IL203002A0 - Solubility tags for the expression and purification of bioactive peptides - Google Patents

Solubility tags for the expression and purification of bioactive peptides

Info

Publication number
IL203002A0
IL203002A0 IL203002A IL20300209A IL203002A0 IL 203002 A0 IL203002 A0 IL 203002A0 IL 203002 A IL203002 A IL 203002A IL 20300209 A IL20300209 A IL 20300209A IL 203002 A0 IL203002 A0 IL 203002A0
Authority
IL
Israel
Prior art keywords
purification
expression
bioactive peptides
solubility tags
tags
Prior art date
Application number
IL203002A
Other languages
English (en)
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of IL203002A0 publication Critical patent/IL203002A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL203002A 2007-07-25 2009-12-27 Solubility tags for the expression and purification of bioactive peptides IL203002A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/782,836 US7678883B2 (en) 2007-07-25 2007-07-25 Solubility tags for the expression and purification of bioactive peptides
PCT/US2008/070802 WO2009015165A1 (en) 2007-07-25 2008-07-23 Solubility tags for the expression and purification of bioactive peptides

Publications (1)

Publication Number Publication Date
IL203002A0 true IL203002A0 (en) 2011-08-01

Family

ID=39967949

Family Applications (1)

Application Number Title Priority Date Filing Date
IL203002A IL203002A0 (en) 2007-07-25 2009-12-27 Solubility tags for the expression and purification of bioactive peptides

Country Status (10)

Country Link
US (2) US7678883B2 (enExample)
EP (1) EP2173877B1 (enExample)
JP (1) JP5453261B2 (enExample)
KR (1) KR20100057016A (enExample)
CN (1) CN101835898B (enExample)
AU (1) AU2008279186B2 (enExample)
CA (1) CA2689099A1 (enExample)
ES (1) ES2439702T3 (enExample)
IL (1) IL203002A0 (enExample)
WO (1) WO2009015165A1 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9101687B2 (en) 2002-07-15 2015-08-11 University Of Leeds Beta sheet tapes ribbons in tissue engineering
US8586539B2 (en) 2002-07-15 2013-11-19 University Of Leeds Beta sheet tapes ribbons in tissue engineering
US7951559B2 (en) * 2007-07-25 2011-05-31 E.I. Du Pont De Nemours And Company Recombinant peptide production using a cross-linkable solubility tag
US7829311B2 (en) * 2007-07-25 2010-11-09 E.I. Du Pont De Nemours And Company Ketosteroid isomerase inclusion body tag engineered to be acid-resistant by replacing aspartates with glutamate
US7915011B2 (en) * 2009-03-05 2011-03-29 E.I. Du Pont De Nemours And Company Host cell modifications that improve peptide production and downstream processing
US9241987B2 (en) 2009-11-20 2016-01-26 The University Of Chicago Methods and compositions related to immunogenic fibrils
US8609621B2 (en) 2010-11-15 2013-12-17 E I Du Pont De Nemours And Company Acid-cleavable linkers exhibiting altered rates of acid hydrolysis
US9273336B2 (en) 2011-02-21 2016-03-01 E. I. Du Pont De Nemours And Company Recombinant host cells having an increase in buoyant density
US9115182B2 (en) 2011-06-21 2015-08-25 E I Du Pont De Nemours And Company Cysteine cross-linked structural peptides
US9062312B2 (en) 2011-06-21 2015-06-23 Danisco Us Inc. Fusion peptides comprising multi-functional peptidic solubility tags for efficient production, processing and surface applications
CN104755502B (zh) * 2012-10-12 2018-05-18 清华大学 多肽的产生和纯化方法
GB201306338D0 (en) 2013-04-08 2013-05-22 Univ Leeds Novel proteoglycans
CN104513298B (zh) * 2014-12-09 2018-07-17 山东信得科技股份有限公司 一种表达鸡传染性法氏囊可溶性vp 2-4-3多肽的方法
JP6640226B2 (ja) * 2014-12-29 2020-02-05 アグリカルチュラル テクノロジー リサーチ インスティテュート 発現エレメント、発現カセット、及びそれらを含むベクター
GB2540763A (en) 2015-07-24 2017-02-01 Evocatal Gmbh Catalytically active protein aggregates and methods for producing the same
WO2020053239A1 (en) * 2018-09-11 2020-03-19 Nanotag Biotechnologies Gmbh Epitope tags recognized by specific binders
WO2023008415A1 (ja) * 2021-07-27 2023-02-02 ＳＴＡＮＤ Ｔｈｅｒａｐｅｕｔｉｃｓ株式会社 ペプチドタグおよび当該ペプチドタグをコードする核酸
US20250042946A1 (en) 2021-12-08 2025-02-06 Oakgrove Bio Llc Biological Production of Histidine-Rich Peptides
EP4567108A1 (en) * 2023-12-05 2025-06-11 Kutzner, Christoph Screening of target peptides using fusion polypeptides

