JP5389325B2 - 前糖尿病患者および２型糖尿病患者における心血管系の罹病率および死亡率を低下させるための長時間作用型インスリン - Google Patents
前糖尿病患者および２型糖尿病患者における心血管系の罹病率および死亡率を低下させるための長時間作用型インスリン Download PDFInfo
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- JP5389325B2 JP5389325B2 JP2006500944A JP2006500944A JP5389325B2 JP 5389325 B2 JP5389325 B2 JP 5389325B2 JP 2006500944 A JP2006500944 A JP 2006500944A JP 2006500944 A JP2006500944 A JP 2006500944A JP 5389325 B2 JP5389325 B2 JP 5389325B2
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
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- Immunology (AREA)
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- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
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| US43994103P | 2003-01-14 | 2003-01-14 | |
| US60/439,941 | 2003-01-14 | ||
| PCT/US2004/000879 WO2004064862A1 (en) | 2003-01-14 | 2004-01-14 | Long acting insulin for reducing cardiovascular morbidity and mortality in prediabetic patients and patients with type 2 diabetes |
Publications (3)
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| JP2006515625A JP2006515625A (ja) | 2006-06-01 |
| JP2006515625A5 JP2006515625A5 (https=) | 2007-03-01 |
| JP5389325B2 true JP5389325B2 (ja) | 2014-01-15 |
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| JP2006500944A Expired - Lifetime JP5389325B2 (ja) | 2003-01-14 | 2004-01-14 | 前糖尿病患者および２型糖尿病患者における心血管系の罹病率および死亡率を低下させるための長時間作用型インスリン |
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| JP (1) | JP5389325B2 (https=) |
| AU (2) | AU2004206829B2 (https=) |
| BR (1) | BRPI0406499A (https=) |
| CA (1) | CA2512820C (https=) |
| CY (1) | CY1118738T1 (https=) |
| DK (1) | DK2596800T3 (https=) |
| ES (1) | ES2604359T3 (https=) |
| GB (1) | GB0309154D0 (https=) |
| HU (1) | HUE031892T2 (https=) |
| IL (3) | IL169697A (https=) |
| MX (1) | MXPA05007470A (https=) |
| PT (1) | PT2596800T (https=) |
| SI (1) | SI2596800T1 (https=) |
| WO (1) | WO2004064862A1 (https=) |
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| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| US6923175B2 (en) | 2002-03-20 | 2005-08-02 | Mannkind Corporation | Inhalation apparatus |
| DE602004021603D1 (de) * | 2003-07-25 | 2009-07-30 | Conjuchem Biotechnologies Inc | Insulinderivative mit langanhaltender wirkung und verfahren zu deren herstellung |
| ATE486064T1 (de) | 2004-08-20 | 2010-11-15 | Mannkind Corp | Katalyse der diketopiperazinsynthese |
| KR20130066695A (ko) | 2004-08-23 | 2013-06-20 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염 |
| MX373000B (es) | 2005-09-14 | 2020-05-21 | Mannkind Corp | Metodo para formulacion de farmaco basado en el aumento de la afinidad de agentes activos hacia las superficies de microparticulas cristalinas. |
| EP1986679B1 (en) | 2006-02-22 | 2017-10-25 | MannKind Corporation | A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent |
| CN101827626B (zh) | 2008-06-13 | 2015-03-18 | 曼金德公司 | 干粉吸入器和用于药物输送的系统 |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| ES2421385T3 (es) | 2008-06-20 | 2013-09-02 | Mannkind Corp | Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación |
| TWI532497B (zh) | 2008-08-11 | 2016-05-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| CN102256618A (zh) | 2008-10-17 | 2011-11-23 | 赛诺菲-安万特德国有限公司 | 胰岛素和glp-1激动剂的组合 |
| US10437962B2 (en) | 2008-12-23 | 2019-10-08 | Roche Diabetes Care Inc | Status reporting of a structured collection procedure |
