JP5372774B2 - クエン酸を含む多糖誘導体 - Google Patents
クエン酸を含む多糖誘導体 Download PDFInfo
- Publication number
- JP5372774B2 JP5372774B2 JP2009543535A JP2009543535A JP5372774B2 JP 5372774 B2 JP5372774 B2 JP 5372774B2 JP 2009543535 A JP2009543535 A JP 2009543535A JP 2009543535 A JP2009543535 A JP 2009543535A JP 5372774 B2 JP5372774 B2 JP 5372774B2
- Authority
- JP
- Japan
- Prior art keywords
- citric acid
- acid
- derivative according
- residue
- molecular weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B31/00—Preparation of derivatives of starch
- C08B31/02—Esters
- C08B31/04—Esters of organic acids, e.g. alkenyl-succinated starch
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/736—Chitin; Chitosan; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B3/00—Preparation of cellulose esters of organic acids
- C08B3/12—Preparation of cellulose esters of organic acids of polybasic organic acids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B33/00—Preparation of derivatives of amylose
- C08B33/02—Esters
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0018—Pullulan, i.e. (alpha-1,4)(alpha-1,6)-D-glucan; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
- C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
- C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0036—Galactans; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0084—Guluromannuronans, e.g. alginic acid, i.e. D-mannuronic acid and D-guluronic acid units linked with alternating alpha- and beta-1,4-glycosidic bonds; Derivatives thereof, e.g. alginates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06425873.4 | 2006-12-29 | ||
| EP06425873A EP1939219A1 (en) | 2006-12-29 | 2006-12-29 | Polysaccharides derivatised with citric acid |
| PCT/IB2007/003980 WO2008081257A2 (en) | 2006-12-29 | 2007-12-18 | Polysaccharides derivatised with citric acid |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010514879A JP2010514879A (ja) | 2010-05-06 |
| JP2010514879A5 JP2010514879A5 (enExample) | 2011-01-20 |
| JP5372774B2 true JP5372774B2 (ja) | 2013-12-18 |
Family
ID=37964263
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009543535A Expired - Fee Related JP5372774B2 (ja) | 2006-12-29 | 2007-12-18 | クエン酸を含む多糖誘導体 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8629252B2 (enExample) |
| EP (2) | EP1939219A1 (enExample) |
| JP (1) | JP5372774B2 (enExample) |
| AT (1) | ATE481425T1 (enExample) |
| AU (1) | AU2007341080A1 (enExample) |
| CA (1) | CA2673953A1 (enExample) |
| DE (1) | DE602007009306D1 (enExample) |
| DK (1) | DK2094734T3 (enExample) |
| ES (1) | ES2348215T3 (enExample) |
| PL (1) | PL2094734T3 (enExample) |
| PT (1) | PT2094734E (enExample) |
| SI (1) | SI2094734T1 (enExample) |
| WO (1) | WO2008081257A2 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102083862A (zh) * | 2008-04-01 | 2011-06-01 | 康奈尔大学 | 有机-可溶性壳聚糖盐和由其制备的壳聚糖衍生生物材料 |
| DE102010012183A1 (de) * | 2010-03-19 | 2011-09-22 | Fresenius Medical Care Deutschland Gmbh | Veresterte Polysaccharid-Osmotika |
| CN102492057B (zh) * | 2011-12-15 | 2013-07-10 | 石狮市华宝海洋生物化工有限公司 | 一种超高密度壳聚糖的制备方法 |
| US8697843B1 (en) | 2013-02-08 | 2014-04-15 | The United States Of America, As Represented By The Secretary Of Agriculture | Superabsorbant materials from chemically modified gluten |
| WO2015144438A1 (en) | 2014-03-25 | 2015-10-01 | Basf Se | Carboxylate ester of polysaccharide |
| US10982013B2 (en) * | 2014-06-02 | 2021-04-20 | Anavo Technologies, Llc | Modified biopolymers and methods of producing and using the same |
| CN108779387B (zh) | 2015-11-23 | 2022-07-01 | 艾纳沃技术有限责任公司 | 涂层颗粒以及该涂层颗粒的制备方法和使用方法 |
| PL3538066T3 (pl) | 2016-11-11 | 2022-05-02 | Anteis Sa | Wypełniacze skórne z kwasem hialuronowym usieciowane kwasem cytrynowym, sposób ich wytwarzania i ich zastosowania |
| WO2019110106A1 (de) | 2017-12-07 | 2019-06-13 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren zur vernetzung von polymeren mit nucleophilen funktionalitäten, vernetzte polymere sowie verwendungen hiervon |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2486803A (en) * | 1946-06-14 | 1949-11-01 | Henry H Frede & Company Inc | Absorbent fibrous sheets and method of making same |
