン・エサウ
エリック・ジー・マーカッソン
ノガ・イェルシャルミ
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Regulus Therapeutics Inc
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JP2010532219A 2007-10-29 2008-10-29 肝臓癌を治療するための標的化ミクロｒｎａ Active JP5535076B2 (ja)

Applications Claiming Priority (3)

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US98323107P 2007-10-29 2007-10-29
US60/983,231 2007-10-29
PCT/US2008/081645 WO2009058907A2 (en) 2007-10-29 2008-10-29 Targeting micrornas for the treatment of liver cancer

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JP2011501962A JP2011501962A (ja) 2011-01-20
JP2011501962A5 JP2011501962A5 (https=) 2012-05-10
JP5535076B2 true JP5535076B2 (ja) 2014-07-02

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US (6) US8211867B2 (https=)
EP (1) EP2217248B1 (https=)
JP (1) JP5535076B2 (https=)
CN (1) CN101980712B (https=)
AU (1) AU2008318778B2 (https=)
CA (1) CA2704043C (https=)
IL (1) IL205307A (https=)
WO (1) WO2009058907A2 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11236337B2 (en) 2016-11-01 2022-02-01 The Research Foundation For The State University Of New York 5-halouracil-modified microRNAs and their use in the treatment of cancer
US11584932B2 (en) 2016-11-01 2023-02-21 The Research Foundation For The State University Of New York 5-halouracil-modified microRNAs and their use in the treatment of cancer
US12319913B2 (en) 2018-10-31 2025-06-03 The Research Foundation For The State University Of New York 5-halouracil-modified microRNAs and their use in the treatment of cancer

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CA2817982C (en) 2010-11-15 2020-06-30 The Regents Of The University Of Michigan Controlled release mucoadhesive systems
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JP2014506791A (ja) 2011-02-03 2014-03-20 マーナ セラピューティクス インコーポレイテッド ｍｉＲ−３４の合成模倣体
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