| US9918635B2 (en) | 2008-12-23 | 2018-03-20 | Roche Diabetes Care, Inc. | Systems and methods for optimizing insulin dosage |
| US10456036B2 (en) * | 2008-12-23 | 2019-10-29 | Roche Diabetes Care, Inc. | Structured tailoring |
| US8849458B2 (en) * | 2008-12-23 | 2014-09-30 | Roche Diagnostics Operations, Inc. | Collection device with selective display of test results, method and computer program product thereof |
| CN102265280A (zh) * | 2008-12-23 | 2011-11-30 | 霍夫曼-拉罗奇有限公司 | 用于在收集设备上运行的结构化收集过程的实现、执行、数据收集和数据分析的管理方法和系统 |
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| KR102584844B1 (ko) | 2009-06-12 | 2023-10-04 | 맨카인드 코포레이션 | 한정된 비표면적을 갖는 디케토피페라진 마이크로입자 |
| PL2451437T3 (pl) | 2009-07-06 | 2017-05-31 | Sanofi-Aventis Deutschland Gmbh | Wodne preparaty insuliny zawierające metioninę |
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| TR201809460T4 (tr) | 2009-11-13 | 2018-07-23 | Sanofi Aventis Deutschland | Bir GLP- 1-agonisti, bir insülin ve metiyonin içeren farmasötik bileşim. |
| NZ599847A (en) | 2009-11-13 | 2013-09-27 | Sanofi Aventis Deutschland | Pharmaceutical composition comprising a glp-1 agonist and methionine |
| AU2011202239C1 (en) | 2010-05-19 | 2017-03-16 | Sanofi | Long-acting formulations of insulins |
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| CN102985125A (zh) | 2010-06-21 | 2013-03-20 | 曼金德公司 | 干粉药物输送系统和方法 |
| WO2012028172A1 (en) | 2010-08-30 | 2012-03-08 | Sanofi-Aventis Deutschland Gmbh | Use of ave0010 for the manufacture of a medicament for the treatment of diabetes mellitus type 2 |
| US20120173151A1 (en) | 2010-12-29 | 2012-07-05 | Roche Diagnostics Operations, Inc. | Methods of assessing diabetes treatment protocols based on protocol complexity levels and patient proficiency levels |
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| US9821032B2 (en) | 2011-05-13 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin |
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| TWI559929B (en) | 2011-09-01 | 2016-12-01 | Sanofi Aventis Deutschland | Pharmaceutical composition for use in the treatment of a neurodegenerative disease |
| MX2014004983A (es) | 2011-10-24 | 2014-09-22 | Mannkid Corp | Metodos y composiciones para tratar dolor. |
| EP2785366A1 (en) * | 2011-12-01 | 2014-10-08 | Sanofi | Insulin glargine versus metformin for the first-line treatment of early type 2 diabetes |
| WO2013144273A1 (en) * | 2012-03-28 | 2013-10-03 | Sanofi | Basal insulin therapy |
| KR102264177B1 (ko) | 2012-07-12 | 2021-06-11 | 맨카인드 코포레이션 | 건조 분말 약물 전달 시스템 및 방법 |
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| EP2983697B1 (en) | 2013-04-03 | 2018-10-31 | Sanofi | Treatment of diabetes mellitus by long acting formulations of insulins |
| MX375448B (es) | 2013-07-18 | 2025-03-06 | Mannkind Corp | Composiciones farmacéuticas en polvo seco estables al calor y métodos. |
| EP3030294B1 (en) | 2013-08-05 | 2020-10-07 | MannKind Corporation | Insufflation apparatus |
| US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
| WO2016001185A1 (en) * | 2014-07-02 | 2016-01-07 | Novo Nordisk A/S | Dosage regimen for the treatment of diabetes |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
| PE20171622A1 (es) | 2014-12-12 | 2017-11-02 | Sanofi Aventis Deutschland | Formulacion de relacion fija de insulina glargina/lixisenatida |
| TWI748945B (zh) | 2015-03-13 | 2021-12-11 | 德商賽諾菲阿凡提斯德意志有限公司 | 第２型糖尿病病患治療 |
