JP5433236B2 - 弱塩基性選択性セロトニン５−ｈｔ３遮断剤および有機酸を含む薬物送達系 - Google Patents

弱塩基性選択性セロトニン５−ｈｔ３遮断剤および有機酸を含む薬物送達系 Download PDF

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JP5433236B2
JP5433236B2 JP2008552611A JP2008552611A JP5433236B2 JP 5433236 B2 JP5433236 B2 JP 5433236B2 JP 2008552611 A JP2008552611 A JP 2008552611A JP 2008552611 A JP2008552611 A JP 2008552611A JP 5433236 B2 JP5433236 B2 JP 5433236B2
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beads
organic acid
water
coating
pharmaceutical composition
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JP2009524697A (ja
JP2009524697A5 (OSRAM
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ベンカテシュ，ゴピ，エム．
レイ，チン−ワン
ヴァヤス，ネハル，エイチ．
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アプタリス ファーマテック，インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2008552611A 2006-01-27 2007-01-29 弱塩基性選択性セロトニン５−ｈｔ３遮断剤および有機酸を含む薬物送達系 Expired - Fee Related JP5433236B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US76275006P 2006-01-27 2006-01-27
US60/762,750 2006-01-27
PCT/US2007/061217 WO2007090082A2 (en) 2006-01-27 2007-01-29 Drug delivery systems comprising weakly basic selective serotonin 5-ht3 blocking agent and organic acids

Related Child Applications (1)

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JP2013165542A Division JP5918179B2 (ja) 2006-01-27 2013-08-08 弱塩基性選択性セロトニン５−ｈｔ３遮断剤および有機酸を含む薬物送達系

Publications (3)

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JP2009524697A JP2009524697A (ja) 2009-07-02
JP2009524697A5 JP2009524697A5 (OSRAM) 2010-03-25
JP5433236B2 true JP5433236B2 (ja) 2014-03-05

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JP2008552611A Expired - Fee Related JP5433236B2 (ja) 2006-01-27 2007-01-29 弱塩基性選択性セロトニン５−ｈｔ３遮断剤および有機酸を含む薬物送達系
JP2013165542A Expired - Fee Related JP5918179B2 (ja) 2006-01-27 2013-08-08 弱塩基性選択性セロトニン５−ｈｔ３遮断剤および有機酸を含む薬物送達系
JP2015188001A Withdrawn JP2016014048A (ja) 2006-01-27 2015-09-25 弱塩基性選択性セロトニン５−ｈｔ３遮断剤および有機酸を含む薬物送達系

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JP2013165542A Expired - Fee Related JP5918179B2 (ja) 2006-01-27 2013-08-08 弱塩基性選択性セロトニン５−ｈｔ３遮断剤および有機酸を含む薬物送達系
JP2015188001A Withdrawn JP2016014048A (ja) 2006-01-27 2015-09-25 弱塩基性選択性セロトニン５−ｈｔ３遮断剤および有機酸を含む薬物送達系

Country Status (14)

Country Link
US (1) US20070190145A1 (OSRAM)
EP (2) EP2363117B1 (OSRAM)
JP (3) JP5433236B2 (OSRAM)
KR (1) KR101413613B1 (OSRAM)
CN (2) CN101410094B (OSRAM)
AU (1) AU2007211091B8 (OSRAM)
BR (1) BRPI0707324A2 (OSRAM)
CA (1) CA2640460C (OSRAM)
ES (2) ES2531215T3 (OSRAM)
IL (1) IL193020A0 (OSRAM)
NZ (1) NZ570039A (OSRAM)
RU (1) RU2490012C2 (OSRAM)
WO (1) WO2007090082A2 (OSRAM)
ZA (1) ZA200806497B (OSRAM)

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JP2016014048A (ja) 2016-01-28
CA2640460C (en) 2015-05-26
EP2363117B1 (en) 2015-08-19
EP1976491A2 (en) 2008-10-08
CN103211779A (zh) 2013-07-24
AU2007211091B8 (en) 2013-08-29
JP5918179B2 (ja) 2016-05-18
CN101410094B (zh) 2013-04-17
BRPI0707324A2 (pt) 2011-05-03
JP2009524697A (ja) 2009-07-02
WO2007090082A2 (en) 2007-08-09
ZA200806497B (en) 2009-12-30
JP2013249305A (ja) 2013-12-12
RU2008134912A (ru) 2010-03-10
RU2490012C2 (ru) 2013-08-20
EP2363117A1 (en) 2011-09-07
KR20080098627A (ko) 2008-11-11
CA2640460A1 (en) 2007-08-09
AU2007211091A8 (en) 2013-08-29
ES2531215T3 (es) 2015-03-11
WO2007090082A3 (en) 2007-12-21
EP1976491B1 (en) 2014-12-17
NZ570039A (en) 2011-07-29
ES2550035T3 (es) 2015-11-04
AU2007211091A1 (en) 2007-08-09
KR101413613B1 (ko) 2014-07-10
IL193020A0 (en) 2009-09-22
CN103211779B (zh) 2016-03-16
US20070190145A1 (en) 2007-08-16
AU2007211091B2 (en) 2013-05-02
CN101410094A (zh) 2009-04-15

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