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US516362A (en) * 1894-03-13 Retarding device for bolt-actuating mechanism
US641273A (en) * 1899-06-03 1900-01-16 John Dennis Coon Cooking utensil.
US641936A (en) * 1899-08-09 1900-01-23 Edwin R Childs Latticed or leaded glass.
US935642A (en) * 1908-01-09 1909-10-05 Gerhard Coenen Flushing apparatus.
US5206154A (en) 1985-01-28 1993-04-27 Xoma Corporation Method of producing cecropins by microbiological techniques
EP0305481B1 (en) * 1987-03-20 1993-09-29 Creative Biomolecules, Inc. Leader sequences for the production of recombinant proteins
US5215896A (en) 1987-03-20 1993-06-01 Creative Biomolecules, Inc. Leader sequences for the production of recombinant proteins
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
ES2118066T3 (es) 1989-10-05 1998-09-16 Optein Inc Sintesis y aislamiento, exentos de celulas, de nuevos genes y polipeptidos.
US5449754A (en) 1991-08-07 1995-09-12 H & N Instruments, Inc. Generation of combinatorial libraries
US5639603A (en) 1991-09-18 1997-06-17 Affymax Technologies N.V. Synthesizing and screening molecular diversity
JPH08501213A (ja) 1992-08-21 1996-02-13 ザ ユニバーシティー オブ ブリティッシュ コロンビア カチオン性ペプチド及びその製造方法
US5585275A (en) 1992-09-02 1996-12-17 Arris Pharmaceutical Corporation Pilot apparatus for peptide synthesis and screening
US5480971A (en) 1993-06-17 1996-01-02 Houghten Pharmaceuticals, Inc. Peralkylated oligopeptide mixtures
US5648244A (en) 1993-09-27 1997-07-15 President And Fellows Of Harvard College Production, purification, cleavage and use of fusion peptides
US6037145A (en) 1994-09-07 2000-03-14 Suntory Limited Process for production of protein
DK0971946T3 (da) 1997-01-21 2006-10-30 Gen Hospital Corp Selektion af proteiner ved anvendelse af RNA-protein-fusioner
US6261804B1 (en) 1997-01-21 2001-07-17 The General Hospital Corporation Selection of proteins using RNA-protein fusions
US6281018B1 (en) * 1998-02-26 2001-08-28 Coulter International Corp. Selective purification and enrichment sorting of flow cytometer droplets based upon analysis of droplet precursor regions
US6846655B1 (en) 1998-06-29 2005-01-25 Phylos, Inc. Methods for generating highly diverse libraries
AU5220099A (en) 1998-07-31 2000-02-21 Pierce Chemical Company Fusion products containing insoluble proteinaceous tag
ES2329205T3 (es) 1998-08-17 2009-11-23 Bristol-Myers Squibb Company Identificacion de interacciones de compuestos-proteinas usando bibliotecas de moleculas de fusion de proteinas-acidos nucleicos.
JP2002522091A (ja) 1998-08-17 2002-07-23 フィロス インク． ３’非翻訳領域を欠損する核酸を生成して細胞ｒｎａ蛋白質融合体形成を最適化する方法
US6696089B2 (en) 1998-09-03 2004-02-24 Board Of Regents Of The University Of Nebraska Nanogel networks including polyion polymer fragments and biological agent compositions thereof
FR2783169B1 (fr) 1998-09-15 2001-11-02 Sederma Sa Utilisation cosmetique ou dermopharmaceutique de peptides pour la cicatrisation et pour l'amelioration de l'aspect cutane lors du vieillissement naturel ou accelere (heliodermie, pollution)
PT1137812E (pt) 1998-12-02 2007-05-31 Adnexus Therapeutics Inc Fusões adn-proteína e suas utilizações
US6242219B1 (en) 1999-03-18 2001-06-05 Xoma (Us) Llc Methods for recombinant peptide production
IL147037A0 (en) 1999-07-27 2002-08-14 Phylos Inc Peptide acceptor ligation methods
JP4803933B2 (ja) 1999-08-27 2011-10-26 ブリストル−マイヤーズ スクウィブ カンパニー インビトロ翻訳タンパク質の符号化方法および選別方法
DK1268766T3 (da) 2000-03-31 2006-04-10 Cambridge Antibody Tech Forbedringer af ribosom-display
ES2338097T3 (es) 2000-04-14 2010-05-04 Genencor International, Inc. Procedimiento de identificacion selectiva.
US7129326B2 (en) 2000-04-14 2006-10-31 Genencor International, Inc. Methods for selective targeting
GB0117011D0 (en) * 2001-07-12 2001-09-05 Univ Leeds Peptide barrels
US20030185870A1 (en) 2001-11-20 2003-10-02 Grinstaff Mark W. Interfacial biomaterials
EP1532261B1 (en) 2002-05-24 2010-02-10 Medtronic, Inc. Methods and dna constructs for high yield production of polypeptides
EP1554302A4 (en) * 2002-05-24 2006-05-03 Restoragen Inc METHOD AND DNA CONSTRUCTS FOR THE PRODUCTION OF POLYPEPTIDES HAVING A HIGH LEVEL
DE10227238A1 (de) 2002-06-19 2004-01-15 Wella Ag Hochaffine kosmetische Mittel
GB0216286D0 (en) * 2002-07-15 2002-08-21 Univ Leeds Network
EP2581383A1 (en) 2002-11-25 2013-04-17 Genencor International, Inc. Skin or hair binding peptides
AU2003299869A1 (en) 2002-12-26 2004-07-29 Gendron, Inc. Bariatric patient management system
US7309482B2 (en) 2003-09-08 2007-12-18 E.I. Du Pont De Nemours And Company Long lasting waterproof sunscreen comprising metal oxide and peptide conditioner
US7220405B2 (en) 2003-09-08 2007-05-22 E. I. Du Pont De Nemours And Company Peptide-based conditioners and colorants for hair, skin, and nails
US7285264B2 (en) 2003-09-08 2007-10-23 E.I. Du Pont De Nemours And Company Peptide-based body surface coloring reagents
US20050226839A1 (en) 2003-09-08 2005-10-13 Xueying Huang Pepetide-based body surface reagents for personal care
US20050054752A1 (en) 2003-09-08 2005-03-10 O'brien John P. Peptide-based diblock and triblock dispersants and diblock polymers
US7736633B2 (en) 2005-09-28 2010-06-15 E.I. Du Pont De Nemours And Company Method for enhancing effects of colorants and conditioners
US7632919B2 (en) 2005-12-15 2009-12-15 E.I. Du Pont De Nemours And Company Polystyrene binding peptides and methods of use
US7700716B2 (en) 2005-12-15 2010-04-20 E. I. Du Pont De Nemours And Company Polytetrafluoroethylene binding peptides and methods of use
US7906617B2 (en) 2005-12-15 2011-03-15 E. I. Du Pont De Nemours And Company Polyethylene binding peptides and methods of use
US7709601B2 (en) 2005-12-15 2010-05-04 E. I. Du Pont De Nemours And Company Nylon binding peptides and methods of use
US7928076B2 (en) 2005-12-15 2011-04-19 E. I. Du Pont De Nemours And Company Polypropylene binding peptides and methods of use
US7749957B2 (en) 2006-04-06 2010-07-06 E.I. Du Pont De Nemours And Company Clay-binding peptides and methods of use
US7732569B2 (en) 2006-10-19 2010-06-08 E.I. Du Pont De Nemours And Company Zein-based peptide tags for the expression and purification of bioactive peptides
US7662913B2 (en) 2006-10-19 2010-02-16 E. I. Du Pont De Nemours And Company Cystatin-based peptide tags for the expression and purification of bioactive peptides