| TW201705975A (zh) | 2015-03-18 | 2017-02-16 | 賽諾菲阿凡提斯德意志有限公司 | 第２型糖尿病病患之治療 |
| WO2017108943A1 (en) * | 2015-12-23 | 2017-06-29 | Sanofi-Aventis Deutschland Gmbh | Cardiac metabolic effect of lantus |
| WO2018096164A1 (en) * | 2016-11-28 | 2018-05-31 | Novo Nordisk A/S | Insulin degludec for treating diabetes |
| MA46890A (fr) * | 2016-11-28 | 2021-04-28 | Novo Nordisk As | Insuline degludec pour l'amélioration du contrôle glycémique et la réduction des complications du diabète aigu et à long terme |
| WO2018096162A1 (en) * | 2016-11-28 | 2018-05-31 | Novo Nordisk A/S | Insulin degludec in cardiovascular conditions |
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| CN119833121B (zh) * | 2025-01-09 | 2025-10-24 | 南通大学 | 一种糖尿病症状自动检测系统 |
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| US5354331A (en) | 1992-07-15 | 1994-10-11 | Schachar Ronald A | Treatment of presbyopia and other eye disorders |
| DE69826286T2 (de) * | 1997-06-27 | 2005-11-24 | Fujisawa Pharmaceutical Co., Ltd. | Derivate mit einem aromatischen ring |
| CO5271699A1 (es) * | 2000-01-24 | 2003-04-30 | Pfizer Prod Inc | Procedimiento para el tratamiento de cardiomiopatia utilizando inhibidores de la glucogeno fosforilasa |
| NZ522036A (en) * | 2000-04-19 | 2004-04-30 | Borody Thomas J | Compositions and therapies for hyperlipidaemia-associated disorders |
| MXPA03003733A (es) * | 2000-10-26 | 2004-10-15 | Fournier Lab Ireland Ltd | Combinacion de fenofibrato y coenzima q10 para el tratamiento de la disfuncion endotelial. |
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- 2004-01-14 EP EP13155801.7A patent/EP2596800B1/en not_active Expired - Lifetime
- 2004-01-14 HU HUE13155801A patent/HUE031892T2/en unknown
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- 2004-01-14 DK DK13155801.7T patent/DK2596800T3/en active
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- 2004-01-14 AU AU2004206829A patent/AU2004206829B2/en not_active Expired
- 2004-01-14 PT PT131558017T patent/PT2596800T/pt unknown
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- 2004-01-14 JP JP2006500944A patent/JP5389325B2/ja not_active Expired - Lifetime
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Also Published As
| Publication number | Publication date |
|---|---|
| PT2596800T (pt) | 2016-12-02 |
| US20080287343A1 (en) | 2008-11-20 |
| IL169697A (en) | 2011-06-30 |
| DK2596800T3 (en) | 2016-12-12 |
| IL197739A (en) | 2017-02-28 |
| US20110281793A1 (en) | 2011-11-17 |
| AU2010202738A1 (en) | 2010-07-22 |
| US8809270B2 (en) | 2014-08-19 |
| CY1118738T1 (el) | 2017-07-12 |
| US20130012433A1 (en) | 2013-01-10 |
| BRPI0406499A (pt) | 2005-12-06 |
| AU2004206829A1 (en) | 2004-08-05 |
| IL197739A0 (en) | 2011-08-01 |
| MXPA05007470A (es) | 2005-09-21 |
| IL208525A0 (en) | 2010-12-30 |
| WO2004064862A1 (en) | 2004-08-05 |
| EP2596800A1 (en) | 2013-05-29 |
| US7977310B2 (en) | 2011-07-12 |
| US20040229774A1 (en) | 2004-11-18 |
| IL169697A0 (en) | 2007-07-04 |
| GB0309154D0 (en) | 2003-05-28 |
| CA2512820A1 (en) | 2004-08-05 |
| EP2596800B1 (en) | 2016-08-24 |
| SI2596800T1 (sl) | 2017-04-26 |
| AU2004206829B2 (en) | 2010-04-08 |
| EP1589991A1 (en) | 2005-11-02 |
| ES2604359T3 (es) | 2017-03-06 |
| CA2512820C (en) | 2013-06-04 |
| US7405196B2 (en) | 2008-07-29 |
| AU2010202738B2 (en) | 2013-12-05 |
| JP2006515625A (ja) | 2006-06-01 |
| HUE031892T2 (en) | 2017-08-28 |
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