| US2664397A (en) * | 1947-09-16 | 1953-12-29 | Phillips Petroleum Co | Ion-exchange resins from carboxyalkyl cellulose ethers |
| US2759787A (en) * | 1953-05-15 | 1956-08-21 | Eastman Kodak Co | Cellulose citrates and their preparation |
| US3097051A (en) * | 1958-11-18 | 1963-07-09 | Ricardo H Wade | Cellulose ester anhydrides in fiber form |
| GB1229527A (enExample) * | 1968-12-12 | 1971-04-21 | Warner Lambert Pharmaceutical | |
| DK354479A (da) * | 1978-10-11 | 1980-04-12 | Pfizer | Carboxylerede celluose-ion-byttematerialer fremgangsmaade til deres fremstilling samt deres anvendelse til fjernelse af tungmetalioner fra vandige oploesninger |
| IT1213330B (it) * | 1986-08-28 | 1989-12-20 | Rol Spa | Tensioattivi derivati da idrossiacidi bi- o tri-carbossilici. |
| IT1219587B (it) * | 1988-05-13 | 1990-05-18 | Fidia Farmaceutici | Polisaccaridi carbossiilici autoreticolati |
| JP4414670B2 (ja) * | 2003-04-10 | 2010-02-10 | 松谷化学工業株式会社 | イオン交換能力を有するグルコースポリマーの製造法及びそれを含有する組成物 |
| DE102004054842A1 (de) * | 2004-11-12 | 2006-05-24 | Cognis Ip Management Gmbh | Ölhaltige Tensidgele |
-
2006
- 2006-12-29 EP EP06425873A patent/EP1939219A1/en not_active Withdrawn
-
2007
- 2007-12-18 JP JP2009543535A patent/JP5372774B2/ja not_active Expired - Fee Related
- 2007-12-18 AU AU2007341080A patent/AU2007341080A1/en not_active Abandoned
- 2007-12-18 US US12/521,308 patent/US8629252B2/en active Active
- 2007-12-18 CA CA002673953A patent/CA2673953A1/en not_active Abandoned
- 2007-12-18 PT PT07859099T patent/PT2094734E/pt unknown
- 2007-12-18 DK DK07859099.9T patent/DK2094734T3/da active
- 2007-12-18 SI SI200730403T patent/SI2094734T1/sl unknown
- 2007-12-18 ES ES07859099T patent/ES2348215T3/es active Active
- 2007-12-18 WO PCT/IB2007/003980 patent/WO2008081257A2/en not_active Ceased
- 2007-12-18 DE DE602007009306T patent/DE602007009306D1/de active Active
- 2007-12-18 PL PL07859099T patent/PL2094734T3/pl unknown
- 2007-12-18 EP EP07859099A patent/EP2094734B9/en active Active
- 2007-12-18 AT AT07859099T patent/ATE481425T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008081257A2 (en) | 2008-07-10 |
| DE602007009306D1 (de) | 2010-10-28 |
| SI2094734T1 (sl) | 2010-12-31 |
| ES2348215T3 (es) | 2010-12-01 |
| US20100311687A1 (en) | 2010-12-09 |
| CA2673953A1 (en) | 2008-07-10 |
| WO2008081257A3 (en) | 2008-08-28 |
| PL2094734T3 (pl) | 2011-03-31 |
| DK2094734T3 (da) | 2010-11-15 |
| EP2094734B9 (en) | 2010-12-22 |
| EP1939219A1 (en) | 2008-07-02 |
| ATE481425T1 (de) | 2010-10-15 |
| EP2094734B1 (en) | 2010-09-15 |
| AU2007341080A1 (en) | 2008-07-10 |
| PT2094734E (pt) | 2010-10-12 |
| US8629252B2 (en) | 2014-01-14 |
| EP2094734A2 (en) | 2009-09-02 |
| JP2010514879A (ja) | 2010-05-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5372774B2 (ja) | クエン酸を含む多糖誘導体 | |
| CA2710123C (en) | Polysaccharide derivatives of lipoic acid, and their preparation and use as skin cosmetics and medical devices | |
| JP5372773B2 (ja) | 酸性多糖類の誘導体 | |
| US20040167098A1 (en) | Cross-linked polysaccharides | |
| EP2173775B1 (en) | Hyaluronic acid derivatives containing groups able to release no | |
| US20100204177A1 (en) | Process for preparing thermosensitive (poly(ethylene oxide) poly(propylene oxide)) derivates that can be used to functionalize chitosan | |
| JP5527898B2 (ja) | 視認性医療用処置材 | |
| JP5236218B2 (ja) | 医療用処置材 | |
| Casadei et al. | Physical gels of a carboxymethyl derivative of scleroglucan: Synthesis and characterization | |
| JP7747335B2 (ja) | 架橋ヒアルロン酸ブチレートまたはブチレート-ホルメート誘導体およびその架橋方法 | |
| KR20250096719A (ko) | 타마린드 씨앗 다당류의 유도체 및 이의 제조 방법 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20101124 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20101124 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20130108 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20130405 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20130430 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20130820 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20130918 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 5372774 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| LAPS | Cancellation because of no payment of annual fees |