Also Published As

Publication number Publication date
AU2008279186B2 (en) 2013-09-05
EP2173877A1 (en) 2010-04-14
CN101835898B (zh) 2013-01-02
US7794979B2 (en) 2010-09-14
JP2010534477A (ja) 2010-11-11
WO2009015165A1 (en) 2009-01-29
AU2008279186A1 (en) 2009-01-29
JP5453261B2 (ja) 2014-03-26
EP2173877B1 (en) 2013-10-02
CA2689099A1 (en) 2009-01-29
CN101835898A (zh) 2010-09-15
US20090029412A1 (en) 2009-01-29
ES2439702T3 (es) 2014-01-24
KR20100057016A (ko) 2010-05-28
US20100136621A1 (en) 2010-06-03
US7678883B2 (en) 2010-03-16

Similar Documents

Publication Publication Date Title
GB0700523D0 (en) The Stabilisation Of Proteins
EP1989992A4 (en) ENDOSCOPE SYSTEM
BR112012014254A2 (pt) "artigo de múltiplas camadas"
GB0702020D0 (en) Peptides and their use
GB0612028D0 (en) Bioactive glass
IL202473A0 (en) Substituted benzoylamino-indan-2-carboxylic acids and related compounds
EP2020200A4 (en) ENDOSCOPE SYSTEM
IL203221A (en) Bioactive peptides and antibodies
GB0721162D0 (en) Patient wrist tag
IL202120A0 (en) Signaling peptides
GB0702021D0 (en) Peptides and their use
GB0702022D0 (en) Peptides and their use
PL2464656T3 (pl) Nowy peptyd i jego zastosowanie
GB0626021D0 (en) The stabilisation of proteins
IL216199A (en) A peptide containing the sequence ednimvtfrnqasr
EP2123666A4 (en) PEPTIDE
GB2460965B (en) Fibrillar albumin and uses thereof
GB0703945D0 (en) Peptide
GB0823550D0 (en) Peptide tag and uses thereof
GB0817673D0 (en) Bioactive peptide
GB2438232A8 (en) Article safeguard system
IL198067A0 (en) Improved release of statins in the intestine
GB0705848D0 (en) Bottle tag patent
GB0723451D0 (en) Natural bioactive compounds
GB0710813D0 (en) Peptides and uses thereof