JP5524215B2 - 抗菌剤として有用なヒドロキサム酸誘導体 - Google Patents

抗菌剤として有用なヒドロキサム酸誘導体 Download PDF

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JP5524215B2
JP5524215B2 JP2011527431A JP2011527431A JP5524215B2 JP 5524215 B2 JP5524215 B2 JP 5524215B2 JP 2011527431 A JP2011527431 A JP 2011527431A JP 2011527431 A JP2011527431 A JP 2011527431A JP 5524215 B2 JP5524215 B2 JP 5524215B2
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alkyl
compound
biphenyl
ylmethoxy
methyl
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JP2012502974A (ja
JP2012502974A5 (OSRAM
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フランク ブラウン マシュー
フランシス ドノヴァン チャールズ
リー エルスウォース エドマンド
ウェイド ホイヤー デントン
アレン ジョンソン ティモシー
シン ラル マンジンダー
リンバーラキス クリス
ティモシー マーフィー シーン
アン シェリー デブラ
ベントレイ テイラー クラーク
スコット ウァーマス ジョセフ
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ファイザー・インク
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    • C07—ORGANIC CHEMISTRY
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    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
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    • C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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