JP5530065B2 - 抗生物質耐性欠失ワクチンの作成方法 - Google Patents

抗生物質耐性欠失ワクチンの作成方法 Download PDF

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JP5530065B2
JP5530065B2 JP2007525861A JP2007525861A JP5530065B2 JP 5530065 B2 JP5530065 B2 JP 5530065B2 JP 2007525861 A JP2007525861 A JP 2007525861A JP 2007525861 A JP2007525861 A JP 2007525861A JP 5530065 B2 JP5530065 B2 JP 5530065B2
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listeria
strain
gene
vaccine strain
enzyme
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JP2008509677A (ja
JP2008509677A5 (https=
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パターソン、イボンヌ
ベルチ、ソーステン
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ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y206/00—Transferases transferring nitrogenous groups (2.6)
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    • C12Y206/00—Transferases transferring nitrogenous groups (2.6)
    • C12Y206/01—Transaminases (2.6.1)
    • C12Y206/01021—D-Amino-acid transaminase (2.6.1.21), i.e. D-alanine aminotransferase/transaminase or D-aspartic aminotransferase/transaminase
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    • C12Y501/00—Racemaces and epimerases (5.1)
    • C12Y501/01—Racemaces and epimerases (5.1) acting on amino acids and derivatives (5.1.1)
    • C12Y501/01001—Alanine racemase (5.1.1.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
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    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/00034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20033—Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory

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  • Bioinformatics & Cheminformatics (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Oncology (AREA)
JP2007525861A 2004-08-13 2005-08-15 抗生物質耐性欠失ワクチンの作成方法 Expired - Fee Related JP5530065B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US60149204P 2004-08-13 2004-08-13
US60/601,492 2004-08-13
PCT/US2005/028895 WO2006017856A2 (en) 2004-08-13 2005-08-15 Methods for constructing antibiotic resistance free vaccines

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JP2008509677A JP2008509677A (ja) 2008-04-03
JP2008509677A5 JP2008509677A5 (https=) 2008-06-26
JP5530065B2 true JP5530065B2 (ja) 2014-06-25

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US (4) US8906664B2 (https=)
EP (2) EP2942391B1 (https=)
JP (1) JP5530065B2 (https=)
AU (1) AU2005271246A1 (https=)
CA (1) CA2577306A1 (https=)
DK (2) DK2942391T3 (https=)
ES (2) ES2543079T3 (https=)
PT (2) PT2942391T (https=)
WO (1) WO2006017856A2 (https=)

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KR102052108B1 (ko) * 2019-08-16 2019-12-04 주식회사 쎌바이오텍 영양요구성 마커를 포함하는 재조합 플라스미드, 이를 포함하는 항암 약물 위장관 전달용 미생물 및 그를 포함하는 항암 약제학적 조성물

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PT2942391T (pt) 2004-08-13 2018-10-09 Univ Pennsylvania Métodos de produção de vacinas não resistentes aos antibióticos
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PT2942391T (pt) 2018-10-09
WO2006017856A9 (en) 2006-10-19
EP1789559B1 (en) 2015-05-20
EP1789559A2 (en) 2007-05-30
EP1789559A4 (en) 2009-02-11
US9700608B2 (en) 2017-07-11
JP2008509677A (ja) 2008-04-03
WO2006017856A2 (en) 2006-02-16
US20060104991A1 (en) 2006-05-18
US20150125480A1 (en) 2015-05-07
US9492527B2 (en) 2016-11-15
US10426823B2 (en) 2019-10-01
AU2005271246A1 (en) 2006-02-16
US20170281691A1 (en) 2017-10-05
ES2543079T3 (es) 2015-08-14
US8906664B2 (en) 2014-12-09
EP2942391A1 (en) 2015-11-11
ES2684749T3 (es) 2018-10-04
HK1217108A1 (en) 2016-12-23
WO2006017856A3 (en) 2006-08-31
PT1789559E (pt) 2015-10-09
DK2942391T3 (en) 2018-08-27
DK1789559T3 (en) 2015-08-24
CA2577306A1 (en) 2006-02-16
US20170028045A1 (en) 2017-02-02
EP2942391B1 (en) 2018-05-23

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