JP5453261B2 - 生物活性ペプチドの発現および精製のための可溶性タグ - Google Patents

生物活性ペプチドの発現および精製のための可溶性タグ Download PDF

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Publication number
JP5453261B2
JP5453261B2 JP2010518341A JP2010518341A JP5453261B2 JP 5453261 B2 JP5453261 B2 JP 5453261B2 JP 2010518341 A JP2010518341 A JP 2010518341A JP 2010518341 A JP2010518341 A JP 2010518341A JP 5453261 B2 JP5453261 B2 JP 5453261B2
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peptide
interest
seq
inclusion body
fusion
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Expired - Fee Related
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Japanese (ja)
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JP2010534477A (ja
JP2010534477A5 (enExample
Inventor
ケイ・チェン
リンダ・ジェーン・デカロリス
ステファン・アール・ファーネストック
ターニャ・マリア・グリューバー
リーザ・ダイアン・ライス
ピエール・ウ・ルヴィール
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EIDP Inc
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EI Du Pont de Nemours and Co
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90Isomerases (5.)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/50Fusion polypeptide containing protease site

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2010518341A 2007-07-25 2008-07-23 生物活性ペプチドの発現および精製のための可溶性タグ Expired - Fee Related JP5453261B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/782,836 US7678883B2 (en) 2007-07-25 2007-07-25 Solubility tags for the expression and purification of bioactive peptides
US11/782,836 2007-07-25
PCT/US2008/070802 WO2009015165A1 (en) 2007-07-25 2008-07-23 Solubility tags for the expression and purification of bioactive peptides

Publications (3)

Publication Number Publication Date
JP2010534477A JP2010534477A (ja) 2010-11-11
JP2010534477A5 JP2010534477A5 (enExample) 2011-08-18
JP5453261B2 true JP5453261B2 (ja) 2014-03-26

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JP2010518341A Expired - Fee Related JP5453261B2 (ja) 2007-07-25 2008-07-23 生物活性ペプチドの発現および精製のための可溶性タグ

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Country Link
US (2) US7678883B2 (enExample)
EP (1) EP2173877B1 (enExample)
JP (1) JP5453261B2 (enExample)
KR (1) KR20100057016A (enExample)
CN (1) CN101835898B (enExample)
AU (1) AU2008279186B2 (enExample)
CA (1) CA2689099A1 (enExample)
ES (1) ES2439702T3 (enExample)
IL (1) IL203002A0 (enExample)
WO (1) WO2009015165A1 (enExample)

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US9273336B2 (en) 2011-02-21 2016-03-01 E. I. Du Pont De Nemours And Company Recombinant host cells having an increase in buoyant density
US9115182B2 (en) 2011-06-21 2015-08-25 E I Du Pont De Nemours And Company Cysteine cross-linked structural peptides
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CN104755502B (zh) * 2012-10-12 2018-05-18 清华大学 多肽的产生和纯化方法
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CN104513298B (zh) * 2014-12-09 2018-07-17 山东信得科技股份有限公司 一种表达鸡传染性法氏囊可溶性vp 2-4-3多肽的方法
JP6640226B2 (ja) * 2014-12-29 2020-02-05 アグリカルチュラル テクノロジー リサーチ インスティテュート 発現エレメント、発現カセット、及びそれらを含むベクター
GB2540763A (en) 2015-07-24 2017-02-01 Evocatal Gmbh Catalytically active protein aggregates and methods for producing the same
WO2020053239A1 (en) * 2018-09-11 2020-03-19 Nanotag Biotechnologies Gmbh Epitope tags recognized by specific binders
WO2023008415A1 (ja) * 2021-07-27 2023-02-02 STAND Therapeutics株式会社 ペプチドタグおよび当該ペプチドタグをコードする核酸
US20250042946A1 (en) 2021-12-08 2025-02-06 Oakgrove Bio Llc Biological Production of Histidine-Rich Peptides
EP4567108A1 (en) * 2023-12-05 2025-06-11 Kutzner, Christoph Screening of target peptides using fusion polypeptides

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Also Published As

Publication number Publication date
AU2008279186B2 (en) 2013-09-05
EP2173877A1 (en) 2010-04-14
CN101835898B (zh) 2013-01-02
US7794979B2 (en) 2010-09-14
JP2010534477A (ja) 2010-11-11
WO2009015165A1 (en) 2009-01-29
IL203002A0 (en) 2011-08-01
AU2008279186A1 (en) 2009-01-29
EP2173877B1 (en) 2013-10-02
CA2689099A1 (en) 2009-01-29
CN101835898A (zh) 2010-09-15
US20090029412A1 (en) 2009-01-29
ES2439702T3 (es) 2014-01-24
KR20100057016A (ko) 2010-05-28
US20100136621A1 (en) 2010-06-03
US7678883B2 (en) 2010-03-16

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