MX2021011026A - Forma cristalina de un derivado de avibactam. - Google Patents

Forma cristalina de un derivado de avibactam.

Info

Publication number
MX2021011026A
MX2021011026A MX2021011026A MX2021011026A MX2021011026A MX 2021011026 A MX2021011026 A MX 2021011026A MX 2021011026 A MX2021011026 A MX 2021011026A MX 2021011026 A MX2021011026 A MX 2021011026A MX 2021011026 A MX2021011026 A MX 2021011026A
Authority
MX
Mexico
Prior art keywords
crystalline form
avibactam derivative
crystalline
derivative
avibactam
Prior art date
Application number
MX2021011026A
Other languages
English (en)
Inventor
Sami Karaborni
Original Assignee
Arixa Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arixa Pharmaceuticals Inc filed Critical Arixa Pharmaceuticals Inc
Publication of MX2021011026A publication Critical patent/MX2021011026A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se proveen una forma cristalina de un derivado de avibactam (1), es decir, anhidrato de 3-(((((1R,2S,5R)-2-carbamoil-7-oxo-1,6-diaz abiciclo[3.2.1]octan-6-il)oxi)sulfonil)oxi)-2,2-dimetilpropanoato de etilo cristalino, composiciones farmacéuticas del mismo, y el uso del derivado de avibactam cristalino para tratar infecciones bacterianas.
MX2021011026A 2019-03-12 2020-03-10 Forma cristalina de un derivado de avibactam. MX2021011026A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962817243P 2019-03-12 2019-03-12
PCT/US2020/021795 WO2020185729A1 (en) 2019-03-12 2020-03-10 Crystalline form of an avibactam derivative

Publications (1)

Publication Number Publication Date
MX2021011026A true MX2021011026A (es) 2021-10-13

Family

ID=70155371

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021011026A MX2021011026A (es) 2019-03-12 2020-03-10 Forma cristalina de un derivado de avibactam.

Country Status (11)

Country Link
US (1) US11008321B2 (es)
EP (1) EP3938366A1 (es)
JP (1) JP2022524118A (es)
KR (1) KR20210137159A (es)
CN (1) CN113614084A (es)
AU (1) AU2020237440B2 (es)
BR (1) BR112021017874A2 (es)
CA (1) CA3133071A1 (es)
MX (1) MX2021011026A (es)
SG (1) SG11202108905UA (es)
WO (1) WO2020185729A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210186983A1 (en) * 2019-12-20 2021-06-24 Arixa Pharmaceuticals, Inc. Orally administered combinations of amoxicillin and avibactam derivatives for treating mycobacterial infections

Family Cites Families (30)

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US20090099253A1 (en) 2007-10-15 2009-04-16 Xenoport, Inc. Internally Masked Neopentyl Sulfonyl Ester Cyclization Release Prodrugs of Acamprosate, Compositions Thereof, and Methods of Use
PT2231667E (pt) 2008-01-18 2013-12-13 Merck Sharp & Dohme Inibidores de beta-lactamase
GB0801401D0 (en) 2008-01-25 2008-03-05 Barry Callebaut Ag Composition
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WO2010126820A2 (en) 2009-04-30 2010-11-04 Merck Sharp & Dohme Corp. Preparation of alkyl esters of n-protected oxo-azacycloalkylcarboxylic acids
MX2012004377A (es) 2009-10-14 2012-06-01 Merck Sharp & Dohme Piperidinas sustituidas que aumentan la actividad de p53 y sus usos.
PT2562155T (pt) 2010-04-20 2019-09-10 Taisho Pharmaceutical Co Ltd Derivado de ácido hidroxâmico
US20110294879A1 (en) 2010-05-28 2011-12-01 Xenoport, Inc. Method of treatment of fragile x syndrome, down's syndrome, autism and related disorders
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ES2565092T3 (es) 2011-05-30 2016-03-31 Sumitomo Chemical Co., Ltd. Compuestos de ciclohexanona y herbicidas que los comprenden
US8796257B2 (en) 2011-12-02 2014-08-05 Naeja Pharmaceutical Inc. Bicyclic compounds and their use as antibacterial agents and β-lactamase inhibitors
RU2017112319A (ru) 2014-09-12 2018-10-12 Тояма Кемикал Ко., Лтд. Новая фармацевтическая композиция, содержащая производное гидроксамовой кислоты или его соль
BR112017004796A2 (pt) 2014-09-12 2017-12-12 Toyama Chemical Co Ltd método para utilizar derivados de ácido hidroxâmico e substância antibacterial em combinação
WO2016116788A1 (en) 2015-01-24 2016-07-28 Wockhardt Limited Nitrogen containing bicyclic compounds and their use in treatment of bacterial infections
MX2017013792A (es) 2015-09-16 2018-07-06 Xuanzhu Pharma Co Ltd INHIBIDORES DE íŸ-LACTAMASA Y USOS DE LOS MISMOS.
US20170165371A1 (en) 2017-02-22 2017-06-15 Joel Steven Goldberg Novel synthesis of potential ester prodrugs
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Also Published As

Publication number Publication date
KR20210137159A (ko) 2021-11-17
SG11202108905UA (en) 2021-09-29
CN113614084A (zh) 2021-11-05
BR112021017874A2 (pt) 2021-12-07
US20200291022A1 (en) 2020-09-17
EP3938366A1 (en) 2022-01-19
US11008321B2 (en) 2021-05-18
WO2020185729A1 (en) 2020-09-17
AU2020237440A1 (en) 2021-09-09
CA3133071A1 (en) 2020-09-17
AU2020237440B2 (en) 2022-10-20
JP2022524118A (ja) 2022-04-27

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